ID L9KZM3_TUPCH Unreviewed; 438 AA.
AC L9KZM3;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE SubName: Full=BRCA1-associated protein {ECO:0000313|EMBL:ELW66582.1};
GN ORFNames=TREES_T100017077 {ECO:0000313|EMBL:ELW66582.1};
OS Tupaia chinensis (Chinese tree shrew).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Scandentia; Tupaiidae; Tupaia.
OX NCBI_TaxID=246437 {ECO:0000313|EMBL:ELW66582.1, ECO:0000313|Proteomes:UP000011518};
RN [1] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Zhang G., Fan Y., Yao Y., Huang Z.;
RT "Genome of the Chinese tree shrew, a rising model animal genetically
RT related to primates.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23385571; DOI=10.1038/ncomms2416;
RA Fan Y., Huang Z.Y., Cao C.C., Chen C.S., Chen Y.X., Fan D.D., He J.,
RA Hou H.L., Hu L., Hu X.T., Jiang X.T., Lai R., Lang Y.S., Liang B.,
RA Liao S.G., Mu D., Ma Y.Y., Niu Y.Y., Sun X.Q., Xia J.Q., Xiao J.,
RA Xiong Z.Q., Xu L., Yang L., Zhang Y., Zhao W., Zhao X.D., Zheng Y.T.,
RA Zhou J.M., Zhu Y.B., Zhang G.J., Wang J., Yao Y.G.;
RT "Genome of the Chinese tree shrew.";
RL Nat. Commun. 4:1426-1426(2013).
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DR EMBL; KB320648; ELW66582.1; -; Genomic_DNA.
DR AlphaFoldDB; L9KZM3; -.
DR STRING; 246437.L9KZM3; -.
DR eggNOG; KOG0804; Eukaryota.
DR InParanoid; L9KZM3; -.
DR Proteomes; UP000011518; Unassembled WGS sequence.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd16457; RING-H2_BRAP2; 1.
DR CDD; cd12718; RRM_BRAP2; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR011422; BRAP2/ETP1_RRM.
DR InterPro; IPR034932; BRAP2_RRM.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR047243; RING-H2_BRAP2.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR001607; Znf_UBP.
DR PANTHER; PTHR24007; BRCA1-ASSOCIATED PROTEIN; 1.
DR PANTHER; PTHR24007:SF7; BRCA1-ASSOCIATED PROTEIN; 1.
DR Pfam; PF07576; BRAP2; 1.
DR Pfam; PF13639; zf-RING_2; 1.
DR Pfam; PF02148; zf-UBP; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00290; ZnF_UBP; 1.
DR SUPFAM; SSF57850; RING/U-box; 2.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
DR PROSITE; PS50271; ZF_UBP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000011518};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00502}.
FT DOMAIN 110..150
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 147..239
FT /note="UBP-type"
FT /evidence="ECO:0000259|PROSITE:PS50271"
FT REGION 404..438
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 284..353
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 404..427
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 438 AA; 50549 MW; 24651312D645CA72 CRC64;
MTDMIIETMK SNPVPATMTS HDLMKFVAPF NEVIEQMKII RDSTPNQYMV LIKFSAQADA
DSFYMACNGR QFNSIEDDVC QLVYVERAEV LKSEDGASLP VMDLTELPKC TVCLERMDES
VNGILTTLCN HSFHSQCLQR WDDTTCPVCR YCQTPEPVEE NKCFECGVQE NLWICLICGH
IGCGRYVSRH AYKHFEETQH TYAMQLTNHR VWDYAGDNYV HRLVASKTDG KIVQYECEGD
TCQEEKIDAL QLEYSYLLTS QLESQRIYWE NKIVRIEKDT AEEINNMKTK FKETIEKCDN
LEHRLNDLLK EKQSVERKCT QLNTKVAKLT TELKEEQEMN KCLRANQVLL QNKLKEEERV
LKETCDQKDL QITEIQEQLR DVMFYLEAQQ KINHLPAETR QEIQEGQINI PVASASSPSS
SGGSGKLPSR KGRSKRGK
//
