ID   M0EWF7_9EURY            Unreviewed;       246 AA.
AC   M0EWF7;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   SubName: Full=Methyltransferase type 12 {ECO:0000313|EMBL:ELZ52116.1};
GN   ORFNames=C466_12738 {ECO:0000313|EMBL:ELZ52116.1};
OS   Halorubrum distributum JCM 10118.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC   Halorubraceae; Halorubrum; Halorubrum distributum group.
OX   NCBI_TaxID=1227468 {ECO:0000313|EMBL:ELZ52116.1, ECO:0000313|Proteomes:UP000011614};
RN   [1] {ECO:0000313|Proteomes:UP000011614}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 10118 {ECO:0000313|Proteomes:UP000011614};
RA   Becker E.A., Seitzer P., Tritt A., Larsen D., Yao A., Wu D., Darling A.,
RA   Eisen J.A., Facciotti M.T.;
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ELZ52116.1, ECO:0000313|Proteomes:UP000011614}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 10118 {ECO:0000313|EMBL:ELZ52116.1,
RC   ECO:0000313|Proteomes:UP000011614};
RX   PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA   Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA   Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT   "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT   strategies for static and dynamic osmo-response.";
RL   PLoS Genet. 10:E1004784-E1004784(2014).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ELZ52116.1}.
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DR   EMBL; AOJN01000055; ELZ52116.1; -; Genomic_DNA.
DR   RefSeq; WP_004595607.1; NZ_AOJN01000055.1.
DR   AlphaFoldDB; M0EWF7; -.
DR   PATRIC; fig|1227468.4.peg.2507; -.
DR   OrthoDB; 30774at2157; -.
DR   Proteomes; UP000011614; Unassembled WGS sequence.
DR   GO; GO:0031515; C:tRNA (m1A) methyltransferase complex; IEA:InterPro.
DR   GO; GO:0160107; F:tRNA (adenine(58)-N1)-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0030488; P:tRNA methylation; IEA:InterPro.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   InterPro; IPR049470; TRM61_C.
DR   InterPro; IPR014816; tRNA_MeTrfase_Gcd14.
DR   PANTHER; PTHR12133; TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE; 1.
DR   PANTHER; PTHR12133:SF1; TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE, MITOCHONDRIAL; 1.
DR   Pfam; PF08704; GCD14; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR   PROSITE; PS51620; SAM_TRM61; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW   ECO:0000313|EMBL:ELZ52116.1};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:ELZ52116.1};
KW   tRNA processing {ECO:0000256|ARBA:ARBA00022694}.
FT   DOMAIN          74..221
FT                   /note="tRNA (adenine(58)-N(1))-methyltransferase catalytic
FT                   subunit TRM61 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08704"
SQ   SEQUENCE   246 AA;  26099 MW;  325342EF1DB4C5BD CRC64;
     MTDAAYLLVH EDREYLLEPG EEFGTDLGVI EVPEDVAAGD EVETHLGTVF EVRALRGPDL
     FNHLERTGAP MMPRDVGLVM GHTGASGGDR VLDAGTGTGI LAAYLGRAGA DVTTYEVDAE
     FAEVARDNMR TAGVADRVEV RTGDLTEELD ALAEGEPFDA LTLDTGDAPA VVERADDLLA
     PGGRLAVYSP FVEGTREAAL AARDAGFDEV ETLETIQREM DFSDRGSRPS TAGVGHTGYL
     VFARAP
//