ID   L9ZNI6_9EURY            Unreviewed;      1288 AA.
AC   L9ZNI6;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   24-JAN-2024, entry version 46.
DE   SubName: Full=PAS/PAC sensor protein {ECO:0000313|EMBL:ELY87924.1};
GN   ORFNames=C483_16493 {ECO:0000313|EMBL:ELY87924.1};
OS   Natrialba hulunbeirensis JCM 10989.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC   Natrialbaceae; Natrialba.
OX   NCBI_TaxID=1227493 {ECO:0000313|EMBL:ELY87924.1, ECO:0000313|Proteomes:UP000011519};
RN   [1] {ECO:0000313|EMBL:ELY87924.1, ECO:0000313|Proteomes:UP000011519}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 10989 {ECO:0000313|EMBL:ELY87924.1,
RC   ECO:0000313|Proteomes:UP000011519};
RX   PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA   Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA   Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT   "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT   strategies for static and dynamic osmo-response.";
RL   PLoS Genet. 10:E1004784-E1004784(2014).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ELY87924.1}.
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DR   EMBL; AOIM01000040; ELY87924.1; -; Genomic_DNA.
DR   RefSeq; WP_006654437.1; NZ_AOIM01000040.1.
DR   STRING; 1227493.C483_16493; -.
DR   PATRIC; fig|1227493.4.peg.3316; -.
DR   OrthoDB; 186758at2157; -.
DR   Proteomes; UP000011519; Unassembled WGS sequence.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 3.30.450.40; -; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 3.
DR   InterPro; IPR031803; BAT_GAF/HTH-assoc.
DR   InterPro; IPR003018; GAF.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR007050; HTH_bacterioopsin.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013767; PAS_fold.
DR   NCBIfam; TIGR00229; sensory_box; 1.
DR   PANTHER; PTHR34236; DIMETHYL SULFOXIDE REDUCTASE TRANSCRIPTIONAL ACTIVATOR; 1.
DR   PANTHER; PTHR34236:SF1; DIMETHYL SULFOXIDE REDUCTASE TRANSCRIPTIONAL ACTIVATOR; 1.
DR   Pfam; PF15915; BAT; 2.
DR   Pfam; PF13185; GAF_2; 1.
DR   Pfam; PF04967; HTH_10; 1.
DR   Pfam; PF00989; PAS; 1.
DR   Pfam; PF13188; PAS_8; 1.
DR   SMART; SM00091; PAS; 3.
DR   SUPFAM; SSF55781; GAF domain-like; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR   PROSITE; PS50112; PAS; 1.
PE   4: Predicted;
KW   Transcription {ECO:0000256|ARBA:ARBA00023015};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          171..241
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   REGION          374..408
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          608..701
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          838..868
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1058..1113
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        657..691
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        850..868
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1059..1073
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1089..1103
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1288 AA;  137137 MW;  A62FE34BCAFF15F9 CRC64;
     MSDRNRDRNR PAAATTDGPT ILVVGDSHRL DRTADTLASV LESTAMRQAP RTDVAREYLA
     TTTGAQAAAD PPSPVHCLVC EFSTDATEES RLAELTALES DDAGDGFVTD LPPIVALAAP
     DDAEAALDAG ATDVFTPADP AAVVAARVKS VADRQRAVWE AERTRREQRS RSERTQTILQ
     NTTAPILVLT ETGEIRTATP AIESQTGHAP PVLEGERLSA FVHPDDRERL RHAVAAVADG
     SVGATERVRL RLRTAGGTWR VVELVCVSRL SDPTLEGIVA TVEPARLAHD GDDPAETDER
     TALDGLPVAC CSLGPDWELQ WANDAARRFL RGAGNEQSDG VRARGALEDT VIWDLLPAAL
     RETFYERLHE ASATETPVQF ETPSPAESSV VDPAPASTEA DNQSNDTGRL LVTAAPDRNG
     VTLSIHESRS DTLGETTAPP LPAADRERLA LLSELVDALQ DGVAVLDDDT VEFANTALCE
     LADTDSLAGT AVEALFDDDL AAAVLERANA PVIRWMDAVE GELLGSRGDR QPVDVLVTPL
     SAADRTLCVV RDRRQSAAGS LSRLAAMLDS LDAVDSRTAV YQTVVDGVRA EAGGEFAGWY
     RLERAEEAEE AAEAAESAGA DTPDDPRFRP VAIATGPNVP RIDPPPVERD ALAFVNDEGD
     ESDEDGEGDE GSEDDDENEG REDDENDESS EPTDPPTVRL VDDTTASSFL SRSGLRAARV
     LAVPITDEDV VVVTGSDPLA FDALDTEPVA SLAAAGSVAL ESTLARERSR ESHRERERLA
     GALSVADAVM AAERELLAAE SRDAVEQRLC EVVGKLPTAG EVGVGEVGEM GKIGERAEMS
     EEDESDKVSE ANNITPASTP APVSEFTAPT TTPSLVWFGR IDAGSETVTP QAWAGDRAAV
     LDAGGDADRP SLTVDSSTVL PAARTGATQT PTVVDDYTAL ADSELDSTGR AWYRTLRDAG
     VRSVVSVPVE YGGISYGTLT VYADRPDAFD ERTRRAYSHL GDVAGYAIGA LARTQALLTD
     RVTELEVVLR ESNDPLAQVA SRLGRGLDVR AVVPRSGGGS TVYCTTRNTD ADGETDAAPT
     GDSDSVDVAE DGDANRRVNA DEPLSPRLES ATDLEGVASA RLVGDEPDQT DHGDDSVQPG
     SPLEVVLESE SLADVLAAHG GVLHSVMPLD GRTRLVLTVP GSDSATTPVR SIVERLEREA
     VSARLLARRE RDARPRSVRA FDAELRERLS DRQWRTLEAA YYGGFFAWPR ESTGEEIADS
     LAVSQPTFSR HLRAAQRKLF ELLFDQSA
//