ID L9L9U9_TUPCH Unreviewed; 534 AA.
AC L9L9U9;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Transcription factor AP-2-alpha {ECO:0000313|EMBL:ELW71746.1};
GN ORFNames=TREES_T100000133 {ECO:0000313|EMBL:ELW71746.1};
OS Tupaia chinensis (Chinese tree shrew).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Scandentia; Tupaiidae; Tupaia.
OX NCBI_TaxID=246437 {ECO:0000313|EMBL:ELW71746.1, ECO:0000313|Proteomes:UP000011518};
RN [1] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Zhang G., Fan Y., Yao Y., Huang Z.;
RT "Genome of the Chinese tree shrew, a rising model animal genetically
RT related to primates.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23385571; DOI=10.1038/ncomms2416;
RA Fan Y., Huang Z.Y., Cao C.C., Chen C.S., Chen Y.X., Fan D.D., He J.,
RA Hou H.L., Hu L., Hu X.T., Jiang X.T., Lai R., Lang Y.S., Liang B.,
RA Liao S.G., Mu D., Ma Y.Y., Niu Y.Y., Sun X.Q., Xia J.Q., Xiao J.,
RA Xiong Z.Q., Xu L., Yang L., Zhang Y., Zhao W., Zhao X.D., Zheng Y.T.,
RA Zhou J.M., Zhu Y.B., Zhang G.J., Wang J., Yao Y.G.;
RT "Genome of the Chinese tree shrew.";
RL Nat. Commun. 4:1426-1426(2013).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the AP-2 family.
CC {ECO:0000256|ARBA:ARBA00007770}.
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DR EMBL; KB320453; ELW71746.1; -; Genomic_DNA.
DR AlphaFoldDB; L9L9U9; -.
DR STRING; 246437.L9L9U9; -.
DR InParanoid; L9L9U9; -.
DR Proteomes; UP000011518; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005840; C:ribosome; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0019843; F:rRNA binding; IEA:InterPro.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:InterPro.
DR Gene3D; 3.90.930.12; Ribosomal protein L6, alpha-beta domain; 1.
DR InterPro; IPR036789; Ribosomal_uL6-like_a/b-dom_sf.
DR InterPro; IPR004979; TF_AP2.
DR InterPro; IPR013854; TF_AP2_C.
DR PANTHER; PTHR10812; TRANSCRIPTION FACTOR AP-2; 1.
DR PANTHER; PTHR10812:SF8; TRANSCRIPTION FACTOR AP-2-ALPHA; 1.
DR Pfam; PF03299; TF_AP-2; 1.
DR PRINTS; PR01748; AP2TNSCPFCT.
DR SUPFAM; SSF56053; Ribosomal protein L6; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000011518};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 308..502
FT /note="Transcription factor AP-2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03299"
FT REGION 52..118
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 197..267
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 512..534
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 67..118
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 230..248
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 534 AA; 57956 MW; 0F8667FB10C80E53 CRC64;
MKTTLSKQTV YMPENVDIAL KGHTAIVKGR RRTLQTDCNH IHVELSLLGK KKKRLQDRHD
GASNGTARLP QLGTPIYPQS QDPYSHVNDP YSLNPLHAQP QPQHPGWPGQ RQSQESGLLH
THRGLPHQLS GLDPRRDYRR HEDLLHGPHG LGSGLGDLSI HSLPHAIEDV PHVEDPGINI
PDQTVIKKDC TLGGEGQGWL GTGQGLRATG PRDPGSGMEQ GTGRELGSRG KNYRISELDR
RRSRGCSAGR GEGRAGQDLG GSSTPTRGLR CVSAGPVSLS KSNSNAVSAI PINKDNLFGG
VVNPNEVFCS VPGRLSLLSS TSKYKVTVAE VQRRLSPPEC LNASLLGGVL RRAKSKNGGR
SLREKLDKIG LNLPAGRRKA ANVTLLTSLV EGEAVHLARD FGYVCETEFP AKAVAEFLNR
QHSDPNEQVT RKNMLLATKQ ICKEFTDLLA QDRSPLGNSR PNPILEPGIQ SCLTHFNLIS
HGFGSPAVCA AVTALQNYLT EALKAMDKMY LSSSPNSHTD NSAKSSDKEE KHRK
//
