ID   M0EYJ4_9EURY            Unreviewed;       614 AA.
AC   M0EYJ4;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   27-MAR-2024, entry version 40.
DE   SubName: Full=PUA domain containing protein {ECO:0000313|EMBL:ELZ51484.1};
GN   ORFNames=C465_03780 {ECO:0000313|EMBL:ELZ51484.1};
OS   Halorubrum distributum JCM 9100.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC   Halorubraceae; Halorubrum; Halorubrum distributum group.
OX   NCBI_TaxID=1227467 {ECO:0000313|EMBL:ELZ51484.1, ECO:0000313|Proteomes:UP000011526};
RN   [1] {ECO:0000313|EMBL:ELZ51484.1, ECO:0000313|Proteomes:UP000011526}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 9100 {ECO:0000313|EMBL:ELZ51484.1,
RC   ECO:0000313|Proteomes:UP000011526};
RX   PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA   Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA   Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT   "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT   strategies for static and dynamic osmo-response.";
RL   PLoS Genet. 10:E1004784-E1004784(2014).
CC   -!- PATHWAY: tRNA modification; archaeosine-tRNA biosynthesis.
CC       {ECO:0000256|ARBA:ARBA00005030}.
CC   -!- SIMILARITY: Belongs to the archaeosine synthase type 1 family.
CC       {ECO:0000256|ARBA:ARBA00008906}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ELZ51484.1}.
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DR   EMBL; AOJM01000032; ELZ51484.1; -; Genomic_DNA.
DR   RefSeq; WP_004595907.1; NZ_AOJM01000032.1.
DR   AlphaFoldDB; M0EYJ4; -.
DR   PATRIC; fig|1227467.4.peg.701; -.
DR   UniPathway; UPA00393; -.
DR   Proteomes; UP000011526; Unassembled WGS sequence.
DR   GO; GO:0016763; F:pentosyltransferase activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0006400; P:tRNA modification; IEA:InterPro.
DR   CDD; cd21149; PUA_archaeosine_TGT; 1.
DR   Gene3D; 3.10.450.90; ArcTGT, C2 domain; 1.
DR   Gene3D; 2.30.130.10; PUA domain; 1.
DR   Gene3D; 3.20.20.105; Queuine tRNA-ribosyltransferase-like; 1.
DR   Gene3D; 3.40.50.10630; Uracil-DNA glycosylase-like; 1.
DR   InterPro; IPR040777; DUF5591.
DR   InterPro; IPR002478; PUA.
DR   InterPro; IPR015947; PUA-like_sf.
DR   InterPro; IPR036974; PUA_sf.
DR   InterPro; IPR036511; TGT-like_sf.
DR   InterPro; IPR029402; TGT_C2.
DR   InterPro; IPR038250; TGT_C2_sf.
DR   InterPro; IPR002616; tRNA_ribo_trans-like.
DR   InterPro; IPR004521; Uncharacterised_CHP00451.
DR   InterPro; IPR036895; Uracil-DNA_glycosylase-like_sf.
DR   NCBIfam; NF040592; tRNA_mod_ArcS; 1.
DR   NCBIfam; TIGR00451; unchar_dom_2; 1.
DR   PANTHER; PTHR46499:SF2; ARCHAEOSINE SYNTHASE; 1.
DR   PANTHER; PTHR46499; QUEUINE TRNA-RIBOSYLTRANSFERASE; 1.
DR   Pfam; PF17884; DUF5591; 1.
DR   Pfam; PF01472; PUA; 1.
DR   Pfam; PF01702; TGT; 1.
DR   Pfam; PF14810; TGT_C2; 1.
DR   SMART; SM00359; PUA; 1.
DR   SUPFAM; SSF88697; PUA domain-like; 1.
DR   SUPFAM; SSF51713; tRNA-guanine transglycosylase; 1.
DR   SUPFAM; SSF52141; Uracil-DNA glycosylase-like; 1.
DR   PROSITE; PS50890; PUA; 1.
PE   3: Inferred from homology;
KW   tRNA processing {ECO:0000256|ARBA:ARBA00022694}.
FT   DOMAIN          546..613
FT                   /note="PUA"
FT                   /evidence="ECO:0000259|SMART:SM00359"
SQ   SEQUENCE   614 AA;  67171 MW;  6A4541214D65082F CRC64;
     MTDYFEVHER DGAARLGAVR LADPVTTPAL ADPFLDDAGS LWAGDREVPE GDESALTVLP
     HRSFPAGTRD EVRESFAVEH PDAEFPSAAV VDSRSARDLG ADAYLLSDAQ GFVGHGEAFR
     DAIVRAKESL PPDAALGLSG VATPRNVAVL AYAGVDLVDE TLARTKGTQG MYLTADAAHF
     LEDLDELPCA CPACAKSRSE FTRADCADHN ANALRAELRR VRERIRSGRL RDYIEAQARH
     EGWLTAAFRE FDDQWGYVEE RTPLMRDAEV TAASAETLDR VEIRRFADRV TSRYRNRFTD
     QPLVLVPCSA TKPYSDSQSH RQFHDAIQWR GHTVSMTSPI GVVPQELETT YPAQHYDSVV
     TGDWSEDEIG FVAEVLRRYL ERNDYSRVIA HVPEDGYREI CERVEGDPAV DVDFEYTCVD
     HPTTDESLGE LNAALQGEPA YSKREREHNT VRAIADYLLG DGAGDDLFGG RGAGGGDGVD
     IERYGGEADV RTTGRYPKLQ VWADDPDAGR EGEPGEQLAT MVPQYGTLSF TLAGARRWVE
     SDAPTKRVEI DEFVPRGSVL APGVVDAADE IRVGDEVVIE GPKAFAVGRA AMSGPEMAGA
     TRGVAVEVRH ADEK
//