ID LRC63_RAT Reviewed; 607 AA.
AC Q4V8G0;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2005, sequence version 1.
DT 27-MAR-2024, entry version 103.
DE RecName: Full=Leucine-rich repeat-containing protein 63;
GN Name=Lrrc63;
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Testis;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
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DR EMBL; BC097406; AAH97406.1; -; mRNA.
DR RefSeq; NP_001019974.1; NM_001024803.1.
DR RefSeq; XP_006252387.1; XM_006252325.3.
DR RefSeq; XP_006252388.1; XM_006252326.3.
DR RefSeq; XP_006252389.1; XM_006252327.3.
DR AlphaFoldDB; Q4V8G0; -.
DR SMR; Q4V8G0; -.
DR STRING; 10116.ENSRNOP00000072416; -.
DR PhosphoSitePlus; Q4V8G0; -.
DR PaxDb; 10116-ENSRNOP00000055096; -.
DR Ensembl; ENSRNOT00000058294.3; ENSRNOP00000055096.2; ENSRNOG00000038291.4.
DR Ensembl; ENSRNOT00065014352; ENSRNOP00065010748; ENSRNOG00065008980.
DR GeneID; 364427; -.
DR KEGG; rno:364427; -.
DR UCSC; RGD:1559507; rat.
DR AGR; RGD:1559507; -.
DR CTD; 220416; -.
DR RGD; 1559507; Lrrc63.
DR eggNOG; KOG0619; Eukaryota.
DR GeneTree; ENSGT00710000106860; -.
DR HOGENOM; CLU_027651_0_0_1; -.
DR InParanoid; Q4V8G0; -.
DR OMA; YWHIPET; -.
DR OrthoDB; 2912047at2759; -.
DR PhylomeDB; Q4V8G0; -.
DR TreeFam; TF329649; -.
DR PRO; PR:Q4V8G0; -.
DR Proteomes; UP000002494; Chromosome 15.
DR Bgee; ENSRNOG00000038291; Expressed in testis and 2 other cell types or tissues.
DR ExpressionAtlas; Q4V8G0; baseline.
DR GO; GO:0007165; P:signal transduction; IBA:GO_Central.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR45752; LEUCINE-RICH REPEAT-CONTAINING; 1.
DR PANTHER; PTHR45752:SF21; LEUCINE-RICH REPEAT-CONTAINING PROTEIN 63; 1.
DR Pfam; PF00560; LRR_1; 1.
DR Pfam; PF13855; LRR_8; 1.
DR SMART; SM00369; LRR_TYP; 4.
DR SUPFAM; SSF52047; RNI-like; 1.
DR PROSITE; PS51450; LRR; 4.
PE 2: Evidence at transcript level;
KW Leucine-rich repeat; Reference proteome; Repeat.
FT CHAIN 1..607
FT /note="Leucine-rich repeat-containing protein 63"
FT /id="PRO_0000320630"
FT REPEAT 357..378
FT /note="LRR 1"
FT REPEAT 380..401
FT /note="LRR 2"
FT REPEAT 403..424
FT /note="LRR 3"
FT REPEAT 426..447
FT /note="LRR 4"
FT REPEAT 449..470
FT /note="LRR 5"
FT REPEAT 471..497
FT /note="LRR 6"
FT REPEAT 498..524
FT /note="LRR 7"
SQ SEQUENCE 607 AA; 69217 MW; F45142DA24AB821B CRC64;
MRKRIYHSFK TQQHPLLLRR PLPPKLPKLP LVKKKVRIVQ TGSAREPQEA RRKFDTEESA
LVKIDQSVSQ PQKPASVQNV CLDYEHDEPE RVVNIFPHPH GVRRLHWKVP KSAAGSMFIP
RCLSASSRVF RKTLSQIKRA RKSLKSKQDE DLTKKPFSNT LVISEELSKP LPPSYSRLIA
SRFKHSGTKF RPAPKISHYI QELPLLKDVK ETVLSPISSA SSAIPEPEWS ERPLPKTTIG
KVIQLNTGSL PPAHSLPTPA LPRKPPRQIM IENAVMTRKT ETQKPVEITL RPTRRLDPDA
HVLRGDGFKA VGATRSETIL ALTTLAIINC QIYGRNALNF KGFFLAQCPD LTSVAFQLVY
LNLSYNDLHQ FPGEVLYLQN LQVLKLRNNP IREIPSEIQQ LKYLRKFTIA FNFITSLPAG
LFCLNYLEEL DVSYNEIENI PNEIQKLRSL EKLTVDGTNI TAFPPGILKL NLVKLEFENT
FTIPPFWLEN SCNNPPRLTH ICSLFIVKNN LHKILDYDPV VVQKYLISTS DCDWCHGPKF
GEGFGIIRSC NIFGLSHVPI KFHVCSLSCY LEIRESSFVL EGFPSRRIAL NMDWVKERKV
SNVSFYL
//
