ID   M0E638_9EURY            Unreviewed;       942 AA.
AC   M0E638;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   SubName: Full=Nuclease {ECO:0000313|EMBL:ELZ41824.1};
GN   ORFNames=C472_00696 {ECO:0000313|EMBL:ELZ41824.1};
OS   Halorubrum tebenquichense DSM 14210.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC   Halorubraceae; Halorubrum.
OX   NCBI_TaxID=1227485 {ECO:0000313|EMBL:ELZ41824.1, ECO:0000313|Proteomes:UP000011523};
RN   [1] {ECO:0000313|EMBL:ELZ41824.1, ECO:0000313|Proteomes:UP000011523}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 14210 {ECO:0000313|EMBL:ELZ41824.1,
RC   ECO:0000313|Proteomes:UP000011523};
RX   PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA   Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA   Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT   "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT   strategies for static and dynamic osmo-response.";
RL   PLoS Genet. 10:E1004784-E1004784(2014).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ELZ41824.1}.
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DR   EMBL; AOJD01000004; ELZ41824.1; -; Genomic_DNA.
DR   RefSeq; WP_006627850.1; NZ_AOJD01000004.1.
DR   AlphaFoldDB; M0E638; -.
DR   PATRIC; fig|1227485.3.peg.132; -.
DR   OrthoDB; 3327at2157; -.
DR   Proteomes; UP000011523; Unassembled WGS sequence.
DR   Gene3D; 2.40.50.90; -; 1.
DR   Gene3D; 2.60.40.1260; Lamin Tail domain; 1.
DR   InterPro; IPR025646; DUF4350.
DR   InterPro; IPR001322; Lamin_tail_dom.
DR   InterPro; IPR036415; Lamin_tail_dom_sf.
DR   InterPro; IPR035437; SNase_OB-fold_sf.
DR   InterPro; IPR016071; Staphylococal_nuclease_OB-fold.
DR   Pfam; PF14258; DUF4350; 1.
DR   Pfam; PF00932; LTD; 1.
DR   Pfam; PF00565; SNase; 1.
DR   SMART; SM00318; SNc; 1.
DR   SUPFAM; SSF74853; Lamin A/C globular tail domain; 1.
DR   SUPFAM; SSF50199; Staphylococcal nuclease; 1.
DR   PROSITE; PS51841; LTD; 1.
DR   PROSITE; PS50830; TNASE_3; 1.
PE   4: Predicted;
FT   DOMAIN          429..575
FT                   /note="TNase-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50830"
FT   DOMAIN          833..942
FT                   /note="LTD"
FT                   /evidence="ECO:0000259|PROSITE:PS51841"
SQ   SEQUENCE   942 AA;  97853 MW;  EFC18A622EA97F47 CRC64;
     MRRRSVLIGL GATAAGGGAI ATGAFDTATA ERDATVALAD DASSLLSLTP LDEEFAFVDD
     DGELALVFEE VEGGGTGFGS NTVYEIDEVF QVSNQGTEDL GLFATVDDGN LGDASFDLTV
     DGETLGEDPT VDLGVGEVVA VGVAVDAGDD PTDGEVAITI GIGDGPTEDP GDGPGEAPTE
     FVDELVFDST ASLLAEDGSL PEEAIAVAAE STAASTDADG DGDDTNYPDD APLPLVAVDQ
     DLPVVAFGFP FAQNDVQFVD YGNEEVLLNL LDEYADSDTV LWDEGHDQFY GLDSHSAFAD
     YAGENGYTLE STTDLESDLL GPASAIVITS PSAAFSDDEI GALSSFADAG GLIVLMDQSD
     YSDFDETGNL NALATGLETQ IRFNDNQVID GESNAGSEFA PTTTDLDTGN YPELFADRDG
     LGLELDPNEE YEVEIASVAD GDTADVAFDD GTEETVRILG IDTPETGETE ERLEEYEGID
     DAPALKDEGD EATDYAESEL EVGSTVTLSF DENEGLRGNF GRLLGFLELP DGSVYNANVI
     EAGWARVYDS GLGEHDEYWD LERAARDAGD GIWGISDQAG TDERRDDPVD ELFFPEPVAV
     SGPEEPVASE GGETLVALDP DANVAALGGP LIEESFEGGE GGPGVEAYGV FPFLTNVIDR
     VGDATGPVLV DGGHGQFAAD FAVSAEDAAY YLRYLEGQAP GDEAFVDLEG VVDLATDPGP
     DLLDSDGNPA ARALILSTPT EALSSAERTV VADFADAGGA VVLLGTAADA DALGNFDPVV
     NELDADVTFT GAPVTDAENN LGDPANPTTT NFADGFDGLF TPFTADDGGD GGSGGSLSVV
     EVNADTEGDD LEDPQENVVF ENAGGDALDL TGYTVSDETT KEYSFPDGFS LSSGEQVTLY
     SGEGTDTDAE LYWQSGAKIW NNGGDTVSVT DSDGNVVVEY EY
//