ID M0AWM2_9EURY Unreviewed; 509 AA.
AC M0AWM2;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Cation transporter {ECO:0000313|EMBL:ELZ02727.1};
GN ORFNames=C482_05151 {ECO:0000313|EMBL:ELZ02727.1};
OS Natrialba chahannaoensis JCM 10990.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC Natrialbaceae; Natrialba.
OX NCBI_TaxID=1227492 {ECO:0000313|EMBL:ELZ02727.1, ECO:0000313|Proteomes:UP000011693};
RN [1] {ECO:0000313|EMBL:ELZ02727.1, ECO:0000313|Proteomes:UP000011693}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 10990 {ECO:0000313|EMBL:ELZ02727.1,
RC ECO:0000313|Proteomes:UP000011693};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004429}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TrkH potassium transport family.
CC {ECO:0000256|ARBA:ARBA00009137}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELZ02727.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AOIN01000036; ELZ02727.1; -; Genomic_DNA.
DR RefSeq; WP_006166393.1; NZ_AOIN01000036.1.
DR AlphaFoldDB; M0AWM2; -.
DR STRING; 1227492.C482_05151; -.
DR PATRIC; fig|1227492.4.peg.994; -.
DR OrthoDB; 111943at2157; -.
DR Proteomes; UP000011693; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015379; F:potassium:chloride symporter activity; IEA:InterPro.
DR InterPro; IPR003445; Cat_transpt.
DR InterPro; IPR004772; TrkH.
DR PANTHER; PTHR32024; TRK SYSTEM POTASSIUM UPTAKE PROTEIN TRKG-RELATED; 1.
DR PANTHER; PTHR32024:SF2; TRK SYSTEM POTASSIUM UPTAKE PROTEIN TRKG-RELATED; 1.
DR Pfam; PF02386; TrkH; 1.
DR PIRSF; PIRSF006247; TrkH; 1.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Potassium {ECO:0000256|ARBA:ARBA00022958};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 12..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 40..59
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 71..91
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 146..174
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 195..215
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 255..277
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 293..311
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 323..342
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 354..379
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 415..435
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 447..464
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 484..507
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 509 AA; 55382 MW; F5A129BDE003835A CRC64;
MRIRVDWRSS CSLTGTVLRW LSIPLAVPAL LAVLDGNDPV PFLVAIAVAI ASGLALEQLS
EDRELGQRES FLMVALTWLG VALVGAIPFL FAGAGSAGDS AFTGLINTPI NAFFESMSGL
TTTGATVMET WDFNNQPRSI LLWRQLIQWL GGLGILIVAI GLLSHLMVGG AQLMETESQT
RNVRKLRPHI SETARLIWGL YVGLTLLAVV VFYGLHLLGF ADGMDLFNAV SHALTSVATA
GFSPEGDSIA AFSPIVQWSI IPFMILGSTN FVLLYYITQG EFERPLQSEE LRFYLGVLAL
FSAIVVAILA FDVELEMGIE PTIRHGVFNV VSLVTTTGYA SMDFNHWSPG AKHMLFLSMF
IGGMAGSTTC SIKSLRWLVV LKAFKRNLFT AIHPEAVRPL RVSGNVVDEE TVNDIFGYVL
LAIVIFFGLT ILLVVDAARA TTDVTEFGAL GAAASIFMNI GPAFELAGPM ENYNDFSAFS
RSVMVIMMWI GRIEIVPVLV LLLPAYWRS
//
