ID L7UF88_MYXSD Unreviewed; 538 AA.
AC L7UF88;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN OrderedLocusNames=MYSTI_05244 {ECO:0000313|EMBL:AGC46525.1};
OS Myxococcus stipitatus (strain DSM 14675 / JCM 12634 / Mx s8).
OC Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
OC Myxococcaceae; Myxococcus.
OX NCBI_TaxID=1278073 {ECO:0000313|EMBL:AGC46525.1, ECO:0000313|Proteomes:UP000011131};
RN [1] {ECO:0000313|EMBL:AGC46525.1, ECO:0000313|Proteomes:UP000011131}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14675 / JCM 12634 / Mx s8
RC {ECO:0000313|Proteomes:UP000011131};
RX PubMed=23516218; DOI=10.1128/genomeA.00100-13;
RA Huntley S., Kneip S., Treuner-Lange A., Sogaard-Andersen L.;
RT "Complete genome sequence of Myxococcus stipitatus strain DSM 14675, a
RT fruiting myxobacterium.";
RL Genome Announc. 1:E0010013-E0010013(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP004025; AGC46525.1; -; Genomic_DNA.
DR AlphaFoldDB; L7UF88; -.
DR STRING; 1278073.MYSTI_05244; -.
DR KEGG; msd:MYSTI_05244; -.
DR PATRIC; fig|1278073.3.peg.5314; -.
DR eggNOG; COG4191; Bacteria.
DR HOGENOM; CLU_495926_0_0_7; -.
DR Proteomes; UP000011131; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR43065:SF10; PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK3; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:AGC46525.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000313|EMBL:AGC46525.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..42
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 279..297
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 326..536
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 538 AA; 57888 MW; 40E9A3F5144BC426 CRC64;
MPTLTPTPGQ LAHAQRRGGR SALLGLGLVG VVALTSPVLG YLEDVGNARE ELLGHLSNQA
RVQADALGVH LLLLEAELAR VAEHPTLFPE DGASPAERAL LDSAFYHSSL FSEGVALLGP
RGERVWSDPP GMSLGVVPIT SRPWFQRMLE RKTPTIDLLE GEGGPLVVAV PLVKEGQIKG
VLLGEVRTEA LPTRSTEETA LFLMDARGRL LLPATSRSYQ EGFAESLRPL ARAPGPLMMD
GTRMMGAAAW VGRSELLLVV LEEEETATAG LRSRFLRQLA FHIALLTCTL GLFLVLLRHS
YRSLLEAEER LRRQETMAAL GTAAALIAHE VKNALNGIQA ALSVLRKTPA GSELPVRGLR
SQVERLGHLA RSLLSFGAPR AALRRNCEMR LLVEDALQAV RMLPESEEVE LRTSLEENLT
VQGDAALLVS AIDNLVRNAV EAGAVAKDTG LRPSPWVVVN LTREGADAVL VVEDNAGGVD
PRLEPRLWEP FATGRAKGVG LGLPMARTSV EAHGGSLTYT RRPLGSLFTL RLPLESTS
//
