ID M0F144_9EURY Unreviewed; 493 AA.
AC M0F144;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=dTDP-4-dehydrorhamnose reductase {ECO:0000313|EMBL:ELZ53038.1};
GN ORFNames=C466_10782 {ECO:0000313|EMBL:ELZ53038.1};
OS Halorubrum distributum JCM 10118.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Halorubraceae; Halorubrum; Halorubrum distributum group.
OX NCBI_TaxID=1227468 {ECO:0000313|EMBL:ELZ53038.1, ECO:0000313|Proteomes:UP000011614};
RN [1] {ECO:0000313|Proteomes:UP000011614}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 10118 {ECO:0000313|Proteomes:UP000011614};
RA Becker E.A., Seitzer P., Tritt A., Larsen D., Yao A., Wu D., Darling A.,
RA Eisen J.A., Facciotti M.T.;
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ELZ53038.1, ECO:0000313|Proteomes:UP000011614}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 10118 {ECO:0000313|EMBL:ELZ53038.1,
RC ECO:0000313|Proteomes:UP000011614};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELZ53038.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AOJN01000049; ELZ53038.1; -; Genomic_DNA.
DR RefSeq; WP_004596118.1; NZ_AOJN01000049.1.
DR AlphaFoldDB; M0F144; -.
DR PATRIC; fig|1227468.4.peg.2120; -.
DR OrthoDB; 4907at2157; -.
DR Proteomes; UP000011614; Unassembled WGS sequence.
DR CDD; cd05254; dTDP_HR_like_SDR_e; 1.
DR CDD; cd06223; PRTases_typeI; 1.
DR Gene3D; 3.40.50.2020; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR005913; dTDP_dehydrorham_reduct.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR000836; PRibTrfase_dom.
DR InterPro; IPR029057; PRTase-like.
DR InterPro; IPR029903; RmlD-like-bd.
DR PANTHER; PTHR10491; DTDP-4-DEHYDRORHAMNOSE REDUCTASE; 1.
DR PANTHER; PTHR10491:SF4; METHIONINE ADENOSYLTRANSFERASE 2 SUBUNIT BETA; 1.
DR Pfam; PF00156; Pribosyltran; 1.
DR Pfam; PF04321; RmlD_sub_bind; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF53271; PRTase-like; 1.
PE 4: Predicted;
FT DOMAIN 4..257
FT /note="RmlD-like substrate binding"
FT /evidence="ECO:0000259|Pfam:PF04321"
FT DOMAIN 317..412
FT /note="Phosphoribosyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00156"
SQ SEQUENCE 493 AA; 55237 MW; F6C8A546EED9B636 CRC64;
MTKRILIVGK SGLLGTKLHE RLVNKYRVGG VSKSGAGMNN RELDITEQDA VETFFDTYSF
DVVIHVAANT DVDFCEHNQT EAWETNVEGT KNLVLECKKR GIKFCYLSSD YIFSGANPPY
EADANPDPVN YYGMTKLEGE RIIREELHDF VIIRPGKLYG YTPDFGCDPF TSWVRNSLSE
DSTVRVDDSI VKYPTLIDDV SRFVEAAIES DWTGLFNFSG PDSTTKYEWA RSIAANYGFD
SSRVEAKTAD PYADRPQDVR YVSTDFGIDP HGVETGIEVM YKQEYCSFRP IYRMDIAEEF
QGQSSGEIRK RLGAVLARED DIEPDVVVPI PKSGIYPAIG YAEEIGSPLE FALSKQQLRK
RTLYDESIDR INVLEEKMRA IKSLIENKTV AVVDEAVLSG KTLRTVIPIL GAASKIHVRI
SSPPVTQTCP AYMHPENSNI FVDDLDIDSE SNDIESAIAA ELNVSSVKYV DRDSYLLEMG
VEGDDICSFC FHS
//
