ID L9L9L9_TUPCH Unreviewed; 740 AA.
AC L9L9L9;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE SubName: Full=GAS2-like protein 3 {ECO:0000313|EMBL:ELW71573.1};
GN ORFNames=TREES_T100002533 {ECO:0000313|EMBL:ELW71573.1};
OS Tupaia chinensis (Chinese tree shrew).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Scandentia; Tupaiidae; Tupaia.
OX NCBI_TaxID=246437 {ECO:0000313|EMBL:ELW71573.1, ECO:0000313|Proteomes:UP000011518};
RN [1] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Zhang G., Fan Y., Yao Y., Huang Z.;
RT "Genome of the Chinese tree shrew, a rising model animal genetically
RT related to primates.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23385571; DOI=10.1038/ncomms2416;
RA Fan Y., Huang Z.Y., Cao C.C., Chen C.S., Chen Y.X., Fan D.D., He J.,
RA Hou H.L., Hu L., Hu X.T., Jiang X.T., Lai R., Lang Y.S., Liang B.,
RA Liao S.G., Mu D., Ma Y.Y., Niu Y.Y., Sun X.Q., Xia J.Q., Xiao J.,
RA Xiong Z.Q., Xu L., Yang L., Zhang Y., Zhao W., Zhao X.D., Zheng Y.T.,
RA Zhou J.M., Zhu Y.B., Zhang G.J., Wang J., Yao Y.G.;
RT "Genome of the Chinese tree shrew.";
RL Nat. Commun. 4:1426-1426(2013).
CC -!- SIMILARITY: Belongs to the GAS2 family.
CC {ECO:0000256|ARBA:ARBA00038441}.
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DR EMBL; KB320459; ELW71573.1; -; Genomic_DNA.
DR AlphaFoldDB; L9L9L9; -.
DR STRING; 246437.L9L9L9; -.
DR eggNOG; KOG0516; Eukaryota.
DR InParanoid; L9L9L9; -.
DR Proteomes; UP000011518; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR CDD; cd21269; CH_GAS2L3; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR Gene3D; 3.30.920.20; Gas2-like domain; 2.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR003108; GAR_dom.
DR InterPro; IPR036534; GAR_dom_sf.
DR PANTHER; PTHR46756:SF7; GAS2-LIKE PROTEIN 3; 1.
DR PANTHER; PTHR46756; TRANSGELIN; 1.
DR Pfam; PF00307; CH; 1.
DR Pfam; PF02187; GAS2; 2.
DR SMART; SM00033; CH; 1.
DR SMART; SM00243; GAS2; 2.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF143575; GAS2 domain-like; 2.
DR PROSITE; PS50021; CH; 1.
DR PROSITE; PS51460; GAR; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Reference proteome {ECO:0000313|Proteomes:UP000011518}.
FT DOMAIN 59..179
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 255..328
FT /note="GAR"
FT /evidence="ECO:0000259|PROSITE:PS51460"
FT REGION 376..740
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 403..434
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 444..482
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 515..531
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 536..614
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 631..681
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 709..734
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 740 AA; 81067 MW; BDC4B3E7193A1B9D CRC64;
MAFNKGAFIH SNRCFLQVWF GEDLPLSPRS PLTPRHGPGL ADVCQYDEWI AVRHEATLLP
MQEDLSIWLS GLLGIEIKAE KLLEELDNGV LLCQLIDVLQ NMVKTYNSEE PENFPMRKVP
CKKDAASGSF FARDNTANFL HWCRHIGVDE TYLFESEGLV LHKDPRQVYL CLLEIGRIVS
RYGVEPPVLV KLEKEIELEE TLLNTSGPED SISIPKSCCQ HEELHEAVKH IAEDPPCSCS
HRFSIEYLSE GRYRLGDKIL FIRVKHIAED PPCSCSHRFS IEYLSEGRYR LGDKILFIRM
LHGKHVMVRV GGGWDTLQGF LLKYDPCRIL QFATLEQKIL AFQKGVSNES VPDFPSRTPQ
PPEMNPLSAV HMFQKQNPKP GTAADISRSK GKQVRPQGVP LPASSLNGEN LDSVTVRSKF
PNPPAASSPL KLKSSKGITK KPHAPSKNVS SSLALNPVGK STSSPALSRT APCVSGSLRK
CNASPKTPKA KVLPAHNSVG RPETTLLPKT CSGKTEPKYL KHNRTSPRDD AVLHSAVHLN
SSSKCPKQPK TNTRVRPQPS PSSQSPATVT KPSSKTAGLR MQSKPSERAP QAVTVPTQKL
RSPLNLNQPV SAPSVSPPKA TPKLKDKTTV SFAKKQPQNK SSACQKTGSS SSKSPGRTPL
SIMSLPQSSA KTQTALKSAQ MASKGQHGAR GLPRNGKAPA ATRKPPSSAK EADSGDKAAA
KKKEDDDHYF VMTGSKKPRK
//
