ID L9KK29_TUPCH Unreviewed; 631 AA.
AC L9KK29;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=PUM-HD domain-containing protein {ECO:0000259|PROSITE:PS50303};
GN ORFNames=TREES_T100010023 {ECO:0000313|EMBL:ELW63088.1};
OS Tupaia chinensis (Chinese tree shrew).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Scandentia; Tupaiidae; Tupaia.
OX NCBI_TaxID=246437 {ECO:0000313|EMBL:ELW63088.1, ECO:0000313|Proteomes:UP000011518};
RN [1] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Zhang G., Fan Y., Yao Y., Huang Z.;
RT "Genome of the Chinese tree shrew, a rising model animal genetically
RT related to primates.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23385571; DOI=10.1038/ncomms2416;
RA Fan Y., Huang Z.Y., Cao C.C., Chen C.S., Chen Y.X., Fan D.D., He J.,
RA Hou H.L., Hu L., Hu X.T., Jiang X.T., Lai R., Lang Y.S., Liang B.,
RA Liao S.G., Mu D., Ma Y.Y., Niu Y.Y., Sun X.Q., Xia J.Q., Xiao J.,
RA Xiong Z.Q., Xu L., Yang L., Zhang Y., Zhao W., Zhao X.D., Zheng Y.T.,
RA Zhou J.M., Zhu Y.B., Zhang G.J., Wang J., Yao Y.G.;
RT "Genome of the Chinese tree shrew.";
RL Nat. Commun. 4:1426-1426(2013).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KB320796; ELW63088.1; -; Genomic_DNA.
DR AlphaFoldDB; L9KK29; -.
DR STRING; 246437.L9KK29; -.
DR eggNOG; KOG1500; Eukaryota.
DR eggNOG; KOG2050; Eukaryota.
DR InParanoid; L9KK29; -.
DR Proteomes; UP000011518; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR012959; CPL_dom.
DR InterPro; IPR033133; PUM-HD.
DR InterPro; IPR040059; PUM3.
DR InterPro; IPR001313; Pumilio_RNA-bd_rpt.
DR PANTHER; PTHR13389:SF0; PUMILIO HOMOLOG 3; 1.
DR PANTHER; PTHR13389; UNCHARACTERIZED; 1.
DR Pfam; PF08144; CPL; 1.
DR SMART; SM00025; Pumilio; 5.
DR SUPFAM; SSF48371; ARM repeat; 2.
DR PROSITE; PS50302; PUM; 2.
DR PROSITE; PS50303; PUM_HD; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000011518};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT DOMAIN 135..516
FT /note="PUM-HD"
FT /evidence="ECO:0000259|PROSITE:PS50303"
FT REPEAT 200..235
FT /note="Pumilio"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00317"
FT REPEAT 407..443
FT /note="Pumilio"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00317"
FT REGION 1..121
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..48
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 67..121
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 631 AA; 71628 MW; FA037459CEF9BA74 CRC64;
MEVKAKKQLT GRNTKASQEK KRFRKNRDSG SLKTFPRKVV KEGGPKIASK NFEKSATKPG
KKGVKQVKNK QQGDKAPKNK FQQADKFNKK RKFQSDSQSD DSAAKKPKWD DFKKKKKELK
QSRQLNDKTN YDIVARSKQI WEILRRKDCD KEKRVKLMND LQKLIQGKIK TIAFAHDSTR
VIQCYIQYGN EEQRKQAFEE LRGDLVELSK AKYSRNIVKK FLMYGSKPQI AEIIRSFKGH
VRKMLRHAEA SAIVEYAYND KAILEQRNML TEELYGNTFQ LYKARSADHP TLDKVLEAKP
EKLELIMDEM KQILTPMAQK EAVIKHSLVH KVFLDFFTYA PPKLRSELIE AIREAVIYLA
HTHDGARVAM HCLWHGTPKG QYSHLVLLAA FDCIDDTKLV KQIIISEIIS SLPNIVADKY
GRKVLLYLLS PRDPAHTVRE IIEVLQKGDG NAHSKKDTEI RRRELLESIS PALLSYLQGH
AQDMVLDKSA CVLVADILGS ATGNVQPAMD AIASLAAAEL HPGGRDGELH VAEHPAGHLV
LKWLIEQDKK MKENGREDCF AKTLVEHVGM KNLKSWTNIN RGAIILSSLL QSPDQEVANK
VKAGLKSLIP TLERNKNPSK GIEILLEKLT A
//
