ID L9LB67_TUPCH Unreviewed; 853 AA.
AC L9LB67;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE SubName: Full=Integrator complex subunit 6 {ECO:0000313|EMBL:ELW72330.1};
GN ORFNames=TREES_T100015524 {ECO:0000313|EMBL:ELW72330.1};
OS Tupaia chinensis (Chinese tree shrew).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Scandentia; Tupaiidae; Tupaia.
OX NCBI_TaxID=246437 {ECO:0000313|EMBL:ELW72330.1, ECO:0000313|Proteomes:UP000011518};
RN [1] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Zhang G., Fan Y., Yao Y., Huang Z.;
RT "Genome of the Chinese tree shrew, a rising model animal genetically
RT related to primates.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23385571; DOI=10.1038/ncomms2416;
RA Fan Y., Huang Z.Y., Cao C.C., Chen C.S., Chen Y.X., Fan D.D., He J.,
RA Hou H.L., Hu L., Hu X.T., Jiang X.T., Lai R., Lang Y.S., Liang B.,
RA Liao S.G., Mu D., Ma Y.Y., Niu Y.Y., Sun X.Q., Xia J.Q., Xiao J.,
RA Xiong Z.Q., Xu L., Yang L., Zhang Y., Zhao W., Zhao X.D., Zheng Y.T.,
RA Zhou J.M., Zhu Y.B., Zhang G.J., Wang J., Yao Y.G.;
RT "Genome of the Chinese tree shrew.";
RL Nat. Commun. 4:1426-1426(2013).
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DR EMBL; KB320426; ELW72330.1; -; Genomic_DNA.
DR AlphaFoldDB; L9LB67; -.
DR STRING; 246437.L9LB67; -.
DR eggNOG; KOG3768; Eukaryota.
DR InParanoid; L9LB67; -.
DR Proteomes; UP000011518; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd00198; vWFA; 1.
DR Gene3D; 3.30.70.330; -; 2.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR029307; INT_SG_DDX_CT_C.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR12957; DEAD/H BOX POLYPEPTIDE 26/DICE1-RELATED; 1.
DR PANTHER; PTHR12957:SF23; INTEGRATOR COMPLEX SUBUNIT 6; 1.
DR Pfam; PF15300; INT_SG_DDX_CT_C; 1.
DR Pfam; PF00076; RRM_1; 1.
DR Pfam; PF13519; VWA_2; 1.
DR SMART; SM00360; RRM; 2.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50102; RRM; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000011518};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176}.
FT DOMAIN 549..591
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
SQ SEQUENCE 853 AA; 96646 MW; FC0C125E982DF2FE CRC64;
MPILLFLIDT SASMNQRSHL GTTYLDTAKG AVETFMKLRA RDPASRGDRY MLVTFEEPPY
AIKAGWKENH ATFMNELKNL QAEGLTTLGQ SLRTAFDLLN LNRLVTGIDN YGQLHLPLNS
PLPGSELTKE PFRWDQRLFA LVLRLPGTMS VESEQLTGVP LDDSAITPMC EVTGGRSYSV
CSPRMLNQCL ESLVQKVQSG VVINFEKAGP DPSPVEVKFS CTDCEPMVID KLPFDKYELE
PSPLTQFILE RKSPQTCWQP LKKAVRMMGA PNLIADSMEY GLSYSVISYL KKLSQQAKIE
SDRVIGSVGK KVVQETGIKV RSRSHGLSMA YRKDFQQLLQ GISEDVPHRL LDLNMKEYTG
FQVALLNKDL KPQTFRNAYD IPRRNLLDHL TRMRSNLLKS TRRFLKGQDE DQVHSVPIAQ
MGNYQEYLKQ VPSPLRELDP DQPRRLHTFG NPFKLDKKGM MIDEADEFVA GPQNKHKRPG
EPNMQGIPKR RRCMSPLLRG RQQNPVVNNH IGGKGPPTPM SQAQPDLIKP LPLHKREEGH
DPKELEQLRK LFIGGLSFET TDDSLREHFE KWGTLTDCVV MRDPQKKRSQ GGRGGCTVCA
RPHKVDGCVV EPKRAVSRDD SVKPGVHLTV KKIFVGGIKE DTEEYNLGGY FEKFGKIEII
EVMEDRQISE ATNDSIVDDV VENHVADQLS SEITPNAMDT EFSTSSPANL LERPTNHTEA
LGHDHLGTND LNIGGFLENH EEPRDKEQCA EENIPASSLN KGKKLVHCRS HEEVNTELKA
QIMKEIRKPG RKYERIFTLL KHVQGSLQTR LIFLQNVIKE ASRFKKRMLI EQLENFLDEI
HRRANQINHI NSN
//
