ID   M0EYM1_9EURY            Unreviewed;       488 AA.
AC   M0EYM1;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   SubName: Full=Methyltransferase type 12 {ECO:0000313|EMBL:ELZ52830.1};
GN   ORFNames=C466_09732 {ECO:0000313|EMBL:ELZ52830.1};
OS   Halorubrum distributum JCM 10118.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC   Halorubraceae; Halorubrum; Halorubrum distributum group.
OX   NCBI_TaxID=1227468 {ECO:0000313|EMBL:ELZ52830.1, ECO:0000313|Proteomes:UP000011614};
RN   [1] {ECO:0000313|Proteomes:UP000011614}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 10118 {ECO:0000313|Proteomes:UP000011614};
RA   Becker E.A., Seitzer P., Tritt A., Larsen D., Yao A., Wu D., Darling A.,
RA   Eisen J.A., Facciotti M.T.;
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ELZ52830.1, ECO:0000313|Proteomes:UP000011614}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 10118 {ECO:0000313|EMBL:ELZ52830.1,
RC   ECO:0000313|Proteomes:UP000011614};
RX   PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA   Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA   Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT   "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT   strategies for static and dynamic osmo-response.";
RL   PLoS Genet. 10:E1004784-E1004784(2014).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ELZ52830.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AOJN01000049; ELZ52830.1; -; Genomic_DNA.
DR   RefSeq; WP_004598176.1; NZ_AOJN01000049.1.
DR   AlphaFoldDB; M0EYM1; -.
DR   PATRIC; fig|1227468.4.peg.1904; -.
DR   OrthoDB; 117536at2157; -.
DR   Proteomes; UP000011614; Unassembled WGS sequence.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0044249; P:cellular biosynthetic process; IEA:UniProt.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; IEA:UniProt.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   GO; GO:1901576; P:organic substance biosynthetic process; IEA:UniProt.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR013217; Methyltransf_12.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF08242; Methyltransf_12; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000313|EMBL:ELZ52830.1};
KW   Transferase {ECO:0000313|EMBL:ELZ52830.1}.
FT   DOMAIN          165..274
FT                   /note="Methyltransferase type 12"
FT                   /evidence="ECO:0000259|Pfam:PF08242"
SQ   SEQUENCE   488 AA;  53600 MW;  A38E97ADE12DFF66 CRC64;
     MIDRTAVRNN ANYLRNVRPI DPEEIAEYIE GTPHPAVVRE TLREEAFDLR LREREDGAFV
     PVEESPVDPP GWAPEALPEA YAFAVEDLLV REYGANWHRG ESGDELRERV RRLKTDYLYE
     NEVEYDHVAA LGYAIYHLPA YYATVGYVLD DLTENGLIDR TLRVLDVGAG VGGPALGLHD
     YLPDDAVVDY HAVEPSAATD VLDRLLEETG RNFRTTVHEA TAEAFLGLDE GEEADPATDD
     PFDLVLFGNV LSELADPVAV ADAALDALAP DGSLVAFAPA DRNTAIGLRR VERALVAGDG
     DGAGPGRDAE IYSPALRLWP DAIPSDPGWS FDVAADLAVP PFQRRLDEAT ARGETDEPGE
     FVNVDVQFAY SILRRDGKRR VDVEASAERC ARMAESERHV TDRVNLLAVK LSHDLSEGDN
     ALYRVGDGSQ ATDHYLVCTR ETALNRDLRE AGYGSVVFVE NGLVLWNEDE GAYNVVVDDE
     TVVDLVAP
//