ID   M0M949_9EURY            Unreviewed;       388 AA.
AC   M0M949;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   24-JAN-2024, entry version 35.
DE   SubName: Full=Nicotinate phosphoribosyltransferase {ECO:0000313|EMBL:EMA41868.1};
DE            EC=6.3.4.21 {ECO:0000313|EMBL:EMA41868.1};
GN   ORFNames=C446_04645 {ECO:0000313|EMBL:EMA41868.1};
OS   Halobiforma nitratireducens JCM 10879.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC   Natrialbaceae; Halobiforma.
OX   NCBI_TaxID=1227454 {ECO:0000313|EMBL:EMA41868.1, ECO:0000313|Proteomes:UP000011607};
RN   [1] {ECO:0000313|EMBL:EMA41868.1, ECO:0000313|Proteomes:UP000011607}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 10879 {ECO:0000313|EMBL:EMA41868.1,
RC   ECO:0000313|Proteomes:UP000011607};
RX   PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA   Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA   Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT   "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT   strategies for static and dynamic osmo-response.";
RL   PLoS Genet. 10:E1004784-E1004784(2014).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EMA41868.1}.
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DR   EMBL; AOMA01000062; EMA41868.1; -; Genomic_DNA.
DR   RefSeq; WP_006671886.1; NZ_AOMA01000062.1.
DR   AlphaFoldDB; M0M949; -.
DR   STRING; 1227454.C446_04645; -.
DR   PATRIC; fig|1227454.3.peg.912; -.
DR   eggNOG; arCOG01481; Archaea.
DR   OrthoDB; 371831at2157; -.
DR   Proteomes; UP000011607; Unassembled WGS sequence.
DR   GO; GO:0004516; F:nicotinate phosphoribosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004514; F:nicotinate-nucleotide diphosphorylase (carboxylating) activity; IEA:InterPro.
DR   GO; GO:0009435; P:NAD biosynthetic process; IEA:InterPro.
DR   CDD; cd01571; NAPRTase_B; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   Gene3D; 3.90.1170.20; Quinolinate phosphoribosyl transferase, N-terminal domain; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR035809; NAPRTase_arc-type.
DR   InterPro; IPR036068; Nicotinate_pribotase-like_C.
DR   InterPro; IPR037128; Quinolinate_PRibosylTase_N_sf.
DR   InterPro; IPR002638; Quinolinate_PRibosylTrfase_C.
DR   PANTHER; PTHR43202:SF1; NICOTINATE PHOSPHORIBOSYLTRANSFERASE; 1.
DR   PANTHER; PTHR43202; NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE; 1.
DR   Pfam; PF01729; QRPTase_C; 1.
DR   SUPFAM; SSF51690; Nicotinate/Quinolinate PRTase C-terminal domain-like; 1.
DR   SUPFAM; SSF54675; Nicotinate/Quinolinate PRTase N-terminal domain-like; 1.
PE   4: Predicted;
KW   Glycosyltransferase {ECO:0000313|EMBL:EMA41868.1};
KW   Ligase {ECO:0000313|EMBL:EMA41868.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000011607};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:EMA41868.1}.
FT   DOMAIN          115..304
FT                   /note="Quinolinate phosphoribosyl transferase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF01729"
SQ   SEQUENCE   388 AA;  41650 MW;  DB3D9A4C061E216B CRC64;
     MSNPFGTVPT EAILEGDATD AYFERTRTTL ETAGKNPHVV AEVTADQFPT GEFDVLTGVK
     DVATLFEGRR VDVDAMPDGQ LFDGGPVLRI EGPYLEFAEL ETSLLGFLSQ PSGFATAALE
     ARRAAPKSLV LSFGARHVHP SIAAVVERAA LLAGLDGFSH VAAGDVLGRE AGGTMPHALL
     FCFGEGNQPD AWDAFDEAVP EDVPRIALAD TFWDEVSESL LAADTLGDRL DGVRIDTTSS
     RRGDFRHIIR EVRWELDAHG YEDIDIFCSG GIDPDAIRTL RDVADGFGVG SHVTSAPSVD
     FSLDIVEIAG EPISKRGKLS GVKEVYRTPD GGHHVALANR DDPEDGESLL EPLVRDGEVV
     REFDLEAASE RCLADAESVG FRSDKNAE
//