ID L8YD25_TUPCH Unreviewed; 718 AA.
AC L8YD25;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Transcription termination factor 2 {ECO:0000313|EMBL:ELV14147.1};
GN ORFNames=TREES_T100003485 {ECO:0000313|EMBL:ELV14147.1};
OS Tupaia chinensis (Chinese tree shrew).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Scandentia; Tupaiidae; Tupaia.
OX NCBI_TaxID=246437 {ECO:0000313|EMBL:ELV14147.1, ECO:0000313|Proteomes:UP000011518};
RN [1] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Zhang G., Fan Y., Yao Y., Huang Z.;
RT "Genome of the Chinese tree shrew, a rising model animal genetically
RT related to primates.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23385571; DOI=10.1038/ncomms2416;
RA Fan Y., Huang Z.Y., Cao C.C., Chen C.S., Chen Y.X., Fan D.D., He J.,
RA Hou H.L., Hu L., Hu X.T., Jiang X.T., Lai R., Lang Y.S., Liang B.,
RA Liao S.G., Mu D., Ma Y.Y., Niu Y.Y., Sun X.Q., Xia J.Q., Xiao J.,
RA Xiong Z.Q., Xu L., Yang L., Zhang Y., Zhao W., Zhao X.D., Zheng Y.T.,
RA Zhou J.M., Zhu Y.B., Zhang G.J., Wang J., Yao Y.G.;
RT "Genome of the Chinese tree shrew.";
RL Nat. Commun. 4:1426-1426(2013).
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DR EMBL; KB359359; ELV14147.1; -; Genomic_DNA.
DR AlphaFoldDB; L8YD25; -.
DR STRING; 246437.L8YD25; -.
DR eggNOG; KOG4439; Eukaryota.
DR InParanoid; L8YD25; -.
DR Proteomes; UP000011518; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProt.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd18793; SF2_C_SNF; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR049730; SNF2/RAD54-like_C.
DR InterPro; IPR000330; SNF2_N.
DR PANTHER; PTHR45626:SF54; TRANSCRIPTION TERMINATION FACTOR 2; 1.
DR PANTHER; PTHR45626; TRANSCRIPTION TERMINATION FACTOR 2-RELATED; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000011518}.
FT DOMAIN 551..713
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..168
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 199..221
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 238..263
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..28
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 42..117
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 118..134
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 135..157
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 718 AA; 80096 MW; A21D96A022C8FBCE CRC64;
MSDKKPREKG DQLFDQKKVQ KPESNRGLDK EPSSGLVIKK NQHVVQEKKQ VRRTELQCEA
KEPGDTHKRN FSEIKPTQHH DNELRRPPAS HQERSNQKIQ DARKESEPLR EKETQLLPRN
VHSQNSVSKP QNRGQHSREP LKNQEAKEPK AKGDPKPQSI PKRLPQGHFK VSLETCDVSV
PVGPVAQAAP AAPVLSLGEG SEATVISDDS EEDDDVASSK SSSPLLFDLT VDSQKNLQFP
DQSVQRQISP APSISKRTEP SDPAAQRAFL TTQLKQKKVP LLLHQKQALA WLLWRESQKP
QGGILDSSDF TSHGTLIICP ASLIHHWKNE VEKHVNSNKL RVYLYHGPNR NQSAKVLSTY
DVVITTYTLL AKEIPTQKEE GETPGPKLRV EGISTPLLRV VWARIILDEA HNVKNPRVQT
SIAVVLPQRK FQLHHLKLSE DEETVYSVFF ARSRSALQSY LKRHENGGNQ SGKDPDNPFS
RAARTDLDSA QALDPTELKS EGLVLSLEEQ LGALTLSELH DPGPSSTVSL NGTSFKVELF
EDTRKSTKIS SLLAELEAIR RNSRSQKSVI VSQWTSMLKV VALHLKRHGL TYATIDGSVN
PKQRMDLVEA FNHSGGPQVM LISLLAGGVG LNLTGGNHLF LLDMHWNPSL EDQACDRIYR
VGQQKDVVIH RFVCEGTVEE KILQLQEKKK DLAKQVLSGS GESVTKLTLA DLKVLFGI
//
