ID   M0LZW8_9EURY            Unreviewed;       568 AA.
AC   M0LZW8;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   24-JAN-2024, entry version 36.
DE   RecName: Full=Helicase HerA central domain-containing protein {ECO:0000259|Pfam:PF01935};
GN   ORFNames=C447_10775 {ECO:0000313|EMBL:EMA37914.1};
OS   Halococcus hamelinensis 100A6.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Halococcaceae; Halococcus.
OX   NCBI_TaxID=1132509 {ECO:0000313|EMBL:EMA37914.1, ECO:0000313|Proteomes:UP000011566};
RN   [1] {ECO:0000313|EMBL:EMA37914.1, ECO:0000313|Proteomes:UP000011566}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=100A6 {ECO:0000313|EMBL:EMA37914.1,
RC   ECO:0000313|Proteomes:UP000011566};
RX   PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA   Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA   Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT   "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT   strategies for static and dynamic osmo-response.";
RL   PLoS Genet. 10:E1004784-E1004784(2014).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EMA37914.1}.
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DR   EMBL; AOMB01000032; EMA37914.1; -; Genomic_DNA.
DR   RefSeq; WP_007693735.1; NZ_AOMB01000032.1.
DR   AlphaFoldDB; M0LZW8; -.
DR   PATRIC; fig|1132509.6.peg.2435; -.
DR   eggNOG; arCOG06224; Archaea.
DR   OrthoDB; 242625at2157; -.
DR   Proteomes; UP000011566; Unassembled WGS sequence.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR002789; HerA_central.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR42957; HELICASE MJ1565-RELATED; 1.
DR   PANTHER; PTHR42957:SF1; HELICASE MJ1565-RELATED; 1.
DR   Pfam; PF01935; DUF87; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000011566}.
FT   DOMAIN          29..75
FT                   /note="Helicase HerA central"
FT                   /evidence="ECO:0000259|Pfam:PF01935"
FT   REGION          334..458
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          282..330
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        348..362
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        375..400
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   568 AA;  60903 MW;  49F230C0C6028864 CRC64;
     MASEDAETVT LDAAGEVRIP TIELLTGRGF VTGKSGGGKS NTASVVAEEL LDDGHPLMIV
     DTDGEYYGLK ERYEVLHAGA DDECDVQVGT EHADKLAELA LDGGVPVILD VSAYLDDGGH
     DIVRATVEAL FRREQEARRP FLLLVEEVHE FIPESGGLTE AGKMLVRVAK RGRKRGLGFC
     GISQRPANVK KDVITQCDWL CWHRLTWNND TAVVGRVLDN QAAEAVQNLA DGEAILVTDW
     DGTRRRVQVR RKRTFDAGST PGLGDVDRPE LKSIGEGLLG DLTEISDQKR EHENRLAKLE
     ADLESKNERI AELERELSRA RDLSEMAEQF TRALTGDAVS SASQRTRSAD DPTHHELGDF
     EATDEGADGD GTADTPTDDA STGDATSSDN TDTAATTDIA GTVDADNALD TDEGSEDPAT
     DEAAGEPSSE AGEADPIRVA DDPGGPGGSN PDPADGRSYA DLLDMDVVRH EVQQAEDHSR
     ASPTYAKGII ATLIDEGGPV SQRTLLSRVG GSSTDEVTTM ATTLEAMRTV EKEHTDEGLM
     IGIDPDGVRE LRETSLGRER TRSLADGF
//