ID L8PBF2_STRVR Unreviewed; 531 AA.
AC L8PBF2;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN ORFNames=STVIR_5571 {ECO:0000313|EMBL:ELS53503.1};
OS Streptomyces viridochromogenes Tue57.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1160705 {ECO:0000313|EMBL:ELS53503.1, ECO:0000313|Proteomes:UP000011205};
RN [1] {ECO:0000313|EMBL:ELS53503.1, ECO:0000313|Proteomes:UP000011205}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tue57 {ECO:0000313|EMBL:ELS53503.1,
RC ECO:0000313|Proteomes:UP000011205};
RX PubMed=23788550;
RA Gruning B.A., Erxleben A., Hahnlein A., Gunther S.;
RT "Draft Genome Sequence of Streptomyces viridochromogenes Strain Tu57,
RT Producer of Avilamycin.";
RL Genome Announc. 1:E00384-13(2013).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC {ECO:0000256|ARBA:ARBA00006285}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELS53503.1}.
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DR EMBL; AMLP01000166; ELS53503.1; -; Genomic_DNA.
DR AlphaFoldDB; L8PBF2; -.
DR PATRIC; fig|1160705.3.peg.5507; -.
DR Proteomes; UP000011205; Unassembled WGS sequence.
DR GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd06568; GH20_SpHex_like; 1.
DR Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR InterPro; IPR015883; Glyco_hydro_20_cat.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR029018; Hex-like_dom2.
DR InterPro; IPR015882; HEX_bac_N.
DR PANTHER; PTHR22600; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR22600:SF21; BETA-HEXOSAMINIDASE A; 1.
DR Pfam; PF00728; Glyco_hydro_20; 1.
DR Pfam; PF02838; Glyco_hydro_20b; 1.
DR PRINTS; PR00738; GLHYDRLASE20.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..31
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 32..531
FT /note="beta-N-acetylhexosaminidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5039329047"
FT DOMAIN 43..170
FT /note="Beta-hexosaminidase bacterial type N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02838"
FT DOMAIN 174..493
FT /note="Glycoside hydrolase family 20 catalytic"
FT /evidence="ECO:0000259|Pfam:PF00728"
FT ACT_SITE 337
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ SEQUENCE 531 AA; 57547 MW; 86C8167D2C7FC25C CRC64;
MRRHHRTTPR TTRILGSLLL VMAAGAFTLG AAPASGEAIP LTQVVPAPAS VTAGGSPYRI
TDATRIRVDD SREARRVGEY LAGILRPSTG YPLTVTSHGR GGIRLRLAQG PFGAEGYRLD
SGRSGVTITA ARPAGLFHGV QTLRQLLPAA VEKDSVQPGP WLVAGGTITD TPRYGWRGAM
LDVSRHFFTV DQVKRYIDQL ALYKINKLHL HLSDDQGWRI AIDSWPRLAA YGGSTQVGGG
PGGHYTKADY QEIVRYAASR YLEVVPEIDM PGHTNAALAS YAELNCDGVA PPLYTGTDVG
FSSLCVGKEI TYDFVDDVIR ELAALTPGEY LHIGGDEAHS TSHEDYVKFM DRVQPIVAEY
GKTVVGWHQL TGATPAKGAL AQYWGLDGTS DEEKAQAVKA AQNGTGLILS PADRIYLDMK
YTADTPLGLD WAGLVEVKRS YDWDPGNYLP GAPSSAIRGV EAPLWTETIT KSADIEYMAF
PRLAGVAELG WSPASTHDWE DYKVRLAAQG PRWDALGIGY YQSPQIPWPA R
//
