ID M0JZW4_9EURY Unreviewed; 630 AA.
AC M0JZW4;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 24-JAN-2024, entry version 43.
DE SubName: Full=MCP domain-containing signal transducer {ECO:0000313|EMBL:EMA13454.1};
DE SubName: Full=Methyl-accepting chemotaxis protein {ECO:0000313|EMBL:QUJ73190.1};
GN ORFNames=C436_08811 {ECO:0000313|EMBL:EMA13454.1}, KDQ40_05425
GN {ECO:0000313|EMBL:QUJ73190.1};
OS Haloarcula sinaiiensis ATCC 33800.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Haloarculaceae; Haloarcula.
OX NCBI_TaxID=662476 {ECO:0000313|EMBL:EMA13454.1, ECO:0000313|Proteomes:UP000011659};
RN [1] {ECO:0000313|EMBL:EMA13454.1, ECO:0000313|Proteomes:UP000011659}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33800 {ECO:0000313|EMBL:EMA13454.1,
RC ECO:0000313|Proteomes:UP000011659};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
RN [2] {ECO:0000313|EMBL:QUJ73190.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 33800 {ECO:0000313|EMBL:QUJ73190.1};
RA Fomenkov A., DasSarma P., DasSarma S., Roberts R.J.;
RT "Complete Genome sequence and Methylome Analysis of the Haloarchaeon
RT Haloarcula sinaiiensis.";
RL Submitted (APR-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC family. {ECO:0000256|ARBA:ARBA00029447}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AOLR01000018; EMA13454.1; -; Genomic_DNA.
DR EMBL; CP073366; QUJ73190.1; -; Genomic_DNA.
DR RefSeq; WP_004961199.1; NZ_CP073366.1.
DR AlphaFoldDB; M0JZW4; -.
DR GeneID; 64822375; -.
DR KEGG; hsin:KDQ40_05425; -.
DR PATRIC; fig|662476.7.peg.1751; -.
DR OrthoDB; 8523at2157; -.
DR Proteomes; UP000011659; Unassembled WGS sequence.
DR Proteomes; UP000682967; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR GO; GO:0006935; P:chemotaxis; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd11386; MCP_signal; 1.
DR Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR InterPro; IPR004090; Chemotax_Me-accpt_rcpt.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR004089; MCPsignal_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR32089:SF92; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR Pfam; PF00015; MCPsignal; 1.
DR PRINTS; PR00260; CHEMTRNSDUCR.
DR SMART; SM00304; HAMP; 2.
DR SMART; SM00283; MA; 1.
DR SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW ProRule:PRU00284}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 47..67
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 79..102
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 109..129
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 149..166
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 186..207
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 274..320
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 339..577
FT /note="Methyl-accepting transducer"
FT /evidence="ECO:0000259|PROSITE:PS50111"
FT REGION 217..236
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 241..271
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 582..609
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 241..258
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 584..609
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 630 AA; 67839 MW; F699983EDB56366C CRC64;
MAQPTGNVGQ ETEGSPGPAE RLESFVSYIP DGSTIPDKQW RNRHRSVVLV TLLHIPFLFG
LGIYTGSTPI AEAQIPATAL PRVLLLCGVV FALSAGSLIA RFRRRVRTIL SVTAVFVSSL
ALVQLSGGYI EAHFHFFVGM AMVAVYEDWV PFLWGLAYVV LTHGYFGTID PSRVYNHAAA
INNPWAWGLI HGGFVLMLCV ALVNNWVSTE RSREKSQERF EQAEQRASEI DDLQAKQEEI
ERKRAEAKEA REKAEAKMQA AEQQNTELQE TASRFSEAMA AAADGDLTVR VDPDVADNEA
MAQIAESFNK MMTETESAME EIQTFSEEVA TTSDQVTAGA NEATGASEDM SESIQGIASG
ADEQREMLET VSDEMTDLSA TVEEVAASAE TVAERSRETA EIADAGEETA QEAIAGSREV
QTAIDSTVEN VERLDEKMAE IGDIVELIGD IAEQTNMLAL NANIEAARAG NGSGGDGFAV
VADEVKQLAE ETQTSASEIE QLIAETQAQT ETTVTEARGA KEDMQESTEA VEAVVDTFTQ
VAENAEATDN GIQEISDTTD DQAATTEETV SMVEEAVDIS EATAAETETA SATAQEQAAS
MSQVSASIES LAEQSERLQT MLSEFDVGSR
//
