ID L9JRR9_TUPCH Unreviewed; 1829 AA.
AC L9JRR9;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Down syndrome cell adhesion molecule like protein {ECO:0000313|EMBL:ELW53216.1};
DE Flags: Fragment;
GN ORFNames=TREES_T100017912 {ECO:0000313|EMBL:ELW53216.1};
OS Tupaia chinensis (Chinese tree shrew).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Scandentia; Tupaiidae; Tupaia.
OX NCBI_TaxID=246437 {ECO:0000313|EMBL:ELW53216.1, ECO:0000313|Proteomes:UP000011518};
RN [1] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Zhang G., Fan Y., Yao Y., Huang Z.;
RT "Genome of the Chinese tree shrew, a rising model animal genetically
RT related to primates.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23385571; DOI=10.1038/ncomms2416;
RA Fan Y., Huang Z.Y., Cao C.C., Chen C.S., Chen Y.X., Fan D.D., He J.,
RA Hou H.L., Hu L., Hu X.T., Jiang X.T., Lai R., Lang Y.S., Liang B.,
RA Liao S.G., Mu D., Ma Y.Y., Niu Y.Y., Sun X.Q., Xia J.Q., Xiao J.,
RA Xiong Z.Q., Xu L., Yang L., Zhang Y., Zhao W., Zhao X.D., Zheng Y.T.,
RA Zhou J.M., Zhu Y.B., Zhang G.J., Wang J., Yao Y.G.;
RT "Genome of the Chinese tree shrew.";
RL Nat. Commun. 4:1426-1426(2013).
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DR EMBL; KB320951; ELW53216.1; -; Genomic_DNA.
DR STRING; 246437.L9JRR9; -.
DR eggNOG; KOG3510; Eukaryota.
DR InParanoid; L9JRR9; -.
DR Proteomes; UP000011518; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR CDD; cd00063; FN3; 6.
DR CDD; cd00096; Ig; 2.
DR CDD; cd05734; Ig_DSCAM; 1.
DR CDD; cd05735; Ig_DSCAM; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 15.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR10075; BASIGIN RELATED; 1.
DR Pfam; PF00041; fn3; 5.
DR Pfam; PF07679; I-set; 4.
DR Pfam; PF13927; Ig_3; 2.
DR SMART; SM00060; FN3; 6.
DR SMART; SM00409; IG; 7.
DR SMART; SM00408; IGc2; 7.
DR SUPFAM; SSF49265; Fibronectin type III; 4.
DR SUPFAM; SSF48726; Immunoglobulin; 6.
DR PROSITE; PS50853; FN3; 6.
DR PROSITE; PS50835; IG_LIKE; 7.
PE 4: Predicted;
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Neurogenesis {ECO:0000256|ARBA:ARBA00022902};
KW Reference proteome {ECO:0000313|Proteomes:UP000011518};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1412..1433
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 58..138
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 146..234
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 240..333
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 337..426
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 431..576
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 580..676
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 678..775
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 835..936
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 941..1037
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1041..1135
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1135..1227
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1195..1290
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1291..1392
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 1535..1627
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1672..1700
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1760..1829
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1542..1627
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1672..1686
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1764..1785
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1799..1813
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ELW53216.1"
SQ SEQUENCE 1829 AA; 202008 MW; 697D7517B45CAF61 CRC64;
VSGSRFLITS TGALYIKDVQ NEDGLYNYRC VTRHRYTGET RQSNSARLFV SDPANSAPSI
LDGFDHRKAM AGQRVELPCK ALGHPEPDYR WLKDNMPLEL SGRFQKTVTG LLIENTRPSD
SGSYVCEVSN RYGTAKVIGR LYVKQPLKAT ISPRKVKSSV GSQVSLSCSV TGTEDQELSW
YRNGEILNPG KNVRITGINH ENLIMDHMVK SDGGAYQCFV RKDKLSAQDY VQVVLEDGTP
KIISAFSEKV VSPAEPVSLM CNVKGTPLPT ITWTLDDDPI LKGGSHRISQ MITSEGNVVS
YLNISSSQVR DGGVYRCTAN NSAGVVLYQA RINVRVPPFI QPFEFPRFSI GQRVFIPCVV
VSGDLPITIT WQKDGRPIPA SLGVTIDNID FTSSLRISNL SLMHNGNYTC IARNEAAAVE
HQSQLIVRVP PKFVVQPRDQ DGIYGKAVIL NCSAEGYPVP TIVWKFSKGP QKQPLLTVNL
PVEIFCSNHK SSHQGLDSSV DEFMEIQLDS HINYLDVSMK GAGVPQFQPI ALNGRIQVLS
NGSLLIKHVV EEASGYYLCK VSNDVGADVS KSMYLTVKIP AMITSYPNTT LATQGQKKEM
SCTAHGEKPI IVRWEKEDRI INPEMARYLV STKEVGEEVI STLQILPTVR EDSGFFSCHA
INSYGEDRGI IQLTVQEPPD PPEIEIKDVK ARTITLRWTM GFDGNSPITG YDIECKNKSD
SWDSAQRTKD VSPQLNSATI IDIHPSSTYS IRMYAKNRIG KSEPSNELTI TADEAAPDGP
PQEVHLEPIS SQSIRVTWKA PKKHLQNGII RGYQIGYREY STGGNFQFNI ISIDTTGDSE
VYTLDNLNKF TQYGLVAPKK HLQNGIIRGY QIGYREYSTG GNFQFNIISI DTTGDSEVYT
LDNLNKFTQY GLVVQACNRA GTGPSSQEII TTTLEDVPSY PPENVQAIAT SPESISISWS
TLSKEALNGI LQGFRVIYWA NLMDGELGEI KNVTTTQPSL ELDGLEKYTN YSIQVLAFTR
AGDGVRSEQI FTRTKEDVPG PPAGVKAAAA SASMVFVSWL PPLKLNGIIR KYTVFCSHPY
PTVISEFEAS PDSFSYRIPN LSRNRQYSVW VVAVTSAGRG NSSEIITVEP LAKAPARILT
FSGTVTTPWM KDIVLPCKAV GDPSPAVKWM KDSNGTPSLV TIDGRRGIFS NGSFIIRTVK
AEDSGYYSCI ANNNWGSDEI ILNLQVQGYI LQYSEDNSEQ WGSFPISPSE RSYRLENLKC
GTWYKFTLTA QNGVGPGRIS EIIEAKTLGK EPQFSKEQEL FASINTTRVR LNLVGWNDGG
CPITSFTLEY RPFGTTVWTT AQRTSLSKSY ILYDLQEATW YELQMRVCNS AGCAEKQANF
ATLNYDGSTI PPLIKSVVQS EEGLTTNEGL KMLVTISCIL VGVLLLFALL LVVRRRRREQ
RLKRLRDAKS LAEMLMSKNT RTSDTLSKQQ QTLRMHIDIP RAQLLIEERD TMETIDDRST
VLLTDADFGE AAKQKSLTVT HTVHYQSVSQ ATGPLVDVSD ARPGTNPTTR RNAKAGPTAR
NRYASQWTLN RPHPTISAHT LTTDWRLPTP RATGSVDKES DSYSVSPSQD TDRARSSMVS
TESASSTYEE LARAYEHAKM EEQLRHAKFT ITECFISDTS SEQLTAGTNE YTDSLTSSTP
SESGICRFTA SPPKPQDGGR VMNMAVPKAH RPGDLIHLPP YLRMDFLLNR GGPGTSRDLS
LGQACLEPQK SRTLKRPTVL EPIPMEASSS TSSTREGQSW QAGAVATLPQ REGAELGQAA
KMSSSQESLL DSRGHLKGNN PYAKSYTLV
//
