ID   M0L796_9EURY            Unreviewed;       690 AA.
AC   M0L796;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   24-JAN-2024, entry version 29.
DE   SubName: Full=Serine protein kinase, PrkA {ECO:0000313|EMBL:EMA29421.1};
GN   ORFNames=C446_17202 {ECO:0000313|EMBL:EMA29421.1};
OS   Halobiforma nitratireducens JCM 10879.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC   Natrialbaceae; Halobiforma.
OX   NCBI_TaxID=1227454 {ECO:0000313|EMBL:EMA29421.1, ECO:0000313|Proteomes:UP000011607};
RN   [1] {ECO:0000313|EMBL:EMA29421.1, ECO:0000313|Proteomes:UP000011607}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 10879 {ECO:0000313|EMBL:EMA29421.1,
RC   ECO:0000313|Proteomes:UP000011607};
RX   PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA   Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA   Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT   "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT   strategies for static and dynamic osmo-response.";
RL   PLoS Genet. 10:E1004784-E1004784(2014).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EMA29421.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AOMA01000183; EMA29421.1; -; Genomic_DNA.
DR   RefSeq; WP_006674317.1; NZ_AOMA01000183.1.
DR   AlphaFoldDB; M0L796; -.
DR   STRING; 1227454.C446_17202; -.
DR   PATRIC; fig|1227454.3.peg.3521; -.
DR   eggNOG; arCOG02891; Archaea.
DR   OrthoDB; 191283at2157; -.
DR   Proteomes; UP000011607; Unassembled WGS sequence.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR013153; Prk_AAA_dom.
DR   InterPro; IPR010650; PrkA_C_dom.
DR   PANTHER; PTHR30267; PROTEIN KINASE PRKA; 1.
DR   PANTHER; PTHR30267:SF2; PROTEIN PRKA; 1.
DR   Pfam; PF08298; AAA_PrkA; 1.
DR   Pfam; PF06798; PrkA; 1.
DR   SMART; SM00763; AAA_PrkA; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000313|EMBL:EMA29421.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000011607};
KW   Transferase {ECO:0000313|EMBL:EMA29421.1}.
FT   DOMAIN          27..421
FT                   /note="PrkA AAA"
FT                   /evidence="ECO:0000259|SMART:SM00763"
SQ   SEQUENCE   690 AA;  80298 MW;  0D3B337D95AFFF7C CRC64;
     MTGDIETLEE LSTEYKESMP ADLRETKSFD WYLEEVYEDP KVARNAHQRV ADMFDYYGTT
     YDETEGVVEY QLASEDPLND GENTFYGRVI HQSIHEFVNK VKSGARRLGP ERRIKLLLGP
     VGSGKSHFDK QVRQYFEDYT MREEGRMYTF EWTNLCDVVQ DQDPADDTVR SPMNQDPLVL
     LPLAQRQQVI DDLNERLDAP YTIQNEQALD PESEFYMDKL LAYYDDDLKQ VLENHVEIVR
     LVADENKRQA LETFEPKDKK NQDETELTGD VNYSKIAIYG ESDPRAFDYS GAFCNANRGV
     FSGEELLKLQ REFLYDFLHA TQEQTIKPKN NPRIDIDQVI VGRTNMPEYK DKKGDEKMEA
     FNDRTKRIDF PYVLSYEDEA EIYRKMLNNA DVPDINVEPH TLEMAGLFGV LTRVEEPDAE
     TVDLLSKAKA YNGEIDEGDD IDVKKLREEA EQKAEIGEGM VGISPRFIGD EIAEAIMDSK
     HRSRGFLSPL TVFNFFEENL EHHGSIPEDQ FQTYYRYLET VREEYKERAI EDVRHALAYD
     VDEIQRQGEK YMDHVMAYID DDTIEDELTG REQEPDETFL RSVEEKLDIP EDRKDDFRQE
     VSNWVSRRAR EGEAFNPQDN ERLRRALERK LWEDKKHNIN FSALVSANEF DDDERSSWID
     ALIEQGYSEG GAKEVLEFAG AEVAKAEIEE
//