ID L8PNE7_STRVR Unreviewed; 958 AA.
AC L8PNE7;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=beta-galactosidase {ECO:0000256|ARBA:ARBA00012756};
DE EC=3.2.1.23 {ECO:0000256|ARBA:ARBA00012756};
DE AltName: Full=Lactase {ECO:0000256|ARBA:ARBA00032230};
GN ORFNames=STVIR_1475 {ECO:0000313|EMBL:ELS57568.1};
OS Streptomyces viridochromogenes Tue57.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1160705 {ECO:0000313|EMBL:ELS57568.1, ECO:0000313|Proteomes:UP000011205};
RN [1] {ECO:0000313|EMBL:ELS57568.1, ECO:0000313|Proteomes:UP000011205}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tue57 {ECO:0000313|EMBL:ELS57568.1,
RC ECO:0000313|Proteomes:UP000011205};
RX PubMed=23788550;
RA Gruning B.A., Erxleben A., Hahnlein A., Gunther S.;
RT "Draft Genome Sequence of Streptomyces viridochromogenes Strain Tu57,
RT Producer of Avilamycin.";
RL Genome Announc. 1:E00384-13(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing beta-D-galactose residues
CC in beta-D-galactosides.; EC=3.2.1.23;
CC Evidence={ECO:0000256|ARBA:ARBA00001412};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELS57568.1}.
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DR EMBL; AMLP01000051; ELS57568.1; -; Genomic_DNA.
DR RefSeq; WP_003996820.1; NZ_AMLP01000051.1.
DR AlphaFoldDB; L8PNE7; -.
DR PATRIC; fig|1160705.3.peg.1470; -.
DR Proteomes; UP000011205; Unassembled WGS sequence.
DR GO; GO:0009341; C:beta-galactosidase complex; IEA:InterPro.
DR GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR GO; GO:1901575; P:organic substance catabolic process; IEA:UniProt.
DR Gene3D; 2.70.98.10; -; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR004199; B-gal_small/dom_5.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR014718; GH-type_carb-bd.
DR InterPro; IPR006101; Glyco_hydro_2.
DR InterPro; IPR023232; Glyco_hydro_2_AS.
DR InterPro; IPR006103; Glyco_hydro_2_cat.
DR InterPro; IPR023230; Glyco_hydro_2_CS.
DR InterPro; IPR006104; Glyco_hydro_2_N.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR032312; LacZ_4.
DR PANTHER; PTHR46323; BETA-GALACTOSIDASE; 1.
DR PANTHER; PTHR46323:SF2; BETA-GALACTOSIDASE; 1.
DR Pfam; PF02929; Bgal_small_N; 1.
DR Pfam; PF02836; Glyco_hydro_2_C; 1.
DR Pfam; PF02837; Glyco_hydro_2_N; 1.
DR Pfam; PF16353; LacZ_4; 1.
DR PRINTS; PR00132; GLHYDRLASE2.
DR SMART; SM01038; Bgal_small_N; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 2.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS00719; GLYCOSYL_HYDROL_F2_1; 1.
DR PROSITE; PS00608; GLYCOSYL_HYDROL_F2_2; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 696..955
FT /note="Beta galactosidase small chain/"
FT /evidence="ECO:0000259|SMART:SM01038"
SQ SEQUENCE 958 AA; 106234 MW; BF44F9AD460C6CD5 CRC64;
MSFRTTTDVT YVEDVSPGRG ALPPRAWYAS SDAKSLSLNG SWRLRVSATA DAEDDSFAEE
GYDAGDWAEV TVPGHWVLQG DGAFGSPAYT NHLYPFPVDP PRVPTENPTG DHLRFFDLPA
DWPAPGEGGA VLRFDGVESC ARVWLNGTDI GEFKGSRLPH EFAVGHLLKP TGNVLAVRVH
QWSAGSYLED QDQWWLPGIF RDVTLLHRPA GSVLDFFVHA DYDHTTGEGT LRVDSDVDGR
VSVPALDIDV ATGESVTVPV EPWSAETPKL YDGELVTAGE RVPLRIGFRT VVLEDGLIKV
NGRAILFKGV NRHEWHPEKG RALDLETMRE DVLLMKRHNL NAVRTSHYPP HPAFLDLCDE
YGLWVIDECD LETHGFTEQA WRDNPVDDDR WTPALLDRAA RMVERDKNHP SIVFWSLGNE
AGTGRGLTAM AEWIHGRDSS RLVHYEGDWD CRDTDVYSRM YAFHDEVEKI GQKLDGGTHK
RRELPFIQCE YGHAMGNGPG GLADYQKLFE SYDRLQGGFI WEWIDHGIKH PELGYAYGGD
FGEELHDGNF VCDGLIFPDR TPSPGLVEYK KVIEPVRVEG DCADGTVRVT NKYDFADLSG
LAFEWAYQVD GETVEAGALS VPDLAPGESA DLKLPEPPAH GTGGETQWTV RALLAADTAW
APKGHVVAWG QFPVSGRQSP SVAASDRPAA SEKLITLGPA SFDARTGALK TVGGVEVTAP
RLDVWRAPTD NDDGAEWQTD TRYGMLWRKY GLHRMRHRLD AVEVSDDALT VRTRVAPAAW
EFGLATVYRW TSDGERLKLT VSVTPDGDWQ VPLPRLGIRL GLPQADAVRW FGGGPGEAYP
DTRLASMIGR WHSTVDELQT PYVRPQENGA RADVRWVELG GLRIEGDPEF WFSARRWTSE
QLDAARHLTD LTPGDTVWVS LDHGQHGIGS QSCGPGPLPR HFLRAEPTEF SFVFSTAR
//
