ID L8HR19_9CETA Unreviewed; 189 AA.
AC L8HR19;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE RecName: Full=HTH CENPB-type domain-containing protein {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=M91_01358 {ECO:0000313|EMBL:ELR46283.1};
OS Bos mutus (wild yak).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=72004 {ECO:0000313|EMBL:ELR46283.1, ECO:0000313|Proteomes:UP000011080};
RN [1] {ECO:0000313|EMBL:ELR46283.1, ECO:0000313|Proteomes:UP000011080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=yakQH1 {ECO:0000313|Proteomes:UP000011080};
RX PubMed=22751099; DOI=10.1038/ng.2343;
RA Qiu Q., Zhang G., Ma T., Qian W., Wang J., Ye Z., Cao C., Hu Q., Kim J.,
RA Larkin D.M., Auvil L., Capitanu B., Ma J., Lewin H.A., Qian X., Lang Y.,
RA Zhou R., Wang L., Wang K., Xia J., Liao S., Pan S., Lu X., Hou H., Wang Y.,
RA Zang X., Yin Y., Ma H., Zhang J., Wang Z., Zhang Y., Zhang D., Yonezawa T.,
RA Hasegawa M., Zhong Y., Liu W., Zhang Y., Huang Z., Zhang S., Long R.,
RA Yang H., Wang J., Lenstra J.A., Cooper D.N., Wu Y., Wang J., Shi P.,
RA Wang J., Liu J.;
RT "The yak genome and adaptation to life at high altitude.";
RL Nat. Genet. 44:946-949(2012).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00320}.
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DR EMBL; JH883538; ELR46283.1; -; Genomic_DNA.
DR AlphaFoldDB; L8HR19; -.
DR STRING; 72004.ENSBMUP00000023957; -.
DR Proteomes; UP000011080; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.10.60; Homeodomain-like; 2.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR006600; HTH_CenpB_DNA-bd_dom.
DR InterPro; IPR007889; HTH_Psq.
DR PANTHER; PTHR19303:SF26; TIGGER TRANSPOSABLE ELEMENT-DERIVED PROTEIN 1; 1.
DR PANTHER; PTHR19303; TRANSPOSON; 1.
DR Pfam; PF04218; CENP-B_N; 1.
DR Pfam; PF03221; HTH_Tnp_Tc5; 1.
DR SMART; SM00674; CENPB; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 2.
DR PROSITE; PS51253; HTH_CENPB; 1.
DR PROSITE; PS50960; HTH_PSQ; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00320};
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00320};
KW Reference proteome {ECO:0000313|Proteomes:UP000011080}.
FT DOMAIN 13..64
FT /note="HTH psq-type"
FT /evidence="ECO:0000259|PROSITE:PS50960"
FT DOMAIN 78..157
FT /note="HTH CENPB-type"
FT /evidence="ECO:0000259|PROSITE:PS51253"
FT DNA_BIND 40..60
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00320"
FT NON_TER 189
FT /evidence="ECO:0000313|EMBL:ELR46283.1"
SQ SEQUENCE 189 AA; 21377 MW; DE014A653CF23BF4 CRC64;
MSGSKRKSSG DVAGTAKKRH AITMETKVKI IERVERGEKM TDVARSFNLN RSTIGTIVKN
KDKILEHVKS AVSMMSTIIS KRRGKAMEEM EKLLSVWLQD QHQRRAPLNI MLIQEKAKSL
YEDLKKKYGE ESDGPSFNAS CGWFYRFKAR ANLHSVKVSD EAVSADVAAA REFPEILREI
IDEGAYLPE
//
