ID M0NE50_9EURY Unreviewed; 226 AA.
AC M0NE50;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=TetR family transcriptional regulator {ECO:0000313|EMBL:EMA56262.1};
GN ORFNames=C451_03339 {ECO:0000313|EMBL:EMA56262.1};
OS Halococcus thailandensis JCM 13552.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Halococcaceae; Halococcus.
OX NCBI_TaxID=1227457 {ECO:0000313|EMBL:EMA56262.1, ECO:0000313|Proteomes:UP000011680};
RN [1] {ECO:0000313|EMBL:EMA56262.1, ECO:0000313|Proteomes:UP000011680}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 13552 {ECO:0000313|EMBL:EMA56262.1,
RC ECO:0000313|Proteomes:UP000011680};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMA56262.1}.
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DR EMBL; AOMF01000075; EMA56262.1; -; Genomic_DNA.
DR AlphaFoldDB; M0NE50; -.
DR PATRIC; fig|1227457.3.peg.593; -.
DR eggNOG; arCOG02646; Archaea.
DR Proteomes; UP000011680; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 1.
DR InterPro; IPR039538; BetI_C.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001647; HTH_TetR.
DR InterPro; IPR036271; Tet_transcr_reg_TetR-rel_C_sf.
DR PANTHER; PTHR47506:SF1; HTH-TYPE TRANSCRIPTIONAL REGULATOR YJDC; 1.
DR PANTHER; PTHR47506; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF13977; TetR_C_6; 1.
DR Pfam; PF00440; TetR_N; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF48498; Tetracyclin repressor-like, C-terminal domain; 1.
DR PROSITE; PS50977; HTH_TETR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00335}; Repressor {ECO:0000256|ARBA:ARBA00022491}.
FT DOMAIN 26..86
FT /note="HTH tetR-type"
FT /evidence="ECO:0000259|PROSITE:PS50977"
FT DNA_BIND 49..68
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 226 AA; 25602 MW; C714DD477CC51F76 CRC64;
MQSGIEMSTD EDDGSDQAGD TETFDCDARK AIMEATYRAL CAHGAADLSV QDIADKFEKS
KSLIFYHYDS KEELLTSFLV YLLDGFEKRV ATTDDKEPIE QLDTLIDALL FGPEDHEEFQ
TAMLELRSKA PYNEAYREQF RTNSEYIHGL FEAVIERGIE REEFADVDPS RIATMLLTTI
DGARTRFVVH GDEESLDAAR EVIDDQLDRT LFAGIESERL SGTRMP
//
