ID   L7FEF7_9ACTN            Unreviewed;       371 AA.
AC   L7FEF7;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   24-JAN-2024, entry version 40.
DE   RecName: Full=alcohol dehydrogenase {ECO:0000256|ARBA:ARBA00013190};
DE            EC=1.1.1.1 {ECO:0000256|ARBA:ARBA00013190};
GN   ORFNames=STRTUCAR8_00897 {ECO:0000313|EMBL:ELP69773.1};
OS   Streptomyces turgidiscabies Car8.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=698760 {ECO:0000313|EMBL:ELP69773.1, ECO:0000313|Proteomes:UP000010931};
RN   [1] {ECO:0000313|EMBL:ELP69773.1, ECO:0000313|Proteomes:UP000010931}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Car8 {ECO:0000313|EMBL:ELP69773.1,
RC   ECO:0000313|Proteomes:UP000010931};
RX   PubMed=21087627; DOI=10.1016/j.plasmid.2010.11.002;
RA   Huguet-Tapia J.C., Badger J.H., Loria R., Pettis G.S.;
RT   "Streptomyces turgidiscabies Car8 contains a modular pathogenicity island
RT   that shares virulence genes with other actinobacterial plant pathogens.";
RL   Plasmid 65:118-124(2011).
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC       family. {ECO:0000256|ARBA:ARBA00008072}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ELP69773.1}.
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DR   EMBL; AEJB01000123; ELP69773.1; -; Genomic_DNA.
DR   RefSeq; WP_006374916.1; NZ_AEJB01000123.1.
DR   AlphaFoldDB; L7FEF7; -.
DR   STRING; 85558.T45_06861; -.
DR   PATRIC; fig|698760.3.peg.1561; -.
DR   Proteomes; UP000010931; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   PANTHER; PTHR42940; ALCOHOL DEHYDROGENASE 1-RELATED; 1.
DR   PANTHER; PTHR42940:SF8; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 11; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000010931}.
FT   DOMAIN          31..362
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
SQ   SEQUENCE   371 AA;  38882 MW;  80BA2AE9CFEC96C2 CRC64;
     MSDTLTLSEL GWSRALPVTA TMRAMLFRRF GPPEVLEQAT VETPHPGPGE VLVQVAAVGI
     GRLLDLTARA GNHPYVRIDP PHILGADHAG TVAALGAGVD SVRVGDRVAV IPPVACGRCS
     YCAEGREEVC DELTLIGNHR PGAYAQYCAV PARNVHRVPD GIPAAMAASL ALLGAVAANQ
     MTQAGLRPGH WVLVQGASSA LGSTTAAYAR HLGAKVISTS RSADKRAAMA AAGADLVLDT
     NAPDFVKRVR EATGGRGVDI AVDNLGDPDV WDATIDSLAR GGAVVTSGAF LGGKVGIDLR
     RVYSDCHRII GVRTGNPAAV AELWTQVENG FRAVVDRTFP ISRAADAHRY MEDDNSLGRV
     ALTVRPEDWD A
//