ID L8P7Y5_STRVR Unreviewed; 577 AA.
AC L8P7Y5;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE SubName: Full=Putative Precorrin methylase {ECO:0000313|EMBL:ELS52279.1};
GN ORFNames=STVIR_6793 {ECO:0000313|EMBL:ELS52279.1};
OS Streptomyces viridochromogenes Tue57.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1160705 {ECO:0000313|EMBL:ELS52279.1, ECO:0000313|Proteomes:UP000011205};
RN [1] {ECO:0000313|EMBL:ELS52279.1, ECO:0000313|Proteomes:UP000011205}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tue57 {ECO:0000313|EMBL:ELS52279.1,
RC ECO:0000313|Proteomes:UP000011205};
RX PubMed=23788550;
RA Gruning B.A., Erxleben A., Hahnlein A., Gunther S.;
RT "Draft Genome Sequence of Streptomyces viridochromogenes Strain Tu57,
RT Producer of Avilamycin.";
RL Genome Announc. 1:E00384-13(2013).
CC -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004953}.
CC -!- SIMILARITY: Belongs to the precorrin methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00005879}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELS52279.1}.
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DR EMBL; AMLP01000213; ELS52279.1; -; Genomic_DNA.
DR RefSeq; WP_004002260.1; NZ_AMLP01000213.1.
DR AlphaFoldDB; L8P7Y5; -.
DR PATRIC; fig|1160705.3.peg.6710; -.
DR UniPathway; UPA00148; -.
DR Proteomes; UP000011205; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd11646; Precorrin_3B_C17_MT; 1.
DR Gene3D; 3.40.50.11220; -; 1.
DR Gene3D; 3.30.420.180; CobE/GbiG C-terminal domain; 1.
DR InterPro; IPR000878; 4pyrrol_Mease.
DR InterPro; IPR035996; 4pyrrol_Methylase_sf.
DR InterPro; IPR014777; 4pyrrole_Mease_sub1.
DR InterPro; IPR014776; 4pyrrole_Mease_sub2.
DR InterPro; IPR021744; CbiG_N.
DR InterPro; IPR006363; Cbl_synth_CobJ/CibH_dom.
DR InterPro; IPR002750; CobE/GbiG_C.
DR InterPro; IPR036518; CobE/GbiG_C_sf.
DR InterPro; IPR038029; GbiG_N_sf.
DR NCBIfam; TIGR01466; cobJ_cbiH; 1.
DR PANTHER; PTHR47036; COBALT-FACTOR III C(17)-METHYLTRANSFERASE-RELATED; 1.
DR PANTHER; PTHR47036:SF1; COBALT-FACTOR III C(17)-METHYLTRANSFERASE-RELATED; 1.
DR Pfam; PF01890; CbiG_C; 1.
DR Pfam; PF11760; CbiG_N; 1.
DR Pfam; PF00590; TP_methylase; 1.
DR SUPFAM; SSF159672; CbiG N-terminal domain-like; 1.
DR SUPFAM; SSF159664; CobE/GbiG C-terminal domain-like; 1.
DR SUPFAM; SSF53790; Tetrapyrrole methylase; 1.
PE 3: Inferred from homology;
KW Cobalamin biosynthesis {ECO:0000256|ARBA:ARBA00022573};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:ELS52279.1};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 36..116
FT /note="Cobalamin synthesis G N-terminal"
FT /evidence="ECO:0000259|Pfam:PF11760"
FT DOMAIN 191..312
FT /note="CobE/GbiG C-terminal"
FT /evidence="ECO:0000259|Pfam:PF01890"
FT DOMAIN 320..525
FT /note="Tetrapyrrole methylase"
FT /evidence="ECO:0000259|Pfam:PF00590"
FT REGION 557..577
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 577 AA; 59186 MW; 9B619C616E80BCC7 CRC64;
MIGLISATAA GAAARDRLAA AWPERTRVYE GPVKDAVRRA FAECEQLVCF LATGAVVRLL
APLLADKAAD PGVVCVDEGG RFAVSLVGGH GGGANELARE VGDLLGAEPV VTTATDAVGL
PGLDMLGFPV EGDVAGVSRA MLDGAAVALK AEVAWPLPPL RAGAEGAYTI RLTDRLVEPA
EREVVLRPPS LVVGVGASKG APADEVLGLI ERTLADAGLS PASLAELATV DAKAGEPGIV
EAAARLGVPL VTHSAEELAA VEVPNPSDAP LTAVGTPSVA EAAALVRGGE LLVPKRKSER
ADGRPAMATC AVVRRPGRGR LAVVGLGPGA RDLLTPRAKA ELERASVLVG LDQYVDQIRD
LLRPGTRILE SGLGAEEERA RTAVAEARKG QAVALIGSGD AGVYAMASPA LAEASDDIDV
IGVPGVTAAL AAAAILGAPL GHDHVSISLS DLHTPWEVIE RRVRAAAEAD IVVTFYNPRS
RGRDWQLPKA LAILAEHREP TTPVGVVRNA SRPDESARLT ALGALDPATV DMMTVVTVGN
TATRDIAGRM VTPRGYRWQE AASTSGSAAG PRQGDGR
//
