ID   M0JZU7_9EURY            Unreviewed;       303 AA.
AC   M0JZU7;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   SubName: Full=Cysteine synthase {ECO:0000313|EMBL:EMA14023.1, ECO:0000313|EMBL:QUJ72977.1};
GN   ORFNames=C436_07717 {ECO:0000313|EMBL:EMA14023.1}, KDQ40_04295
GN   {ECO:0000313|EMBL:QUJ72977.1};
OS   Haloarcula sinaiiensis ATCC 33800.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Haloarculaceae; Haloarcula.
OX   NCBI_TaxID=662476 {ECO:0000313|EMBL:EMA14023.1, ECO:0000313|Proteomes:UP000011659};
RN   [1] {ECO:0000313|EMBL:EMA14023.1, ECO:0000313|Proteomes:UP000011659}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33800 {ECO:0000313|EMBL:EMA14023.1,
RC   ECO:0000313|Proteomes:UP000011659};
RX   PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA   Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA   Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT   "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT   strategies for static and dynamic osmo-response.";
RL   PLoS Genet. 10:E1004784-E1004784(2014).
RN   [2] {ECO:0000313|EMBL:QUJ72977.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ATCC 33800 {ECO:0000313|EMBL:QUJ72977.1};
RA   Fomenkov A., DasSarma P., DasSarma S., Roberts R.J.;
RT   "Complete Genome sequence and Methylome Analysis of the Haloarchaeon
RT   Haloarcula sinaiiensis.";
RL   Submitted (APR-2021) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
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DR   EMBL; AOLR01000015; EMA14023.1; -; Genomic_DNA.
DR   EMBL; CP073366; QUJ72977.1; -; Genomic_DNA.
DR   RefSeq; WP_004960667.1; NZ_CP073366.1.
DR   AlphaFoldDB; M0JZU7; -.
DR   GeneID; 64822149; -.
DR   KEGG; hsin:KDQ40_04295; -.
DR   PATRIC; fig|662476.7.peg.1533; -.
DR   OrthoDB; 10138at2157; -.
DR   Proteomes; UP000011659; Unassembled WGS sequence.
DR   Proteomes; UP000682967; Chromosome.
DR   GO; GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.
DR   CDD; cd01561; CBS_like; 1.
DR   Gene3D; 3.40.50.1100; -; 2.
DR   InterPro; IPR001216; P-phosphate_BS.
DR   InterPro; IPR001926; TrpB-like_PALP.
DR   InterPro; IPR036052; TrpB-like_PALP_sf.
DR   PANTHER; PTHR10314; CYSTATHIONINE BETA-SYNTHASE; 1.
DR   PANTHER; PTHR10314:SF194; CYSTATHIONINE BETA-SYNTHASE; 1.
DR   Pfam; PF00291; PALP; 1.
DR   SUPFAM; SSF53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes; 1.
DR   PROSITE; PS00901; CYS_SYNTHASE; 1.
PE   4: Predicted;
FT   DOMAIN          11..275
FT                   /note="Tryptophan synthase beta chain-like PALP"
FT                   /evidence="ECO:0000259|Pfam:PF00291"
SQ   SEQUENCE   303 AA;  32374 MW;  17D17C5578F0BFBD CRC64;
     MKDSILDTIG SPLVSVRAPE GATVAAKIES FNPGGSAKDR PAKYMIDDAE RNGSLQPDDT
     LVEPTSGNTG IGMAMVGATK GYDVVLVMPS SKSPERRQIM KAYGAEIELV EGDISDAKER
     ANELCERDDY VQLRQFENPA NPTAHYETTG EEILEQVGDR TVDALVAGVG TGGTLTGTGR
     RLRDAFPGMD IVAVEPADNA VLSGMEPGTG EDSFQGMGPG FISDNLDTDL LDDVMTVELP
     DAEDECRRLA HEEGILVGQS SGASNLAARE FAEQLIRDGV DDPLVVTVYW DSGERYMSTG
     MFD
//