ID L9KVW2_TUPCH Unreviewed; 366 AA.
AC L9KVW2;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 24-JAN-2024, entry version 44.
DE RecName: Full=Olfactory receptor {ECO:0000256|RuleBase:RU363047};
GN ORFNames=TREES_T100007550 {ECO:0000313|EMBL:ELW66838.1};
OS Tupaia chinensis (Chinese tree shrew).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Scandentia; Tupaiidae; Tupaia.
OX NCBI_TaxID=246437 {ECO:0000313|EMBL:ELW66838.1, ECO:0000313|Proteomes:UP000011518};
RN [1] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Zhang G., Fan Y., Yao Y., Huang Z.;
RT "Genome of the Chinese tree shrew, a rising model animal genetically
RT related to primates.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23385571; DOI=10.1038/ncomms2416;
RA Fan Y., Huang Z.Y., Cao C.C., Chen C.S., Chen Y.X., Fan D.D., He J.,
RA Hou H.L., Hu L., Hu X.T., Jiang X.T., Lai R., Lang Y.S., Liang B.,
RA Liao S.G., Mu D., Ma Y.Y., Niu Y.Y., Sun X.Q., Xia J.Q., Xiao J.,
RA Xiong Z.Q., Xu L., Yang L., Zhang Y., Zhao W., Zhao X.D., Zheng Y.T.,
RA Zhou J.M., Zhu Y.B., Zhang G.J., Wang J., Yao Y.G.;
RT "Genome of the Chinese tree shrew.";
RL Nat. Commun. 4:1426-1426(2013).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651,
CC ECO:0000256|RuleBase:RU363047}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU363047}.
CC Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000256|RuleBase:RU000688}.
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DR EMBL; KB320636; ELW66838.1; -; Genomic_DNA.
DR AlphaFoldDB; L9KVW2; -.
DR STRING; 246437.L9KVW2; -.
DR eggNOG; ENOG502T9MH; Eukaryota.
DR InParanoid; L9KVW2; -.
DR Proteomes; UP000011518; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
DR CDD; cd15421; 7tmA_OR2T-like; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR000725; Olfact_rcpt.
DR PANTHER; PTHR26453; OLFACTORY RECEPTOR; 1.
DR PANTHER; PTHR26453:SF150; OLFACTORY RECEPTOR; 1.
DR Pfam; PF13853; 7tm_4; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR00245; OLFACTORYR.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|RuleBase:RU363047};
KW G-protein coupled receptor {ECO:0000256|RuleBase:RU000688};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363047};
KW Olfaction {ECO:0000256|ARBA:ARBA00022725, ECO:0000256|RuleBase:RU363047};
KW Receptor {ECO:0000256|RuleBase:RU000688, ECO:0000313|EMBL:ELW66838.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000011518};
KW Sensory transduction {ECO:0000256|RuleBase:RU363047};
KW Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|RuleBase:RU000688};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000688};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU363047}.
FT TRANSMEM 70..97
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363047"
FT TRANSMEM 104..124
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363047"
FT TRANSMEM 144..166
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363047"
FT TRANSMEM 187..208
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363047"
FT TRANSMEM 250..272
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363047"
FT TRANSMEM 284..306
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363047"
FT TRANSMEM 318..338
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363047"
FT DOMAIN 87..336
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
SQ SEQUENCE 366 AA; 40370 MW; D4C6A109AC9AEEC5 CRC64;
MGDEDAYKNQ FSPDMKSSPT ADVAEEVLLY ARTQWKDAKK EGQGRSAMER NNETLTDFIL
LGPWPELSHL VVLICLILLV YFAAVVGNAA LMLLIWLDPR LHSPMYFLLS QLSFIDLALI
STSVPKMVTN FFSGKRTISQ AGCGIQIFFS LTLGIAECLL LTLMSYDRYI TICNPLRYPA
IMSHTACTQM VLGSWVGGAV TSLAHTAYAM HFPICRPRKI PHFLCEVMAL LKLTCEDTSA
YVKSVVVSSF LVVLIPLSLI LASYALILLT VLRMSSPEGR NKALATCSSH LGVVSLYFGP
AILVYMRPGS SKTPGLNQSL FMFNAILTPM LNPLIYSLRN RDVTAALRST VASRCPLRNR
SSLCSC
//
