ID L7ESF7_9ACTN Unreviewed; 693 AA.
AC L7ESF7;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 24-JAN-2024, entry version 39.
DE RecName: Full=Protein-L-isoaspartate O-methyltransferase {ECO:0000256|ARBA:ARBA00013346};
DE EC=2.1.1.77 {ECO:0000256|ARBA:ARBA00011890};
DE AltName: Full=L-isoaspartyl protein carboxyl methyltransferase {ECO:0000256|ARBA:ARBA00031350};
DE AltName: Full=Protein L-isoaspartyl methyltransferase {ECO:0000256|ARBA:ARBA00030757};
DE AltName: Full=Protein-beta-aspartate methyltransferase {ECO:0000256|ARBA:ARBA00031323};
GN ORFNames=STRTUCAR8_04708 {ECO:0000313|EMBL:ELP61611.1};
OS Streptomyces turgidiscabies Car8.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=698760 {ECO:0000313|EMBL:ELP61611.1, ECO:0000313|Proteomes:UP000010931};
RN [1] {ECO:0000313|EMBL:ELP61611.1, ECO:0000313|Proteomes:UP000010931}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Car8 {ECO:0000313|EMBL:ELP61611.1,
RC ECO:0000313|Proteomes:UP000010931};
RX PubMed=21087627; DOI=10.1016/j.plasmid.2010.11.002;
RA Huguet-Tapia J.C., Badger J.H., Loria R., Pettis G.S.;
RT "Streptomyces turgidiscabies Car8 contains a modular pathogenicity island
RT that shares virulence genes with other actinobacterial plant pathogens.";
RL Plasmid 65:118-124(2011).
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily. L-
CC isoaspartyl/D-aspartyl protein methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00005369}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELP61611.1}.
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DR EMBL; AEJB01000670; ELP61611.1; -; Genomic_DNA.
DR RefSeq; WP_006383498.1; NZ_AEJB01000670.1.
DR AlphaFoldDB; L7ESF7; -.
DR STRING; 85558.T45_06658; -.
DR PATRIC; fig|698760.3.peg.9430; -.
DR Proteomes; UP000010931; Unassembled WGS sequence.
DR GO; GO:0004719; F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity; IEA:InterPro.
DR GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR027573; Methyltran_FxLD.
DR InterPro; IPR000682; PCMT.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR023809; Thiopep_bacteriocin_synth_dom.
DR NCBIfam; TIGR04364; methyltran_FxLD; 1.
DR NCBIfam; TIGR03891; thiopep_ocin; 1.
DR PANTHER; PTHR11579; PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE; 1.
DR PANTHER; PTHR11579:SF0; PROTEIN-L-ISOASPARTATE(D-ASPARTATE) O-METHYLTRANSFERASE; 1.
DR Pfam; PF14028; Lant_dehydr_C; 1.
DR Pfam; PF01135; PCMT; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000010931}.
FT DOMAIN 6..254
FT /note="Thiopeptide-type bacteriocin biosynthesis"
FT /evidence="ECO:0000259|Pfam:PF14028"
SQ SEQUENCE 693 AA; 74636 MW; 24AF6B8B42857A4F CRC64;
MRSDRWQQHN ITFVDRERAR RVIAERIGPA LITAEADGQL TGWWFMNKQP WPLRYLAAEP
SPVIESLLSD LVGDGAAVSW LPCIYEPETD TFGGPEAMDA AHELFHSDSH HLLTYQPSPE
HLGHRETAVL LASAMMRGAG LDWFEQGDVW AKVAALRPAI TPLLPERVAE LVPAIRKLMA
ADAHGLCRPD GPLHAHDEWV TAFERAGATL ACLAGRGALT RGLRAVITHH VIFHANRAGL
LRDDQSALSN IAREVIMGTS DNTASPDAAP AAADSVSAVN TDTIATPTAD AERLRNALVD
QLRAEGHART TAVETALRTV PRHVFVPDAS LEDAYANAPV HIKYDTDGTS ISCASQPGVV
ALMLDQLDAQ PGQRVLELGA GTGYNAGLLA SLVGESGHVT TLDVDDDLVE GASAHLAAAG
ITNVEAVTRD GALGYAEGAP YDRIIATVGA HGVPHSWLQQ LAPGGRLLVP QRLKGSVSRS
IAYEQRDGQW VSLGSEMNTF MPLRRGIADD DRRVVPLSAD GTVRLQAPAG QNIDADALAG
VLDQPRTEEW TGMTVRAMES PEWMELFVTC SVPSGLIRML FPQGAKDGLL TEDPYPSSTA
AVDKGAVTYL ARRLSQEKTL EGGKLWEFGV IGHGPGSDEL VVKVADAIRT WDRDYRDHEA
AFEIQSLDAP AIGHRPGLFA LDTPLNRIVV DWQ
//
