ID L9X4N8_9EURY Unreviewed; 950 AA.
AC L9X4N8;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 24-JAN-2024, entry version 54.
DE SubName: Full=PAS sensor protein {ECO:0000313|EMBL:ELY56754.1};
GN ORFNames=C491_12145 {ECO:0000313|EMBL:ELY56754.1};
OS Natronococcus amylolyticus DSM 10524.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC Natrialbaceae; Natronococcus.
OX NCBI_TaxID=1227497 {ECO:0000313|EMBL:ELY56754.1, ECO:0000313|Proteomes:UP000011688};
RN [1] {ECO:0000313|EMBL:ELY56754.1, ECO:0000313|Proteomes:UP000011688}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 10524 {ECO:0000313|EMBL:ELY56754.1,
RC ECO:0000313|Proteomes:UP000011688};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00169}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELY56754.1}.
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DR EMBL; AOIB01000026; ELY56754.1; -; Genomic_DNA.
DR RefSeq; WP_005556563.1; NZ_AOIB01000026.1.
DR AlphaFoldDB; L9X4N8; -.
DR STRING; 1227497.C491_12145; -.
DR PATRIC; fig|1227497.3.peg.2509; -.
DR eggNOG; arCOG02276; Archaea.
DR eggNOG; arCOG02333; Archaea.
DR OrthoDB; 165911at2157; -.
DR Proteomes; UP000011688; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 3.30.450.40; -; 2.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR031803; BAT_GAF/HTH-assoc.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR007050; HTH_bacterioopsin.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR34236; DIMETHYL SULFOXIDE REDUCTASE TRANSCRIPTIONAL ACTIVATOR; 1.
DR PANTHER; PTHR34236:SF1; DIMETHYL SULFOXIDE REDUCTASE TRANSCRIPTIONAL ACTIVATOR; 1.
DR Pfam; PF15915; BAT; 1.
DR Pfam; PF13185; GAF_2; 2.
DR Pfam; PF04967; HTH_10; 1.
DR Pfam; PF08448; PAS_4; 1.
DR Pfam; PF00072; Response_reg; 1.
DR SMART; SM00065; GAF; 2.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF55781; GAF domain-like; 2.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR SUPFAM; SSF88659; Sigma3 and sigma4 domains of RNA polymerase sigma factors; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 10..124
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 209..262
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 263..318
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
SQ SEQUENCE 950 AA; 104054 MW; 5D8EA1A07C17C76C CRC64;
MASVRTRDDS RLLVVETGAE TPLTDRVREL ESDEVRSVPD VGTALETLSA TEIDCVVTAQ
RLDGTTGLEL LERLRECNPA LPVVLVPEEG NEGLASDAVA AGVTEYLPLC GLDELESTID
RALSTGTAER RRRERARQFE SIFADPDAYS WTLDPDGRIR RANEAALEAL DAGADESIDR
SFATLSWWES EAVIGEAIDR AAAGTIARRE LEVSVDGGRG TEPRTLDVTV RPVRDETGAV
VSLFARAVDV TERVRLETEL RQSEELHRVT LNHMTDTVLI TDDEGAFTYV CPNVHFIFGY
TDDQIHEMGT IDELLGPELF DREALAAEGV LTNIECTATD RAGREHSLLV NVREVSIQDG
TMLYSCRDIT TRKRREEALT ALHGTARELL YAETEPEIAD RIVADATDVL DLEASAALRF
DTDENVLRPV AASSGMDRLH GPLPTRRAND DSISGQVFLT GEAQFFGDVR ESPTLSDPTT
ELRSVGFVPL GDHGVFVVGS PEVDAFDEVS RELTELLAAT AEAALDRVER ERHLRDRDRE
LKRRNQQLTR LNRMNEIIRE IDAALVGAET REEIERAVCE RLTAAERFAF AWIGAADAAG
ERLESSAHDG SGRGREYLDS VSLSLAEPTE PAARTAASRE VTVVPNVVDE LHDEPWRRAA
LSRDYQSAIA VPLAYDEFTY GVLTVYADRP DAFDDTTRAV LAELGETIAA AIAAVERKRA
LLSDSRTRLE FDVADEEFVF ARLARRLDCV LSFDGGVRQH EGTVAVFVTV DGAAAEDVAA
AATDLVAVED AQTVGDGDGS TVLLELSRPF LALRLADHGI VLHRLEATPE TTRLVVDVPS
SVDPAASADV VANAFTDVEL RSKRTVERTA PRDLRSELLD RLTDRQLEVV QMAYYGGYFE
SPRERSGAEI AETLGISSAA FYRHVRRVQR TLFAVLLEET GLPAVPSAGG
//
