ID L9L3D1_TUPCH Unreviewed; 2099 AA.
AC L9L3D1;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE SubName: Full=Bromodomain and WD repeat-containing protein 1 {ECO:0000313|EMBL:ELW67902.1};
GN ORFNames=TREES_T100007490 {ECO:0000313|EMBL:ELW67902.1};
OS Tupaia chinensis (Chinese tree shrew).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Scandentia; Tupaiidae; Tupaia.
OX NCBI_TaxID=246437 {ECO:0000313|EMBL:ELW67902.1, ECO:0000313|Proteomes:UP000011518};
RN [1] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Zhang G., Fan Y., Yao Y., Huang Z.;
RT "Genome of the Chinese tree shrew, a rising model animal genetically
RT related to primates.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23385571; DOI=10.1038/ncomms2416;
RA Fan Y., Huang Z.Y., Cao C.C., Chen C.S., Chen Y.X., Fan D.D., He J.,
RA Hou H.L., Hu L., Hu X.T., Jiang X.T., Lai R., Lang Y.S., Liang B.,
RA Liao S.G., Mu D., Ma Y.Y., Niu Y.Y., Sun X.Q., Xia J.Q., Xiao J.,
RA Xiong Z.Q., Xu L., Yang L., Zhang Y., Zhao W., Zhao X.D., Zheng Y.T.,
RA Zhou J.M., Zhu Y.B., Zhang G.J., Wang J., Yao Y.G.;
RT "Genome of the Chinese tree shrew.";
RL Nat. Commun. 4:1426-1426(2013).
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DR EMBL; KB320597; ELW67902.1; -; Genomic_DNA.
DR STRING; 246437.L9L3D1; -.
DR InParanoid; L9L3D1; -.
DR Proteomes; UP000011518; Unassembled WGS sequence.
DR CDD; cd05496; Bromo_WDR9_II; 1.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 2.30.30.1040; -; 2.
DR Gene3D; 1.20.920.10; Bromodomain-like; 2.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR018359; Bromodomain_CS.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR16266:SF26; BROMODOMAIN AND WD REPEAT-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR16266; WD REPEAT DOMAIN 9; 1.
DR Pfam; PF00439; Bromodomain; 2.
DR Pfam; PF00400; WD40; 4.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 1.
DR SMART; SM00320; WD40; 6.
DR SUPFAM; SSF47370; Bromodomain; 2.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00633; BROMODOMAIN_1; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 5.
DR PROSITE; PS50294; WD_REPEATS_REGION; 4.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|ARBA:ARBA00023117, ECO:0000256|PROSITE-
KW ProRule:PRU00035}; Reference proteome {ECO:0000313|Proteomes:UP000011518};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 182..223
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 224..265
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 273..314
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 338..372
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 373..415
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 1161..1231
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT REGION 571..598
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 666..798
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1265..1427
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1508..1537
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1592..1635
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1649..1680
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1694..1739
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1826..1894
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1940..2010
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 681..708
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 711..727
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 728..773
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1270..1284
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1301..1340
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1354..1384
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1393..1420
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1508..1530
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1602..1617
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1618..1635
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1649..1674
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1696..1711
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1722..1736
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1836..1850
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1867..1886
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1952..1971
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1972..2000
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2099 AA; 238289 MW; F1C489EBFB4C6F9C CRC64;
MAEPSPARRP VPLIESELYF LIARYLSAGP CRRAAQVLVQ ELEQYQLLPK RLDWEGNEHN
RSYEELVLSN KHVAPDHLLQ ICQRIGPMLD KEIPPSISRV TSLLGAGRQS LLRTAKDCRH
TVWKGSAFAA LHRGRPPEMP VNYGSPPNLV EIHRGKQLTG CSTFSTAFPG TMYQHIKMHR
RILGHLSAVY CVAFDRTGHR IFTGSDDCLV KIWSTHNGRL LSTLRGHSAE ISDMAVNYEN
TMIAAGSCDK IIRVWCLRTC APVAVLHGHT GSITSLQDKV DSIQFCNNGD RFLSGSRDGT
ARVWRFEQSE WRSVVLDMAT RISGDLSSEE ERFMKPKVTM IAWNQNDSIV VTAVNDHVLK
VWNSYTGQLL HNLLGHADEV FVLETHPFDS RIMLSAGHDG SIFIWDVTKG TKMKHYFNMI
EGQGHGAVFD CKFSQDGQHF ACTDSHGHLL IFGFGCSKPY EKIPDQMFFH TDYRPLIRDS
NNYVLDEQTQ QAPHLMPPPF LVDVDGNPHP TKYQRLVPGR ENSADEHLVP QLGYVATSDG
EVIEQIISLQ TNDNGEQSPE SSILDGMIRQ LQQQQDQRMG ADQDTIPSGL PNGEETPRRG
FRRLSLDIQS PPNIGLRRSG QVEGVRQMHQ NAPRSQIATE RDLQAWKRRV VVPEWNSVVL
ASQSKQRTCR RRKYPTYSRR NLSRHEISSG NESSSSIRQE TSCDPSDGSC SSDEDEWKSD
RKSESYSESS SDSSSRYSDW TADAGINLQP PLRTSSRRRV TRFFSSSEDE MSAENLSPPK
RRRKRKKESK PKKENLQRMT PAELMNVDHL YEFHPPVWIT DTTLRKSPFV PQMGDEVIYF
RQGHEAYIEA VRRNNIYEVN PNKEPWRKMD LRFYDEARQR NWQSCDRFRS IIDDAWWFGT
VLSQEPYQPQ YPDSHFQCYI VRWDNTEIEK LSPWDMEPIP DNGDRFRSII DDAWWFGTVL
SQEPYQPQYP DSHFQCYIVR WDNTEIEKLS PWDMEPIPDN VDPPEELGAS ISVTSDELEK
LLYKPQDGEW GQKSRDEECD RIISGIDQLL NLDIAAAFAG PVDLCTYPKY CTVVAYPTDL
YTIRMRLVNR FYRNQDCTNI SELSNISENE QITEDLDDSD LPKTSSGRRR VHDWKKRSSK
AADYVESNWK KQCKELVSLI FQCEDSEPFR QPVDLVEYPD YRDIIDTPMD FGTVRETLEA
GNYDSPLEFC KDIRLIFSNA KAYTPNKRSK IYSMTLRLSA LFEEKMKKIS SDFKIGQKFN
EKLRRSKRFK QQQNCNSVNK GNRSSRNIKQ KRLKSQTEVV PELVDSPTQS TSSRVAYSTT
HETSAGVFSG VTSGDSSDSI GSSERMRRHR PVTLTNGSPL SESEMEDSLA TSSSSSTSNS
SEESKESSRT LESSFRRGPS RSSNLRATRT RATQRKTGPV SLENGCGRKA TRKRVYLSDS
DNNSLDTGEI LKARARSNRK VLRKCAAVAA NKIKLMSDVE ENSSSESVCS GRKLPHRNAS
AVARRKLLHN SEDDQSLKSE FEEEELKDQT HSSPVSNILA TQNTISESEN GDSESESDLR
VARKNWHANG FKSHIPSTSK TKFLKIVSSE EECKSHDSDS VRNRTAGPST SGQKLKAENT
SEEADSEPGK CSKKYNTFHK DANLFKTKIL SDSEDSESEE HDKEDGRCHK KEMNPTSGNL
KCAPIEISQC FSDHVSETDQ DSDDGKAKKN ANLMKDSTSQ DSGQRKVSRK RVCSSDSDSN
SKVVTKLSKA KTGFLRITRR CASTAANKIK LLSDAEDDCL GNVCTRSRNR RKKTLQFVCP
TAKKVVSDCE GGINCEVPNE RYACEGKLPE PDSEGSAKSV SPSLHGDSDS EGILNSEHKN
RHTSNHKTNV PSKTKNSSIG SSEEDSKSHI PGNEIGRKFS AESTWAQKAT AENNFEEELN
YGLRRWNGRR LRTYGKAPFS KTKVVQDSQE SPGMEIKRKR LHPELESVNI SERTRSSKFG
PDTSPKSSDL ESVTESDIDC TNNTKTKRRK TKGKTKVVRK GKTFTANLSK TVRRQRQSKR
PRLNVDDNDW EDLDYAKSKR VLRRSKIKTR NQGRRTVRYH DGDDDRSVEN VLDFNDCTL
//
