ID L8FME0_PSED2 Unreviewed; 1168 AA.
AC L8FME0;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE RecName: Full=Bms1-type G domain-containing protein {ECO:0000259|PROSITE:PS51714};
GN ORFNames=GMDG_05255 {ECO:0000313|EMBL:ELR02095.1};
OS Pseudogymnoascus destructans (strain ATCC MYA-4855 / 20631-21) (Bat
OS white-nose syndrome fungus) (Geomyces destructans).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=658429 {ECO:0000313|EMBL:ELR02095.1, ECO:0000313|Proteomes:UP000011064};
RN [1] {ECO:0000313|Proteomes:UP000011064}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4855 / 20631-21 {ECO:0000313|Proteomes:UP000011064};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C.A., Blehert D.S., Lorch J.M., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C., Freedman E.,
RA Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D.,
RA Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A., Murphy C.,
RA Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The genome sequence of Geomyces destructans 20631-21.";
RL Submitted (SEP-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
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DR EMBL; GL573276; ELR02095.1; -; Genomic_DNA.
DR RefSeq; XP_012743683.1; XM_012888229.1.
DR AlphaFoldDB; L8FME0; -.
DR STRING; 658429.L8FME0; -.
DR VEuPathDB; FungiDB:GMDG_05255; -.
DR HOGENOM; CLU_002486_0_0_1; -.
DR InParanoid; L8FME0; -.
DR OrthoDB; 5478101at2759; -.
DR Proteomes; UP000011064; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR CDD; cd01882; BMS1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR012948; AARP2CN.
DR InterPro; IPR039761; Bms1/Tsr1.
DR InterPro; IPR037875; Bms1_N.
DR InterPro; IPR007034; BMS1_TSR1_C.
DR InterPro; IPR030387; G_Bms1/Tsr1_dom.
DR InterPro; IPR006073; GTP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR12858; RIBOSOME BIOGENESIS PROTEIN; 1.
DR PANTHER; PTHR12858:SF2; RIBOSOME BIOGENESIS PROTEIN BMS1 HOMOLOG; 1.
DR Pfam; PF08142; AARP2CN; 1.
DR Pfam; PF01926; MMR_HSR1; 1.
DR Pfam; PF04950; RIBIOP_C; 1.
DR SMART; SM00785; AARP2CN; 1.
DR SMART; SM01362; DUF663; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51714; G_BMS1; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000011064};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517}.
FT DOMAIN 63..228
FT /note="Bms1-type G"
FT /evidence="ECO:0000259|PROSITE:PS51714"
FT REGION 1..44
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 314..333
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 394..501
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 549..578
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 611..670
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1092..1130
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 315..333
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 402..423
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 424..447
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 448..471
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 620..659
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1168 AA; 133004 MW; D97DB5DBB56300D8 CRC64;
MEDQTNRPHR PQKEKKKHTG DRNPKAFAFA NPGRLAKTSA RSSDVKERRL HVPLVDRIPD
EPPPRLVAIV GPPGVGKTTL LKSLVKRYAK ETLSEPQGPI TVITSKRQRL TFVECPNELE
AMVDMSKVAD IVLLMIDGNF GFEMETMEFL NILSASGMPG NVFGILTHLD MFKKPQTLKD
AKKRLKNRFW SELYQGAHLF YLSGVINGRY PDREIHNLSR FLSVMKNPRP LIWRNAHPYT
VIDSFRDITH PMKIEEDEKC DRTVVLSGYL RGTNFAAQGQ RVHIPGLGDY TISSMESLPD
PCPTPYMDQA LAKATGRTGR RRLDEKEKRL HAPMSDKSGL KIEGDTIWIT REKGFNFDKD
DEDTERGQGE GLIVGLQGER RLLGQTDDGV RLFSNGETIQ DVEEEDTGRK QPRKARFVDT
EGDSDAEDGA EEDFDSGDEE LDPEGEAEIS EERLGKAFRK EKEDKAGGDI AFADSDSDMG
SLLTGGESDK DDEYDSEEEG AQWKKNMIAN AMKIHGQKRS YRTADLARLM YDESLTPTEV
LNRWRGEIEE ENIEDDSDDD DFIKKTSPGK DGGLAEDRMV PVFDYEQLEE KWSVADNIDA
LRRRFATADL LKDKKGGSSD DDSDEDEDEE DSDNEGDGEF EDLEADDEEE GDKEDDEPND
IEAEREKNAR RKEELKLRFE EEDREGFNND KAIARREGGG DEEFGEDDWY DAQKAVIQKQ
LNINKSEFES LDDRSRVNVE GFRAGQYAKI VIEGVPSEFV TRFEPRMPII AGGINATEDR
FGFVQVRIKR HRWHKKILKT NDPLIFSLGW RRFQTLPVYS ISDSRIRNRM LKYTPEHMHC
FGTFYGPLIA PNTGFSCFQS FSAKTPGFRI AATGTVLNVD ESTEIVKKLK LTGVPYKIFK
NTSFIKDMFS TSLEIAKFEG ASIKTVSGVR GQIKRALAKP EGHFRATFED KILMSDIVFL
RAWFPVRPHR FYNPVTNLLG WAPMRLTGQV RRDEALPTPQ QNNSQYKPVE RVARVFNPLR
VPRQLAAELP FKSQITRMKK GKEETYMQKR AVVVGGEEKK ARNLMQQLMT LRKEKVAKRR
VANEKKRVEY RKKVAENEEK RGRGRRGRSR SIGRGRGRSG GVGMRGEGEE GQVREIEGGV
LVNINSGLKW NRVWNIRVMV FPDDGIPR
//
