ID L8IFX3_9CETA Unreviewed; 574 AA.
AC L8IFX3;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Interleukin-10 receptor subunit alpha {ECO:0000313|EMBL:ELR55405.1};
DE Flags: Fragment;
GN ORFNames=M91_09746 {ECO:0000313|EMBL:ELR55405.1};
OS Bos mutus (wild yak).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=72004 {ECO:0000313|EMBL:ELR55405.1, ECO:0000313|Proteomes:UP000011080};
RN [1] {ECO:0000313|EMBL:ELR55405.1, ECO:0000313|Proteomes:UP000011080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=yakQH1 {ECO:0000313|Proteomes:UP000011080};
RX PubMed=22751099; DOI=10.1038/ng.2343;
RA Qiu Q., Zhang G., Ma T., Qian W., Wang J., Ye Z., Cao C., Hu Q., Kim J.,
RA Larkin D.M., Auvil L., Capitanu B., Ma J., Lewin H.A., Qian X., Lang Y.,
RA Zhou R., Wang L., Wang K., Xia J., Liao S., Pan S., Lu X., Hou H., Wang Y.,
RA Zang X., Yin Y., Ma H., Zhang J., Wang Z., Zhang Y., Zhang D., Yonezawa T.,
RA Hasegawa M., Zhong Y., Liu W., Zhang Y., Huang Z., Zhang S., Long R.,
RA Yang H., Wang J., Lenstra J.A., Cooper D.N., Wu Y., Wang J., Shi P.,
RA Wang J., Liu J.;
RT "The yak genome and adaptation to life at high altitude.";
RL Nat. Genet. 44:946-949(2012).
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DR EMBL; JH881271; ELR55405.1; -; Genomic_DNA.
DR AlphaFoldDB; L8IFX3; -.
DR STRING; 72004.ENSBMUP00000016554; -.
DR Proteomes; UP000011080; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR20859; INTERFERON/INTERLEUKIN RECEPTOR; 1.
DR PANTHER; PTHR20859:SF88; INTERLEUKIN-10 RECEPTOR SUBUNIT ALPHA; 1.
DR Pfam; PF01108; Tissue_fac; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius}; Receptor {ECO:0000313|EMBL:ELR55405.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000011080};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..574
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003991777"
FT TRANSMEM 231..255
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 15..107
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|Pfam:PF01108"
FT REGION 302..433
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 449..468
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 305..331
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 353..367
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 574
FT /evidence="ECO:0000313|EMBL:ELR55405.1"
SQ SEQUENCE 574 AA; 63342 MW; 9CE6A70C2DA3C1A9 CRC64;
WEALLPLVLT LSFLLIELPR PPSAWFEAEF FHHVLYWTPI PNQSESTYYE VELLRYGVEP
TSWKSIQRCS QMLMMSCDVT VETLDLYRSN GYRARVRAVD GSQRSNWTSP NTRFSMDEVT
LTVASVKLEV HNGNIVGAIQ LPRPEVAPEG DTYENIFHNF REYQIEVRKA PGHYESHGKV
KNESFKLPIP RGVGEFCIRV KPSVGSRVNK EVWSKEECIL LTSQYFTVTN ISIFLTFVLL
LYGALAFCLT FQLYVRRRGK LPAVLVFKKP SPFNLISQFS HPETQDTVHT LDEEAFPKVT
PELRNSDMHG STDSGFGSAK PSLQTEEPQF LLPASDPQAG GTLEKGMPQE LENSCGSAGS
SNSADSGICL PDPRLCPGTE PSWEPQVGSD SRDREDSGIG LVQNSRGQPE DAQGGSASGH
VSPLGPEEPV EEDSVAGAFQ GYLKQTQCPE EKAAQAGGLE EESSSTEDLD PQFRTCLDTE
AGWPLPALAK GYVQQDPPEM ILAPLQTPEE QWDRPTEDWS FLGLTSCGDL GTSDWSFAHD
LAPLDCVPAP GGLLGSFDSD LVTLPLITSL QSNE
//
