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Database: UniProt
Entry: L8Y4G7_TUPCH
LinkDB: L8Y4G7_TUPCH
Original site: L8Y4G7_TUPCH 
ID   L8Y4G7_TUPCH            Unreviewed;      1125 AA.
AC   L8Y4G7;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   27-SEP-2017, entry version 29.
DE   SubName: Full=Potassium voltage-gated channel subfamily KQT member 2 {ECO:0000313|EMBL:ELV11338.1};
GN   ORFNames=TREES_T100018228 {ECO:0000313|EMBL:ELV11338.1};
OS   Tupaia chinensis (Chinese tree shrew).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Scandentia; Tupaiidae; Tupaia.
OX   NCBI_TaxID=246437 {ECO:0000313|EMBL:ELV11338.1, ECO:0000313|Proteomes:UP000011518};
RN   [1] {ECO:0000313|Proteomes:UP000011518}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Zhang G., Fan Y., Yao Y., Huang Z.;
RT   "Genome of the Chinese tree shrew, a rising model animal genetically
RT   related to primates.";
RL   Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the potassium channel family.
CC       {ECO:0000256|SAAS:SAAS00692852}.
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DR   EMBL; KB365278; ELV11338.1; -; Genomic_DNA.
DR   ProteinModelPortal; L8Y4G7; -.
DR   InParanoid; L8Y4G7; -.
DR   Proteomes; UP000011518; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0008076; C:voltage-gated potassium channel complex; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0003746; F:translation elongation factor activity; IEA:InterPro.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR   InterPro; IPR020969; Ankyrin-G_BS.
DR   InterPro; IPR004161; EFTu-like_2.
DR   InterPro; IPR031157; G_TR_CS.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR003937; K_chnl_volt-dep_KCNQ.
DR   InterPro; IPR003947; K_chnl_volt-dep_KCNQ2.
DR   InterPro; IPR013821; K_chnl_volt-dep_KCNQ_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR000795; TF_GTP-bd_dom.
DR   InterPro; IPR009000; Transl_B-barrel.
DR   InterPro; IPR004539; Transl_elong_EF1A_euk/arc.
DR   InterPro; IPR004160; Transl_elong_EFTu/EF1A_C.
DR   InterPro; IPR028325; VG_K_chnl.
DR   PANTHER; PTHR11537; PTHR11537; 1.
DR   Pfam; PF00009; GTP_EFTU; 1.
DR   Pfam; PF03144; GTP_EFTU_D2; 1.
DR   Pfam; PF03143; GTP_EFTU_D3; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF03520; KCNQ_channel; 1.
DR   Pfam; PF11956; KCNQC3-Ank-G_bd; 1.
DR   PRINTS; PR00169; KCHANNEL.
DR   PRINTS; PR01461; KCNQ2CHANNEL.
DR   PRINTS; PR01459; KCNQCHANNEL.
DR   SUPFAM; SSF50447; SSF50447; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00483; EF-1_alpha; 1.
DR   PROSITE; PS00301; G_TR_1; 1.
DR   PROSITE; PS51722; G_TR_2; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000011518};
KW   Ion channel {ECO:0000256|SAAS:SAAS00417203};
KW   Ion transport {ECO:0000256|SAAS:SAAS00417186};
KW   Membrane {ECO:0000256|SAAS:SAAS00788393, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|SAAS:SAAS00417282};
KW   Potassium channel {ECO:0000256|SAAS:SAAS00417246};
KW   Potassium transport {ECO:0000256|SAAS:SAAS00417240};
KW   Reference proteome {ECO:0000313|Proteomes:UP000011518};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00793138,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00789957,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00417268}.
FT   TRANSMEM    437    456       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    468    491       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    512    531       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    578    596       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    637    662       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN        5    242       Tr-type G. {ECO:0000259|PROSITE:PS51722}.
SQ   SEQUENCE   1125 AA;  124433 MW;  BBE363D74E91903A CRC64;
     MGKEKTHINI VVIGHVDSGK STTTGHLIYK CGGIDKRTIE KFEKEAAEMG KGSFKYAWVL
     DKLKAERERG ITIDISLWKF ETTKYYITII DAPGHRDFIK NMITGTSQAD CAVLIVAAGV
     GEFEAGISKN GQTREHALLA YTLGVKQLIV GVNKMDSTEP AYSEKRYDEI VKEVSAYIKK
     IGYNPATVPF VPISGWHGDN MLEPSPNMPW FKGWKVERKE GNASGVSLLE ALDTILPPTR
     PTDKPLRLPL QDVYKIGGIG TVPVGRVETG ILRPGMVVTF APVNITTEVK SVEMHHEALS
     EALPGDNVGF NVKNVSVKDI RRGNVCGDSK SDPPQEAAQF TSQVIILNHP GQISAGYSPV
     IDCHTAHIAC KFAELKEKID RRSGKKLEDN PKSLKSGDAA IVEMVPGKPM PPKRNAFYRK
     LQNFLYNVLE RPRGWAFIYH AYVFLLVFSC LVLSVFSTIK EYEKSSEGAL YILEIVTIVV
     FGVEYFVRIW AAGCCCRYRG WRGRLKFARK PFCVIDIMVL VASIAVLAAG SQGNVFATSA
     LRSLRFLQIL RMIRMDRRGG TWKLLGSVVY AHSKELVTAW YIGFLCLILA SFLVYLAEKG
     ENDHFDTYAD ALWWGLITLT TIGYGDKYPQ TWNGRLLAAT FTLIGVSFFA LPAGILGSGF
     ALKVQEQHRQ KHFEKRRNPA AGLIQSAWRF YATNLSRTDL HSTWHYYERT VTVPMYRLIP
     PLNQLELLRN LKSKSGLTFS PRAVTAKGKG SPQAQTVRRS PSADQSLEDS PSKVPKSWSF
     GDRSRARQAF RIKGAASRQN SEEASLPGED AVDDKSCNCE FVTEDLTPGL KVSIRAVCVM
     RFLVSKRKFK ESLRPYDVMD VIEQYSAGHL DMLSRIKSLQ ARQGPPARWT RVDQIVGRGP
     AIADKDRTKG PTDAELPEDP SMMGRLGKVE KQVLSMEKKL DFLVSIYTQR MGIPPAEAEA
     YFGAKEPEPC PPSTSWQRQG HGVSPAGDHS SLVRIPPPPT HERSLSAYSG GNRASTEFLR
     LEDAPGGRPH EGALRDSDTS ISIPSVDHEE LERSFSGFSI SQSKENLDAL NSCYAAAAPC
     AKVRPYIAEG ESDTDSDLCT PCGPPPRSAT GEGPFGDVGW AGPRK
//
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