ID L8LJ98_9CHRO Unreviewed; 730 AA.
AC L8LJ98;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Anaerobic dehydrogenase, typically selenocysteine-containing {ECO:0000313|EMBL:ELR97608.1};
GN ORFNames=GLO73106DRAFT_00014200 {ECO:0000313|EMBL:ELR97608.1};
OS Gloeocapsa sp. PCC 73106.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Chroococcales; Chroococcaceae; Gloeocapsa.
OX NCBI_TaxID=102232 {ECO:0000313|EMBL:ELR97608.1, ECO:0000313|Proteomes:UP000011180};
RN [1] {ECO:0000313|EMBL:ELR97608.1, ECO:0000313|Proteomes:UP000011180}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 73106 {ECO:0000313|EMBL:ELR97608.1,
RC ECO:0000313|Proteomes:UP000011180};
RX PubMed=23277585; DOI=10.1073/pnas.1217107110;
RA Shih P.M., Wu D., Latifi A., Axen S.D., Fewer D.P., Talla E., Calteau A.,
RA Cai F., Tandeau de Marsac N., Rippka R., Herdman M., Sivonen K.,
RA Coursin T., Laurent T., Goodwin L., Nolan M., Davenport K.W., Han C.S.,
RA Rubin E.M., Eisen J.A., Woyke T., Gugger M., Kerfeld C.A.;
RT "Improving the coverage of the cyanobacterial phylum using diversity-driven
RT genome sequencing.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:1053-1058(2013).
CC -!- COFACTOR:
CC Name=Mo-bis(molybdopterin guanine dinucleotide);
CC Xref=ChEBI:CHEBI:60539; Evidence={ECO:0000256|ARBA:ARBA00001942};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- PATHWAY: Nitrogen metabolism. {ECO:0000256|ARBA:ARBA00004909}.
CC -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC oxidoreductase family. NasA/NapA/NarB subfamily.
CC {ECO:0000256|ARBA:ARBA00008747}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELR97608.1}.
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DR EMBL; ALVY01000208; ELR97608.1; -; Genomic_DNA.
DR RefSeq; WP_006529589.1; NZ_ALVY01000208.1.
DR AlphaFoldDB; L8LJ98; -.
DR STRING; 102232.GLO73106DRAFT_00014200; -.
DR PATRIC; fig|102232.3.peg.2606; -.
DR eggNOG; COG0243; Bacteria.
DR OrthoDB; 9803192at2; -.
DR Proteomes; UP000011180; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0042128; P:nitrate assimilation; IEA:UniProtKB-KW.
DR CDD; cd02791; MopB_CT_Nitrate-R-NapA-like; 1.
DR CDD; cd02754; MopB_Nitrate-R-NapA-like; 1.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 3.40.50.740; -; 1.
DR Gene3D; 2.20.25.90; ADC-like domains; 1.
DR Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR InterPro; IPR041957; CT_Nitrate-R-NapA-like.
DR InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR PANTHER; PTHR43105:SF9; NITRATE REDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G15190)-RELATED; 1.
DR PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR Pfam; PF04879; Molybdop_Fe4S4; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF01568; Molydop_binding; 1.
DR PIRSF; PIRSF000144; CbbBc; 2.
DR SMART; SM00926; Molybdop_Fe4S4; 1.
DR SUPFAM; SSF50692; ADC-like; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Molybdenum {ECO:0000256|ARBA:ARBA00022505};
KW Nitrate assimilation {ECO:0000256|ARBA:ARBA00023063};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000011180}.
FT DOMAIN 2..70
FT /note="4Fe-4S Mo/W bis-MGD-type"
FT /evidence="ECO:0000259|PROSITE:PS51669"
SQ SEQUENCE 730 AA; 81141 MW; 3B2FDC841EFA0894 CRC64;
MVDSVKTLCP YCGVGCGLEV SSPRFSGTGN PTDEQGNPIW KVTGDRAHPS SQGMVCIKGA
TITESLYKNR LEYPMMRDSL EEPFRRCSWD QALTRIVDHI KLLRSTQGAD AICMYGSGQF
QTEDYYIAQK LLKGCLGTNN FDANSRLCMS SAVSAYIKSF GSDGPPCCYE DLEHTDCAFL
IGTNTAECHP IVFNRLQKYL RKNRKARLIV VDPRTTKTAE AAHLHLAIKP GTDIDLLNGI
AHILLEWGEI NTFFIDECTK GFYEYAEVIR HYPPELVAAK CGISVPQLKK AARYWAKANR
VLSLWSMGIN QSSEGTAKAR TLINLHLMTG NIGKPGAGPF SLTGQPNAMG GREAGGLSHL
LPGYRSVLNA EHRRDVEQFW KLEPGRISPT PGRDAWRMIT GLETGDVGLL WIAATNPAVS
MPDLSRTKAA LLKSPLTVYQ DAYYPTETSA YAHILLPAAQ WSEKTGTMTN SERVVTLCPQ
FRLPPGEAKA DWQIFAEVGK RLGFTSQFNF KDSAEVYAEF VQLTRDRFCD LTGISHQALL
RSGPIQWPCP QDHSRESKRL YTDFRFPTPD GRAQFAAYHS KGLAEPPDPE YPFILTVGRL
YGHWHTQTRT GHIPKITKMY PYPRLEIHPQ DAARINIADG EWLEVRSRRG KACFLTQITR
AITPGTVFVP MHWGALWAQH AEANLLTHSE ACPISLEPEL KACAVQLIPV LASSATLIDV
SELNSKLANF
//
