ID L9JWR9_TUPCH Unreviewed; 916 AA.
AC L9JWR9;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE SubName: Full=Keratin, type I cuticular Ha3-I {ECO:0000313|EMBL:ELW54936.1};
GN ORFNames=TREES_T100004417 {ECO:0000313|EMBL:ELW54936.1};
OS Tupaia chinensis (Chinese tree shrew).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Scandentia; Tupaiidae; Tupaia.
OX NCBI_TaxID=246437 {ECO:0000313|EMBL:ELW54936.1, ECO:0000313|Proteomes:UP000011518};
RN [1] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Zhang G., Fan Y., Yao Y., Huang Z.;
RT "Genome of the Chinese tree shrew, a rising model animal genetically
RT related to primates.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23385571; DOI=10.1038/ncomms2416;
RA Fan Y., Huang Z.Y., Cao C.C., Chen C.S., Chen Y.X., Fan D.D., He J.,
RA Hou H.L., Hu L., Hu X.T., Jiang X.T., Lai R., Lang Y.S., Liang B.,
RA Liao S.G., Mu D., Ma Y.Y., Niu Y.Y., Sun X.Q., Xia J.Q., Xiao J.,
RA Xiong Z.Q., Xu L., Yang L., Zhang Y., Zhao W., Zhao X.D., Zheng Y.T.,
RA Zhou J.M., Zhu Y.B., Zhang G.J., Wang J., Yao Y.G.;
RT "Genome of the Chinese tree shrew.";
RL Nat. Commun. 4:1426-1426(2013).
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|RuleBase:RU000685}.
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DR EMBL; KB320933; ELW54936.1; -; Genomic_DNA.
DR AlphaFoldDB; L9JWR9; -.
DR STRING; 246437.L9JWR9; -.
DR eggNOG; ENOG502SNBF; Eukaryota.
DR InParanoid; L9JWR9; -.
DR Proteomes; UP000011518; Unassembled WGS sequence.
DR GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR Gene3D; 1.20.5.170; -; 2.
DR Gene3D; 1.20.5.500; Single helix bin; 2.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 3.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR002957; Keratin_I.
DR PANTHER; PTHR23239; INTERMEDIATE FILAMENT; 1.
DR PANTHER; PTHR23239:SF97; KERATIN, TYPE I CUTICULAR HA1; 1.
DR Pfam; PF00038; Filament; 3.
DR PRINTS; PR01248; TYPE1KERATIN.
DR SMART; SM01391; Filament; 2.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 5.
DR PROSITE; PS00226; IF_ROD_1; 2.
DR PROSITE; PS51842; IF_ROD_2; 3.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|RuleBase:RU000685};
KW Reference proteome {ECO:0000313|Proteomes:UP000011518}.
FT DOMAIN 56..142
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT DOMAIN 201..512
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT DOMAIN 568..879
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT COILED 60..130
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 205..275
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 304..349
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 396..497
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 572..642
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 671..716
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 777..864
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 916 AA; 104585 MW; E398F4736834C107 CRC64;
MSCNCCLSNL SCRTSCCSRP CVPPSCHSCT LPGACNIPAN VSNCNWFCEG SFNGSEKETM
QFLNDRLASY LEKVRQLERD NAELESRIRE RCQPQQPIVC ASYQSYFRTI EELQQKILCA
KSENARLVAQ IDNAKLAADD FRTNIMSCNC CLSNLSCRTS CCSRPCVPPS CHSCTLPGAC
NIPANVSNCN WFCEGSFNGS EKETMQFLND RLASYLEKVR QLERDNAELE SRIRERCQPQ
DPIVCASYQS YFRTIEELQQ KILCAKSENA RLVAQIDNAK LAADDFRTKY ETERSLRQLV
ESDINSLRRI LDELTLCKSD LEAQVESLRE ELLCLKKNHE EEVNILRCQI GDRLNVEVDA
APAVDLNRVL NETRCQYEAL VDTNRREVEE WYTTQSEELN KQVVSSSEQL QTCQAEIIEL
RRTVNALEIE LQAQHNLRDS LENTLTESEA RYSSQLSQIQ CMITNVESQL AEIRCDLERQ
NQEYQVLLDV RARLECEINT YRGLLEGEDC NTMPYNCCLP NLSCRTSCCS RPCVPPSCHS
CTLPGACNIP ANVSNCNWFC EGTFNGSEKE TMQFLNDRLA SYLEKVRQLE RDNAELECRI
RERCQPQDPI VCASYQSYFR TIEELQQKIL CAKSENARLV VQIDNAKLAA DDFRTKYQTE
LSLRQLVEAD INSLRRILDE LTLCKSDLEA QVESLKEELL CLKQNHEQEV NTLRCQIGDR
LNVEVDAAPT VDLNRVLNET RCQYEALVDT NRREVEEWFT TQTEELNKQV VSSSEQLQTC
QAEIIELRRT VNALEIELQA QHNLRDSLEN TLTESEARYS SQLSQVQCMI TNVESQLAEI
RCDLERQNQE YQVLLDVRAR LECEINTYRG LLESEDCNLP CNPCATTNAC DKPIGPCVTN
PCCSRPRCGP CNNFGC
//
