ID L8FVA3_PSED2 Unreviewed; 562 AA.
AC L8FVA3;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 13-SEP-2023, entry version 47.
DE RecName: Full=GTPase of the mitochondrial inner membrane that associates with the large ribosomal subunit {ECO:0008006|Google:ProtNLM};
GN ORFNames=GMDG_01484 {ECO:0000313|EMBL:ELR04408.1};
OS Pseudogymnoascus destructans (strain ATCC MYA-4855 / 20631-21) (Bat
OS white-nose syndrome fungus) (Geomyces destructans).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=658429 {ECO:0000313|EMBL:ELR04408.1, ECO:0000313|Proteomes:UP000011064};
RN [1] {ECO:0000313|Proteomes:UP000011064}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4855 / 20631-21 {ECO:0000313|Proteomes:UP000011064};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C.A., Blehert D.S., Lorch J.M., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C., Freedman E.,
RA Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D.,
RA Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A., Murphy C.,
RA Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The genome sequence of Geomyces destructans 20631-21.";
RL Submitted (SEP-2010) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GL573186; ELR04408.1; -; Genomic_DNA.
DR RefSeq; XP_012739881.1; XM_012884427.1.
DR AlphaFoldDB; L8FVA3; -.
DR STRING; 658429.L8FVA3; -.
DR VEuPathDB; FungiDB:GMDG_01484; -.
DR HOGENOM; CLU_011747_2_6_1; -.
DR InParanoid; L8FVA3; -.
DR OrthoDB; 232786at2759; -.
DR Proteomes; UP000011064; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-UniRule.
DR CDD; cd01898; Obg; 1.
DR Gene3D; 2.70.210.12; GTP1/OBG domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR031167; G_OBG.
DR InterPro; IPR006073; GTP-bd.
DR InterPro; IPR006169; GTP1_OBG_dom.
DR InterPro; IPR036726; GTP1_OBG_dom_sf.
DR InterPro; IPR045086; OBG_GTPase.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11702; DEVELOPMENTALLY REGULATED GTP-BINDING PROTEIN-RELATED; 1.
DR PANTHER; PTHR11702:SF31; MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 2; 1.
DR Pfam; PF01018; GTP1_OBG; 2.
DR Pfam; PF01926; MMR_HSR1; 1.
DR PRINTS; PR00326; GTP1OBG.
DR SUPFAM; SSF82051; Obg GTP-binding protein N-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51710; G_OBG; 1.
DR PROSITE; PS51883; OBG; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000011064}.
FT DOMAIN 85..313
FT /note="Obg"
FT /evidence="ECO:0000259|PROSITE:PS51883"
FT DOMAIN 314..561
FT /note="OBG-type G"
FT /evidence="ECO:0000259|PROSITE:PS51710"
FT REGION 455..482
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 467..482
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 562 AA; 60918 MW; 738760FA52D493F4 CRC64;
MPPRCPTASG TLTPFLYPFL CTTTTPRTLP RLAQKCFSRR HPPRHLSTTP RALSADLDPL
SSVPVHLNNQ PVSHLNPPPS DYGRTIFSDR ATVHLHAGDG GHGCISFLKE KYIAAGPANG
GDGGYGGSIY IQAVRGETSL HKLARRNIIK AGRGKNGQGK TRGGERGDDV VIQVPVGTVI
REIERVDPVS NEELKLQFQG DAPEGDVREH AGPYKWDRDK WLLYPAITPE DIATADFPTL
PRARRSHLAS AQEMAPINLD LSQPMEKPIL LAAGAVGGLG NPHFVSQGAS RPKYATKGSE
GLHITLELEL KLLADVGLVG LPNAGKSTLL RAVSNSRARV GNWAFTTLQP NIGTVVLDNH
KGRPLTVSSY ETGEPRTNYT IADIPGLVKD AHLDRGLGVS FLRHVERARV LAFVIDLAAG
DAVTALKSLW REVGMYERMK IEEEVAKEKK EQIVKWSPIQ QNQDKDEPRG SSYHDKVPRS
EDAGGIASKP WFVVASKADL EGSQENYAGL KAYLGRVTKG EEEHPSGQKD GYVKDLVALP
ISAINGHGVD GITKLVVGML NE
//
