ID L8J1W4_9CETA Unreviewed; 176 AA.
AC L8J1W4;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 24-JAN-2024, entry version 41.
DE RecName: Full=NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 {ECO:0000256|ARBA:ARBA00014109};
DE AltName: Full=Complex I-PDSW {ECO:0000256|ARBA:ARBA00030372};
DE AltName: Full=NADH-ubiquinone oxidoreductase PDSW subunit {ECO:0000256|ARBA:ARBA00032549};
GN ORFNames=E5288_WYG009147 {ECO:0000313|EMBL:MXQ80834.1}, M91_08741
GN {ECO:0000313|EMBL:ELR62860.1};
OS Bos mutus (wild yak).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=72004 {ECO:0000313|EMBL:ELR62860.1, ECO:0000313|Proteomes:UP000011080};
RN [1] {ECO:0000313|EMBL:ELR62860.1, ECO:0000313|Proteomes:UP000011080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=yakQH1 {ECO:0000313|Proteomes:UP000011080}, and YakQH1
RC {ECO:0000313|EMBL:ELR62860.1};
RX PubMed=22751099; DOI=10.1038/ng.2343;
RA Qiu Q., Zhang G., Ma T., Qian W., Wang J., Ye Z., Cao C., Hu Q., Kim J.,
RA Larkin D.M., Auvil L., Capitanu B., Ma J., Lewin H.A., Qian X., Lang Y.,
RA Zhou R., Wang L., Wang K., Xia J., Liao S., Pan S., Lu X., Hou H., Wang Y.,
RA Zang X., Yin Y., Ma H., Zhang J., Wang Z., Zhang Y., Zhang D., Yonezawa T.,
RA Hasegawa M., Zhong Y., Liu W., Zhang Y., Huang Z., Zhang S., Long R.,
RA Yang H., Wang J., Lenstra J.A., Cooper D.N., Wu Y., Wang J., Shi P.,
RA Wang J., Liu J.;
RT "The yak genome and adaptation to life at high altitude.";
RL Nat. Genet. 44:946-949(2012).
RN [2] {ECO:0000313|EMBL:MXQ80834.1, ECO:0000313|Proteomes:UP000322234}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WY2019 {ECO:0000313|EMBL:MXQ80834.1};
RC TISSUE=Blood {ECO:0000313|EMBL:MXQ80834.1};
RA Liu Y.;
RT "The sequence and de novo assembly of the wild yak genome.";
RL Submitted (OCT-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Accessory subunit that is involved in the functional assembly
CC of the mitochondrial respiratory chain complex I. Complex I has an NADH
CC dehydrogenase activity with ubiquinone as an immediate electron
CC acceptor and mediates the transfer of electrons from NADH to the
CC respiratory chain. {ECO:0000256|ARBA:ARBA00024857}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC {ECO:0000256|ARBA:ARBA00004443}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004443}; Matrix side
CC {ECO:0000256|ARBA:ARBA00004443}.
CC -!- SIMILARITY: Belongs to the complex I NDUFB10 subunit family.
CC {ECO:0000256|ARBA:ARBA00008317}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JH880269; ELR62860.1; -; Genomic_DNA.
DR EMBL; VBQZ03000005; MXQ80834.1; -; Genomic_DNA.
DR RefSeq; XP_005886873.1; XM_005886811.1.
DR AlphaFoldDB; L8J1W4; -.
DR SMR; L8J1W4; -.
DR STRING; 72004.ENSBMUP00000023910; -.
DR Ensembl; ENSBMUT00000027529; ENSBMUP00000023910; ENSBMUG00000017948.
DR GeneID; 102282668; -.
DR KEGG; bom:102282668; -.
DR CTD; 4716; -.
DR OrthoDB; 2871654at2759; -.
DR Proteomes; UP000011080; Unassembled WGS sequence.
DR Proteomes; UP000322234; Unassembled WGS sequence.
DR GO; GO:0005747; C:mitochondrial respiratory chain complex I; IEA:Ensembl.
DR GO; GO:0032981; P:mitochondrial respiratory chain complex I assembly; IEA:Ensembl.
DR InterPro; IPR019377; NADH_UbQ_OxRdtase_su10.
DR InterPro; IPR039993; NDUFB10.
DR PANTHER; PTHR13094:SF1; NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 10; 1.
DR PANTHER; PTHR13094; NADH-UBIQUINONE OXIDOREDUCTASE PDSW SUBUNIT; 1.
DR Pfam; PF10249; NDUFB10; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Electron transport {ECO:0000256|ARBA:ARBA00022982};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00022792};
KW Reference proteome {ECO:0000313|Proteomes:UP000011080};
KW Respiratory chain {ECO:0000256|ARBA:ARBA00022660};
KW Transport {ECO:0000256|ARBA:ARBA00022448};
KW Ubiquinone {ECO:0000313|EMBL:ELR62860.1}.
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 122..173
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 176 AA; 20965 MW; F4409C8D49AE0AB4 CRC64;
MPDSWDKDVY PEPPRRTPAP SPQTSLPNPI TYLTKAFDLL VDRPVTLVRE FIERQHAKNK
YYYYHREFRR VPDITECQEK DVLCMFEAEM QWRRDYKVDQ EIVNIIQERL KACQQREGES
HRQNCAKELE QFTQVVKAYQ DRYHDLGAHY SARKCLAKQK QRMLAERKAA KEAAAA
//
