ID L8WU07_THACA Unreviewed; 1127 AA.
AC L8WU07;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=116 kDa U5 small nuclear ribonucleoprotein component {ECO:0000256|ARBA:ARBA00018774};
DE AltName: Full=U5 snRNP-specific protein, 116 kDa {ECO:0000256|ARBA:ARBA00031432};
GN ORFNames=AG1IA_05723 {ECO:0000313|EMBL:ELU40248.1};
OS Thanatephorus cucumeris (strain AG1-IA) (Rice sheath blight fungus)
OS (Rhizoctonia solani).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Cantharellales; Ceratobasidiaceae; Rhizoctonia; Rhizoctonia solani AG-1.
OX NCBI_TaxID=983506 {ECO:0000313|EMBL:ELU40248.1, ECO:0000313|Proteomes:UP000011668};
RN [1] {ECO:0000313|EMBL:ELU40248.1, ECO:0000313|Proteomes:UP000011668}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AG-1 IA {ECO:0000313|Proteomes:UP000011668};
RX PubMed=23361014; DOI=10.1038/ncomms2427;
RA Zheng A., Lin R., Xu L., Qin P., Tang C., Ai P., Zhang D., Liu Y., Sun Z.,
RA Feng H., Wang Y., Chen Y., Liang X., Fu R., Li Q., Zhang J., Yu X., Xie Z.,
RA Ding L., Guan P., Tang J., Liang Y., Wang S., Deng Q., Li S., Zhu J.,
RA Wang L., Liu H., Li P.;
RT "The evolution and pathogenic mechanisms of the rice sheath blight
RT pathogen.";
RL Nat. Commun. 4:1424-1424(2013).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELU40248.1}.
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DR EMBL; AFRT01001476; ELU40248.1; -; Genomic_DNA.
DR AlphaFoldDB; L8WU07; -.
DR STRING; 983506.L8WU07; -.
DR HOGENOM; CLU_002794_11_2_1; -.
DR OMA; YIFRPIR; -.
DR Proteomes; UP000011668; Unassembled WGS sequence.
DR GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR CDD; cd04098; eEF2_C_snRNP; 1.
DR CDD; cd01683; EF2_IV_snRNP; 1.
DR CDD; cd16264; snRNP_III; 1.
DR CDD; cd04167; Snu114p; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.70.240; -; 1.
DR Gene3D; 3.30.70.870; Elongation Factor G (Translational Gtpase), domain 3; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR InterPro; IPR041095; EFG_II.
DR InterPro; IPR035647; EFG_III/V.
DR InterPro; IPR000640; EFG_V-like.
DR InterPro; IPR031950; EFTUD2_N.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR044121; Snu114_GTP-bd.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR005517; Transl_elong_EFG/EF2_IV.
DR InterPro; IPR035655; U5-116kDa_C.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR42908:SF6; 116 KDA U5 SMALL NUCLEAR RIBONUCLEOPROTEIN COMPONENT; 1.
DR PANTHER; PTHR42908; TRANSLATION ELONGATION FACTOR-RELATED; 1.
DR Pfam; PF00679; EFG_C; 1.
DR Pfam; PF14492; EFG_III; 1.
DR Pfam; PF03764; EFG_IV; 1.
DR Pfam; PF16004; EFTUD2; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SMART; SM00838; EFG_C; 1.
DR SMART; SM00889; EFG_IV; 1.
DR SUPFAM; SSF54980; EF-G C-terminal domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000011668};
KW Spliceosome {ECO:0000256|ARBA:ARBA00022728}.
FT DOMAIN 266..476
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT REGION 43..67
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 145..182
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 51..66
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1127 AA; 125713 MW; 312D2C482556DF62 CRC64;
MWESSGLEVS CRSKGIERVE VERGWCCRGT GATVVGWARP RKESSEMKCK SSRGTHASQT
NTGRDRPQIR PWAILRTQGI TYGIVETEDM YGLPALHKLH NSSLCVDESD KRVAITSAGK
HWDADDHGQL GRLRRAQFGN YIGADLDSDD EEELDAPQSY AQPTHDEPSH APLEGFDDEP
SNALMELDDA PKHNAVILHE DKKYYPSAEE VYGPDVETLV QEEDAQPLSE PIIAPVKVRN
WVIEEKGLPE TRFDKRFLLD LMSFPEMIRN VAVVGHLHHG KTSLIDMLVF ETHKMVWDSD
KQLRYTDTHP LSAQRLISLK ANSMSLVLSN SRGKSHLVHL LDTPGHMNFV DETASAMRLV
DGIVLVVDIV EGVMVGTEAI IRHALAENLP IVLVLNKIDR LILELRLPPA DAYFKIKHTI
EEVNTFLAGI NPDPALRLSP ERGNVAFAST EMGWCFTLRS FAQMYAAEWE GVDVQEFSRR
LWGDIYFDES SRKFGRKAGG EAKRSFVHFI LEPVLSADRE DLKSTLAGLG ITLKPILYKM
DSRPLLKAVL DQFFGPAVGL VDMLVEWIPS AAEGTAAKVE RTYTGPLNTP TAQAMLACNN
TAKAPTIVQI TKLLPAKDAQ SFRALGRVMS GVVKRGMPVR VLGEGFSADD EEDMWKGDLG
DVWITEARYA SLRRIIVLLG GIDSSITKTA TLVAPPSEES EHDYESDDVF IFRPIKHITQ
SVLKVAVEPI SPSELPKMLS GLRSVNKSYP LLHTKVEESG EHVIVGTGEL YLDCVLHDLR
RVFAEIEIKV SDPVTRFCET VVETSALKCY AETPNKKNKI TMIAEPLERG LAEDIEGGKI
TMRMAPKDRG KILQERYQWD LLASRAVWAF GPEEQGPNVL LDDTLPSQVD KKMLGTVKEH
IKQGFQWGAR EGPLCDEPIR NVKFRILDAT LAQEPIFRGG GQIVPTATPR LMEPIFYVEV
QAPADCISAV YTVLARRRGH VTQDIPKAGS PLYTIKALIP AIDANGFETD LRTATQGQAF
CIQMFDHWSI VPGDPTDSSI KLRPLEPATG QALARDLVLK TRRRKGLGDQ IAVSKYLDDE
FVVSRFSDFG LESRADRGVA FFRSLHCRHL DMRIFWDKIL GSPTSRY
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