ID   L7LKX8_9ACTN            Unreviewed;       595 AA.
AC   L7LKX8;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   RecName: Full=FAD-dependent oxidoreductase 2 FAD binding domain-containing protein {ECO:0000259|Pfam:PF00890};
GN   ORFNames=GSI01S_11_00390 {ECO:0000313|EMBL:GAC60698.1};
OS   Gordonia sihwensis NBRC 108236.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Gordoniaceae;
OC   Gordonia.
OX   NCBI_TaxID=1223544 {ECO:0000313|EMBL:GAC60698.1, ECO:0000313|Proteomes:UP000035083};
RN   [1] {ECO:0000313|EMBL:GAC60698.1, ECO:0000313|Proteomes:UP000035083}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 108236 {ECO:0000313|EMBL:GAC60698.1,
RC   ECO:0000313|Proteomes:UP000035083};
RA   Yoshida I., Hosoyama A., Tsuchikane K., Ando Y., Baba S., Ohji S.,
RA   Hamada M., Tamura T., Yamazoe A., Yamazaki S., Fujita N.;
RT   "Whole genome shotgun sequence of Gordonia sihwensis NBRC 108236.";
RL   Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAC60698.1}.
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DR   EMBL; BANU01000011; GAC60698.1; -; Genomic_DNA.
DR   AlphaFoldDB; L7LKX8; -.
DR   eggNOG; COG3573; Bacteria.
DR   Proteomes; UP000035083; Unassembled WGS sequence.
DR   GO; GO:0033765; F:steroid dehydrogenase activity, acting on the CH-CH group of donors; IEA:UniProt.
DR   GO; GO:0008152; P:metabolic process; IEA:UniProt.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   Gene3D; 3.90.700.10; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR   InterPro; IPR003953; FAD-binding_2.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR014614; KsdD_DH.
DR   InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR   InterPro; IPR006311; TAT_signal.
DR   PANTHER; PTHR43260; 3-KETOSTEROID-DELTA-1-DEHYDROGENASE; 1.
DR   PANTHER; PTHR43260:SF1; KSDD-LIKE STEROID DEHYDROGENASE RV0785; 1.
DR   Pfam; PF00890; FAD_binding_2; 1.
DR   PIRSF; PIRSF036654; UCP036654; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   PROSITE; PS51318; TAT; 1.
PE   4: Predicted;
KW   Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000035083}.
FT   DOMAIN          44..577
FT                   /note="FAD-dependent oxidoreductase 2 FAD binding"
FT                   /evidence="ECO:0000259|Pfam:PF00890"
SQ   SEQUENCE   595 AA;  64130 MW;  26E4C27608CD3769 CRC64;
     MPAEFNPTIT RRQALAAGGA AVAAALVAPG HGIAAAAGPS PDADVIIVGH GLSGLVAASE
     LADRGRKVLI VDQESGQNVG AQAHWSLGGL FFIDSPEQRL AGIRDSHERA HRDWFATAGF
     DRSPHSVDGE DYWARRWAEK YLEFAAGEKR SWLAGMGVSW VPVVGWAERG NGVPGTPGNT
     VPRFHTTLGT GPGVVEPFVR RVREAQRRGR IRFAFRHRVD ELITAQGAVV GVRGCVLEPS
     SLPRGKASSR KQIGDFELHA PLVIVASGGI GGNHDLVRRN WPARLGTAPE FMVTGVPQHV
     DGRMLGIAER SGARLVNRDR MWHYTEGLRN HSPIWPGHGI RVLGAPSSMW FDAAGRRFGE
     PGIPSHDTLG TLELIQRSGY DYSWFVLNKR IIEKEFVLSG SEQNPELTAK NLPLYLVHRA
     TDDVPKPVQA FLDRGPDFVT AGSVEALTAK MNALVGTDLV DPGSLKKQIA HRDREAFNPK
     STDPQIKSIR RSLAYVGDNL VRTVPMHRIL DRDAGPLIAI KMNILTRKSL GGLQTDLSGR
     VLSADGRPVE GLMAVGEASG FGGGGVHGYR ALEGTFLGGC LFTGRTAGRA AHRLL
//