ID L8WR47_THACA Unreviewed; 1531 AA.
AC L8WR47;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=DNA-directed RNA polymerase subunit {ECO:0000256|RuleBase:RU004279};
DE EC=2.7.7.6 {ECO:0000256|RuleBase:RU004279};
GN ORFNames=AG1IA_06747 {ECO:0000313|EMBL:ELU39223.1};
OS Thanatephorus cucumeris (strain AG1-IA) (Rice sheath blight fungus)
OS (Rhizoctonia solani).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Cantharellales; Ceratobasidiaceae; Rhizoctonia; Rhizoctonia solani AG-1.
OX NCBI_TaxID=983506 {ECO:0000313|EMBL:ELU39223.1, ECO:0000313|Proteomes:UP000011668};
RN [1] {ECO:0000313|EMBL:ELU39223.1, ECO:0000313|Proteomes:UP000011668}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AG-1 IA {ECO:0000313|Proteomes:UP000011668};
RX PubMed=23361014; DOI=10.1038/ncomms2427;
RA Zheng A., Lin R., Xu L., Qin P., Tang C., Ai P., Zhang D., Liu Y., Sun Z.,
RA Feng H., Wang Y., Chen Y., Liang X., Fu R., Li Q., Zhang J., Yu X., Xie Z.,
RA Ding L., Guan P., Tang J., Liang Y., Wang S., Deng Q., Li S., Zhu J.,
RA Wang L., Liu H., Li P.;
RT "The evolution and pathogenic mechanisms of the rice sheath blight
RT pathogen.";
RL Nat. Commun. 4:1424-1424(2013).
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC {ECO:0000256|RuleBase:RU004279}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000256|ARBA:ARBA00024550,
CC ECO:0000256|RuleBase:RU004279};
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the RNA polymerase beta' chain family.
CC {ECO:0000256|ARBA:ARBA00006460, ECO:0000256|RuleBase:RU004279}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELU39223.1}.
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DR EMBL; AFRT01001873; ELU39223.1; -; Genomic_DNA.
DR STRING; 983506.L8WR47; -.
DR HOGENOM; CLU_000487_1_1_1; -.
DR OMA; MVQYDRT; -.
DR Proteomes; UP000011668; Unassembled WGS sequence.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006366; P:transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd02584; RNAP_II_Rpb1_C; 1.
DR CDD; cd02733; RNAP_II_RPB1_N; 1.
DR Gene3D; 1.10.132.30; -; 1.
DR Gene3D; 1.10.150.390; -; 1.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 3.30.1360.140; -; 1.
DR Gene3D; 6.10.250.2940; -; 1.
DR Gene3D; 6.20.50.80; -; 1.
DR Gene3D; 3.30.1490.180; RNA polymerase ii; 1.
DR Gene3D; 4.10.860.120; RNA polymerase II, clamp domain; 1.
DR Gene3D; 1.10.274.100; RNA polymerase Rpb1, domain 3; 1.
DR InterPro; IPR045867; DNA-dir_RpoC_beta_prime.
DR InterPro; IPR000722; RNA_pol_asu.
DR InterPro; IPR000684; RNA_pol_II_repeat_euk.
DR InterPro; IPR006592; RNA_pol_N.
DR InterPro; IPR007080; RNA_pol_Rpb1_1.
DR InterPro; IPR007066; RNA_pol_Rpb1_3.
DR InterPro; IPR042102; RNA_pol_Rpb1_3_sf.
DR InterPro; IPR007083; RNA_pol_Rpb1_4.
DR InterPro; IPR007081; RNA_pol_Rpb1_5.
DR InterPro; IPR007075; RNA_pol_Rpb1_6.
DR InterPro; IPR007073; RNA_pol_Rpb1_7.
DR InterPro; IPR038593; RNA_pol_Rpb1_7_sf.
DR InterPro; IPR044893; RNA_pol_Rpb1_clamp_domain.
DR InterPro; IPR038120; Rpb1_funnel_sf.
DR PANTHER; PTHR19376; DNA-DIRECTED RNA POLYMERASE; 1.
DR PANTHER; PTHR19376:SF37; DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1; 1.
DR Pfam; PF04997; RNA_pol_Rpb1_1; 1.
DR Pfam; PF00623; RNA_pol_Rpb1_2; 1.
DR Pfam; PF04983; RNA_pol_Rpb1_3; 1.
DR Pfam; PF05000; RNA_pol_Rpb1_4; 1.
DR Pfam; PF04998; RNA_pol_Rpb1_5; 1.
DR Pfam; PF04992; RNA_pol_Rpb1_6; 1.
DR Pfam; PF04990; RNA_pol_Rpb1_7; 1.
DR Pfam; PF05001; RNA_pol_Rpb1_R; 6.
DR SMART; SM00663; RPOLA_N; 1.
DR SUPFAM; SSF64484; beta and beta-prime subunits of DNA dependent RNA-polymerase; 1.
DR PROSITE; PS00115; RNA_POL_II_REPEAT; 2.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478,
KW ECO:0000256|RuleBase:RU004279};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695,
KW ECO:0000256|RuleBase:RU004279}; Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000011668};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU004279};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU004279};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 121..424
FT /note="RNA polymerase N-terminal"
FT /evidence="ECO:0000259|SMART:SM00663"
FT REGION 1478..1522
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1531 AA; 170833 MW; 584989528E841A23 CRC64;
MQNDTQFAEK IRHVRDPKKR MALVWAHCKG KMICEADETK DDEGAAAQPA KVGHGGCGHV
QPLIRKEGLK LFLVYKKGRD GRTSQPEKRL YPASDVYNTL KKIPDSDLAL LGLSEEFARP
DWMILTVLPV PPPPVRPSIS ADGGTVRSED DLTYKLGDIL KASINVRRCE EEGSPAHVIS
EFEQLLQFHV ATYMDNDIAG IPQALQKSGR PVKAIRARLK GKEGRLRGNL MGKRVDFSAR
TVITGDPNLM LDEVGVPRSM AMNLTYPERV TPYNIEWLQM LVRNGPREYP GARYVVRDSG
ERIDLRYNKR ADTSLQYGWI VERHLKNGDY VLFNRQPSLH KMSMMSHRVK IMPYSTFRLN
LSVTPPYNAD FDGDEMNMHI PQSEETRAEL SQIAWVPRQI ISPQANKPVM GIVQDTLCGI
RKITLRDNFL DWNFVQNILL WVPEWDGQVP VPTILKPKPL WTGKQILSLC IPSGINVFRA
PDKDKRTNRV PANPANDDGI CIENGEILYG VVEKKTVGAS QAGLIHITFR EKGPEITRDL
FTSLQKVVNF WLLHNGFSIG IGDTIADKDT MSKITIHIET AKNNVLQLIQ KAQYDGLRAE
PGMTIRESFE SHVNRELNMA RDKTGKDAQD SLKNDNNVKQ MVVAGSKGSF INISQMSGCV
GQQSVEGKRI PFGFKHRTLP HFNKDDYCAE SRGFVENSYL RGLTPQEFFF HAMAGREGLI
DTAVKTAETG YIQRRLVKAM EDIAVCYDGT VRNSLGDIVQ FAYGEDGMDG AFIERQSVEP
YRLSNRAFER KYRVDVLEAG SGFSPGTLQV GLDASSPELQ YKLDNEYAQL VKDRKMLREF
IFKTADPNQP HYLPVNLRRV IQNAQQIFHI DRRKPSDLEP AYIMDEVAGL SSRLIVVRGE
DPISLEAQDN ATMLFNMHLR STFATRPVLE ELRLTKQAFD WIIGEVETKF NASIVNPGEM
CGTLAAQSIG EPATQMTLNT FHYAGVSSKN VTLGVPRLKE IINVATNIKT PSLTVYLQSE
YASSKHKAKT IQTELAHTTL RTITATTEIV YDPDPTNTII DEDRDFVETF FAIPDESVER
TLSQQSPWVL RIQLDRAKVL DKKLDMAYIA DRIEQAFYPD MKVIPSDDNA EKLILRCRPI
VMQDKDEEAF ENTEEDIFIR QIEHNMLDSV TLRGVKGIRR VFMVEHDKPM IDAAGELQPR
SAKEWVLETD GVNLKSVLSV DGIDFTRTYS NKCPEVFEVL GIEAARAAIL RELRNVIEFD
GSYVNYRHLA LLTDLMTNRG TLMAITRHGI NRADTGALMR CSFEETVEIL MEAAAVGEKD
DCYGVAENVL FGQMAPMGTG SFDVALDVDM LKDVIVDSRL PIQNMMAAQM GGGATPAGGL
AMTPYDSASP MQAEAWRTEG AAFSPLATNA DEASGGFSFI PFGQSPMGPD SRFGGYSPSS
PGYSPTSPFM PTSPMVAATS PYGASPFGAT SPYATSPAYS PTSPNMNLTS PQYSPTSPQY
SPTSPTYSPT SPTYSPTSPR YYSTCEYLAR G
//
