ID M0IK45_9EURY Unreviewed; 258 AA.
AC M0IK45;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=4-hydroxy-2-oxovalerate aldolase {ECO:0000313|EMBL:ELZ96412.1};
GN ORFNames=C441_06214 {ECO:0000313|EMBL:ELZ96412.1};
OS Haloferax sulfurifontis ATCC BAA-897.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Haloferacaceae; Haloferax.
OX NCBI_TaxID=662480 {ECO:0000313|EMBL:ELZ96412.1, ECO:0000313|Proteomes:UP000011508};
RN [1] {ECO:0000313|EMBL:ELZ96412.1, ECO:0000313|Proteomes:UP000011508}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-897 {ECO:0000313|EMBL:ELZ96412.1,
RC ECO:0000313|Proteomes:UP000011508};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
CC -!- SIMILARITY: Belongs to the HpcH/HpaI aldolase family.
CC {ECO:0000256|ARBA:ARBA00005568}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELZ96412.1}.
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DR EMBL; AOLM01000008; ELZ96412.1; -; Genomic_DNA.
DR RefSeq; WP_007274312.1; NZ_AOLM01000008.1.
DR AlphaFoldDB; M0IK45; -.
DR PATRIC; fig|662480.6.peg.1226; -.
DR OrthoDB; 142679at2157; -.
DR Proteomes; UP000011508; Unassembled WGS sequence.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.20.20.60; Phosphoenolpyruvate-binding domains; 1.
DR InterPro; IPR005000; Aldolase/citrate-lyase_domain.
DR InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR InterPro; IPR040442; Pyrv_Kinase-like_dom_sf.
DR PANTHER; PTHR30502; 2-KETO-3-DEOXY-L-RHAMNONATE ALDOLASE; 1.
DR PANTHER; PTHR30502:SF0; PHOSPHOENOLPYRUVATE CARBOXYLASE FAMILY PROTEIN; 1.
DR Pfam; PF03328; HpcH_HpaI; 1.
DR SUPFAM; SSF51621; Phosphoenolpyruvate/pyruvate domain; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|ARBA:ARBA00023239}.
FT DOMAIN 18..242
FT /note="HpcH/HpaI aldolase/citrate lyase"
FT /evidence="ECO:0000259|Pfam:PF03328"
SQ SEQUENCE 258 AA; 27245 MW; F7F33C791CAECB6B CRC64;
MVEHDGLKRA GQSPDQLIGT WAVIPHPSTA ELLAGVGYDF VVLDAEHTPM SYETMENMVR
AVDAAPGETE TLVRVPDDDP ATLKRTLDLD PTGVLVPMVE TAEQAAAVVD ASRYPPTGTR
GLGLGRATGY GRALGEHVES AEETVVRYVQ LESERAVANA EAIAAVDGID GVFIGPVDLS
MSMDRFGEWD DGDFLEAVDR VVEAASNAGV AVGTLATDAD QRATRLDWGV DYLVAGVDAL
HLSDGAVEAL DHSTTLSE
//
