ID L9X9T6_9EURY Unreviewed; 409 AA.
AC L9X9T6;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=ORC1-type DNA replication protein {ECO:0000256|HAMAP-Rule:MF_01407};
GN ORFNames=C491_08579 {ECO:0000313|EMBL:ELY58377.1};
OS Natronococcus amylolyticus DSM 10524.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC Natrialbaceae; Natronococcus.
OX NCBI_TaxID=1227497 {ECO:0000313|EMBL:ELY58377.1, ECO:0000313|Proteomes:UP000011688};
RN [1] {ECO:0000313|EMBL:ELY58377.1, ECO:0000313|Proteomes:UP000011688}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 10524 {ECO:0000313|EMBL:ELY58377.1,
RC ECO:0000313|Proteomes:UP000011688};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
CC -!- FUNCTION: Involved in regulation of DNA replication.
CC {ECO:0000256|HAMAP-Rule:MF_01407}.
CC -!- SIMILARITY: Belongs to the CDC6/cdc18 family. {ECO:0000256|HAMAP-
CC Rule:MF_01407}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELY58377.1}.
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DR EMBL; AOIB01000020; ELY58377.1; -; Genomic_DNA.
DR RefSeq; WP_005555237.1; NZ_AOIB01000020.1.
DR AlphaFoldDB; L9X9T6; -.
DR STRING; 1227497.C491_08579; -.
DR PATRIC; fig|1227497.3.peg.1765; -.
DR eggNOG; arCOG00467; Archaea.
DR OrthoDB; 195574at2157; -.
DR Proteomes; UP000011688; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR CDD; cd00009; AAA; 1.
DR CDD; cd08768; Cdc6_C; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR HAMAP; MF_01407; ORC1_type_DNA_replic_protein; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR015163; Cdc6_C.
DR InterPro; IPR014277; Orc1/Cdc6_arc.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR02928; orc1/cdc6 family replication initiation protein; 1.
DR PANTHER; PTHR10763; CELL DIVISION CONTROL PROTEIN 6-RELATED; 1.
DR PANTHER; PTHR10763:SF22; ORC1-TYPE DNA REPLICATION PROTEIN 3; 1.
DR Pfam; PF13401; AAA_22; 1.
DR Pfam; PF09079; Cdc6_C; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM01074; Cdc6_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|HAMAP-
KW Rule:MF_01407};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705, ECO:0000256|HAMAP-
KW Rule:MF_01407};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|HAMAP-
KW Rule:MF_01407}.
FT DOMAIN 57..219
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 312..396
FT /note="Cdc6 C-terminal"
FT /evidence="ECO:0000259|SMART:SM01074"
FT BINDING 69..73
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01407"
FT BINDING 218
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01407"
FT BINDING 230
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01407"
SQ SEQUENCE 409 AA; 46099 MW; 276553C9816B8E05 CRC64;
MSANDDRDPL FRYDDPIFAD ERLLEITHLP GPDRIVGRDE QMQRVADALN PAIFGSEPNH
LFIFGKTGTG KSLISRSVTK RVISEAKRDD VTVNYAFIDC GEQNTEASIV KTIAQLVNDP
EQSGITVPDR GLGTGDYYKR LWQAVDRCTD VTIVILDEID MLENDEVLRK LSRAGENRRI
SDSSIGIIGI SNKIDFPDHL SERVKSSLSR DELVFSPYDA NQLVEILEKR RDAFHDEVLS
GDVIPLTAAL AAQEHGDARK AIDILRNAGR IAKKQNADRV TADHVRDAKE KTEADRFNEL
IEGSPQQAKA ILYSLTLLTE NSSEKEFPTK IIYNQYKEVA RRLDFDVLSE RRVQEILQEQ
NFLNVIQSER EGRGRGRGAH AKHRLLENPA IVKKVLLRDS RLAPLESDS
//
