ID L8FMD9_PSED2 Unreviewed; 873 AA.
AC L8FMD9;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=HTH APSES-type domain-containing protein {ECO:0000259|PROSITE:PS51299};
GN ORFNames=GMDG_05250 {ECO:0000313|EMBL:ELR02090.1};
OS Pseudogymnoascus destructans (strain ATCC MYA-4855 / 20631-21) (Bat
OS white-nose syndrome fungus) (Geomyces destructans).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=658429 {ECO:0000313|EMBL:ELR02090.1, ECO:0000313|Proteomes:UP000011064};
RN [1] {ECO:0000313|Proteomes:UP000011064}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4855 / 20631-21 {ECO:0000313|Proteomes:UP000011064};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C.A., Blehert D.S., Lorch J.M., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C., Freedman E.,
RA Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D.,
RA Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A., Murphy C.,
RA Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The genome sequence of Geomyces destructans 20631-21.";
RL Submitted (SEP-2010) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GL573276; ELR02090.1; -; Genomic_DNA.
DR RefSeq; XP_012743678.1; XM_012888224.1.
DR AlphaFoldDB; L8FMD9; -.
DR STRING; 658429.L8FMD9; -.
DR VEuPathDB; FungiDB:GMDG_05250; -.
DR HOGENOM; CLU_009666_1_1_1; -.
DR InParanoid; L8FMD9; -.
DR OrthoDB; 3019647at2759; -.
DR Proteomes; UP000011064; Unassembled WGS sequence.
DR GO; GO:0090575; C:RNA polymerase II transcription regulator complex; IEA:UniProt.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:UniProt.
DR GO; GO:0048315; P:conidium formation; IEA:UniProtKB-KW.
DR GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 3.10.260.10; Transcription regulator HTH, APSES-type DNA-binding domain; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR036887; HTH_APSES_sf.
DR InterPro; IPR018004; KilA/APSES_HTH.
DR InterPro; IPR003163; Tscrpt_reg_HTH_APSES-type.
DR PANTHER; PTHR43828; ASPARAGINASE; 1.
DR PANTHER; PTHR43828:SF3; REGULATORY PROTEIN SWI6; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF13637; Ank_4; 1.
DR Pfam; PF04383; KilA-N; 1.
DR SMART; SM00248; ANK; 2.
DR SMART; SM01252; KilA-N; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF54616; DNA-binding domain of Mlu1-box binding protein MBP1; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 2.
DR PROSITE; PS50088; ANK_REPEAT; 2.
DR PROSITE; PS51299; HTH_APSES; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Coiled coil {ECO:0000256|SAM:Coils};
KW Conidiation {ECO:0000256|ARBA:ARBA00023321};
KW Reference proteome {ECO:0000313|Proteomes:UP000011064};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Sporulation {ECO:0000256|ARBA:ARBA00022969};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 106..213
FT /note="HTH APSES-type"
FT /evidence="ECO:0000259|PROSITE:PS51299"
FT REPEAT 448..480
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 589..621
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REGION 1..82
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 269..359
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 789..823
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 282..339
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 873 AA; 95802 MW; 66A323D7A60E19C3 CRC64;
MASTTIAAFP PTSSNPYPRP TSSSQHSHHR TLSFASNQSN HDTVTGQVLP ASSAPAPSPS
PFNQNSQMSF SMSQGSQGNG LMMQPDAYRQ FADQNAPSMT VPTPQIYSAV YSGVDVYEME
VNRIAVMRRR KDSWLNATQI LKVAGIEKGK RTKVLEKEIL IGEHEKVQGG YGKYQGTWIK
FEKGLEFCRQ YGVEEILRPL LTYDMGQDGG IAGHGGVDTP TKEQAMAANR KRLYNAGNEA
RLSGQSGTFF KNISSTASHA VAAISKARFD SPAPRIRNGN RPPGFSRQSS QQQLDENAFP
GSQQSMQSFA SESSYNMNGD SAYATQSGPH FSHMGSQNEF QEPPRKRVRP SPSVSLSHQT
DGFYDMREPS PTEPNDSFVY HQHAQNTLQD DVVPLPLPPL PFSSSQTAES KRALLMSLFM
DQTRNEFSRH EAFVSLSGED LDMPIDNTAH TALHWAATLA RLPLLRALIN SGASIYRVNN
AGETALMRAC AVTNNLDFSA FPDLLELLGP TIEMKDGRGR TVLHHIAVTS AVKGRSQASK
YYLESLLEFV VRQGSAPSSQ QMFLGQAPAV KSMGIGRFMS EIVNAQDKSG DTALNIAARV
GNRSIISQLL EVGADAGIPN RAGLRPVDFG IGDPTEVGER PSTTVDKSLN KANRENSGDV
ISSITTLLSQ TEAEFAQEMT AKQSAIDSIH TQLRSSSAHL GEERRRLERL QHLAKARDER
KCKITNLRRA GDEEFFRLQQ IRAQQAPLAG QSEDMYLGEA DVAFACLPQN VGPDEVLRNP
ALVATVPGHG TLRARVAAYR ANNERLERAV GELRSKSREL EAKYRKTISL CSRVPEERID
DVLEGLWRAV DSEGGDVELG RVREFLTRVE GVE
//
