ID L8HZE9_9CETA Unreviewed; 132 AA.
AC L8HZE9;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=FXYD domain-containing ion transport regulator {ECO:0000256|RuleBase:RU364131};
GN ORFNames=M91_06550 {ECO:0000313|EMBL:ELR48694.1};
OS Bos mutus (wild yak).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=72004 {ECO:0000313|EMBL:ELR48694.1, ECO:0000313|Proteomes:UP000011080};
RN [1] {ECO:0000313|EMBL:ELR48694.1, ECO:0000313|Proteomes:UP000011080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=yakQH1 {ECO:0000313|Proteomes:UP000011080};
RX PubMed=22751099; DOI=10.1038/ng.2343;
RA Qiu Q., Zhang G., Ma T., Qian W., Wang J., Ye Z., Cao C., Hu Q., Kim J.,
RA Larkin D.M., Auvil L., Capitanu B., Ma J., Lewin H.A., Qian X., Lang Y.,
RA Zhou R., Wang L., Wang K., Xia J., Liao S., Pan S., Lu X., Hou H., Wang Y.,
RA Zang X., Yin Y., Ma H., Zhang J., Wang Z., Zhang Y., Zhang D., Yonezawa T.,
RA Hasegawa M., Zhong Y., Liu W., Zhang Y., Huang Z., Zhang S., Long R.,
RA Yang H., Wang J., Lenstra J.A., Cooper D.N., Wu Y., Wang J., Shi P.,
RA Wang J., Liu J.;
RT "The yak genome and adaptation to life at high altitude.";
RL Nat. Genet. 44:946-949(2012).
CC -!- SIMILARITY: Belongs to the FXYD family. {ECO:0000256|ARBA:ARBA00005948,
CC ECO:0000256|RuleBase:RU364131}.
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DR EMBL; JH882623; ELR48694.1; -; Genomic_DNA.
DR AlphaFoldDB; L8HZE9; -.
DR STRING; 72004.ENSBMUP00000017166; -.
DR Proteomes; UP000011080; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0099106; F:ion channel regulator activity; IEA:InterPro.
DR GO; GO:0071805; P:potassium ion transmembrane transport; IEA:InterPro.
DR GO; GO:0043269; P:regulation of monoatomic ion transport; IEA:InterPro.
DR CDD; cd20322; FXYD4; 1.
DR Gene3D; 1.20.5.780; Single helix bin; 1.
DR InterPro; IPR047283; FXYD4.
DR InterPro; IPR000272; Ion-transport_regulator_FXYD.
DR PANTHER; PTHR14132:SF10; FXYD DOMAIN-CONTAINING ION TRANSPORT REGULATOR 4; 1.
DR PANTHER; PTHR14132; SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT GAMMA; 1.
DR Pfam; PF02038; ATP1G1_PLM_MAT8; 1.
PE 3: Inferred from homology;
KW Ion transport {ECO:0000256|RuleBase:RU364131};
KW Membrane {ECO:0000256|RuleBase:RU364131};
KW Reference proteome {ECO:0000313|Proteomes:UP000011080};
KW Transmembrane {ECO:0000256|RuleBase:RU364131};
KW Transmembrane helix {ECO:0000256|RuleBase:RU364131};
KW Transport {ECO:0000256|RuleBase:RU364131}.
FT TRANSMEM 88..108
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364131"
SQ SEQUENCE 132 AA; 14534 MW; 49F26181856A7772 CRC64;
MDEQTGWKRL SLHGAWEAFI PQIEDQPWVS PLPLQHLHPK PQTGPACRCV MEGVTRALLL
LLAGLPVLEA NDVIDKDSPF YYDWEGLQLG GMICAGLMCI AGLLFALSGK CKCKNKQKHG
LCQYLLSTGL VS
//
