ID M0AH65_NATA1 Unreviewed; 252 AA.
AC M0AH65;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase {ECO:0000313|EMBL:ELY98000.1};
GN ORFNames=C481_18730 {ECO:0000313|EMBL:ELY98000.1};
OS Natrialba asiatica (strain ATCC 700177 / DSM 12278 / JCM 9576 / FERM
OS P-10747 / NBRC 102637 / 172P1).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC Natrialbaceae; Natrialba.
OX NCBI_TaxID=29540 {ECO:0000313|EMBL:ELY98000.1, ECO:0000313|Proteomes:UP000011554};
RN [1] {ECO:0000313|EMBL:ELY98000.1, ECO:0000313|Proteomes:UP000011554}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 12278 {ECO:0000313|EMBL:ELY98000.1,
RC ECO:0000313|Proteomes:UP000011554};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELY98000.1}.
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DR EMBL; AOIO01000040; ELY98000.1; -; Genomic_DNA.
DR RefSeq; WP_006110848.1; NZ_AOIO01000040.1.
DR AlphaFoldDB; M0AH65; -.
DR STRING; 29540.C481_18730; -.
DR PATRIC; fig|29540.5.peg.3818; -.
DR eggNOG; arCOG02465; Archaea.
DR OrthoDB; 372165at2157; -.
DR Proteomes; UP000011554; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR GO; GO:0006189; P:'de novo' IMP biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.1970; -; 1.
DR InterPro; IPR039476; P2CMN_synthase_LarB.
DR InterPro; IPR000031; PurE_dom.
DR NCBIfam; NF033503; LarB; 1.
DR PANTHER; PTHR43064; PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE-RELATED; 1.
DR PANTHER; PTHR43064:SF1; SLL1489 PROTEIN; 1.
DR Pfam; PF00731; AIRC; 1.
DR SMART; SM01001; AIRC; 1.
DR SUPFAM; SSF52255; N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE); 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000011554}.
FT DOMAIN 118..249
FT /note="PurE"
FT /evidence="ECO:0000259|SMART:SM01001"
SQ SEQUENCE 252 AA; 25879 MW; 6CB4534950F80515 CRC64;
MRELLEAVAD GSISPAAAEA ELNGYVTSEA GRFDAARQQR RGIPEAIFAE GKSAAQVVAL
AETALETTGR ALLTRVDDEQ ATALRTALAD SDPEAAIERR HSTVRVLAPT YEPPELDATV
GIVTGGTVDE PVADEAEVVC LDAGATVDRV DDIGVASLAR TLDQVDRFRA ADVLIVAAGR
EGALPTVVAG LVDTPVIAVP VDSGYGYGGD GGAALAGMLQ SCTVLSVVNI DAGFVAGAQA
VLISRAIDRA RR
//
