ID L8IBC3_9CETA Unreviewed; 307 AA.
AC L8IBC3;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Peroxisomal membrane protein PMP34 {ECO:0000313|EMBL:ELR53755.1};
GN ORFNames=M91_18864 {ECO:0000313|EMBL:ELR53755.1};
OS Bos mutus (wild yak).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=72004 {ECO:0000313|EMBL:ELR53755.1, ECO:0000313|Proteomes:UP000011080};
RN [1] {ECO:0000313|EMBL:ELR53755.1, ECO:0000313|Proteomes:UP000011080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=yakQH1 {ECO:0000313|Proteomes:UP000011080};
RX PubMed=22751099; DOI=10.1038/ng.2343;
RA Qiu Q., Zhang G., Ma T., Qian W., Wang J., Ye Z., Cao C., Hu Q., Kim J.,
RA Larkin D.M., Auvil L., Capitanu B., Ma J., Lewin H.A., Qian X., Lang Y.,
RA Zhou R., Wang L., Wang K., Xia J., Liao S., Pan S., Lu X., Hou H., Wang Y.,
RA Zang X., Yin Y., Ma H., Zhang J., Wang Z., Zhang Y., Zhang D., Yonezawa T.,
RA Hasegawa M., Zhong Y., Liu W., Zhang Y., Huang Z., Zhang S., Long R.,
RA Yang H., Wang J., Lenstra J.A., Cooper D.N., Wu Y., Wang J., Shi P.,
RA Wang J., Liu J.;
RT "The yak genome and adaptation to life at high altitude.";
RL Nat. Genet. 44:946-949(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Peroxisome
CC membrane {ECO:0000256|ARBA:ARBA00004585}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004585}.
CC -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) family.
CC {ECO:0000256|ARBA:ARBA00006375, ECO:0000256|RuleBase:RU000488}.
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DR EMBL; JH881533; ELR53755.1; -; Genomic_DNA.
DR RefSeq; XP_005899522.1; XM_005899460.2.
DR AlphaFoldDB; L8IBC3; -.
DR STRING; 72004.ENSBMUP00000005941; -.
DR Ensembl; ENSBMUT00000006898; ENSBMUP00000005941; ENSBMUG00000004666.
DR GeneID; 102269562; -.
DR KEGG; bom:102269562; -.
DR CTD; 10478; -.
DR OrthoDB; 3670854at2759; -.
DR Proteomes; UP000011080; Unassembled WGS sequence.
DR GO; GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015217; F:ADP transmembrane transporter activity; IEA:Ensembl.
DR GO; GO:0080122; F:AMP transmembrane transporter activity; IEA:Ensembl.
DR GO; GO:0005347; F:ATP transmembrane transporter activity; IEA:Ensembl.
DR GO; GO:0015228; F:coenzyme A transmembrane transporter activity; IEA:Ensembl.
DR GO; GO:0015230; F:FAD transmembrane transporter activity; IEA:Ensembl.
DR GO; GO:0044610; F:FMN transmembrane transporter activity; IEA:Ensembl.
DR GO; GO:0051724; F:NAD transmembrane transporter activity; IEA:Ensembl.
DR GO; GO:0051087; F:protein-folding chaperone binding; IEA:Ensembl.
DR GO; GO:0006635; P:fatty acid beta-oxidation; IEA:Ensembl.
DR GO; GO:0015908; P:fatty acid transport; IEA:Ensembl.
DR Gene3D; 1.50.40.10; Mitochondrial carrier domain; 2.
DR InterPro; IPR002067; Mit_carrier.
DR InterPro; IPR018108; Mitochondrial_sb/sol_carrier.
DR InterPro; IPR023395; Mt_carrier_dom_sf.
DR PANTHER; PTHR45939:SF5; PEROXISOMAL MEMBRANE PROTEIN PMP34; 1.
DR PANTHER; PTHR45939; PEROXISOMAL MEMBRANE PROTEIN PMP34-RELATED; 1.
DR Pfam; PF00153; Mito_carr; 3.
DR PRINTS; PR00926; MITOCARRIER.
DR SUPFAM; SSF103506; Mitochondrial carrier; 1.
DR PROSITE; PS50920; SOLCAR; 3.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU00282}; Peroxisome {ECO:0000256|ARBA:ARBA00023140};
KW Reference proteome {ECO:0000313|Proteomes:UP000011080};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU00282};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU000488}.
FT TRANSMEM 12..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 67..85
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 105..125
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 200..221
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 278..301
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 7..92
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REPEAT 99..192
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REPEAT 200..294
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
SQ SEQUENCE 307 AA; 34554 MW; 06BBADFED38BD7AD CRC64;
MSSVLSYESL VHAVAGAVGS MTAMTVFFPL DTARLRLQVD EKRKSKTTHM VLLEIIKEEG
LLAPYRGWFP VISSLCCSNF VYFYTFNSLK AVWVKGQHST TGKDLVVGFV AGVVNVLLTT
PLWVVNTRLK LQGAKFRNED IVPTNYSGII DAFHQIIRDE GILALWNGTF PSLLLVFNPA
IQFMFYEGLK RQLLKKRTKL SSLDVFLIGA IAKAVATTVT YPMQTVQSIL RFGRHRLNPE
NRTLGSLRNI LYLLHQRVRR FGIAGLYKGL EAKLLQTVLT AALMFLVYEK LMAATFMVMG
LKSTRKH
//
