ID   M0P9S2_9EURY            Unreviewed;       600 AA.
AC   M0P9S2;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   SubName: Full=PUA domain containing protein {ECO:0000313|EMBL:EMA66786.1};
GN   ORFNames=C461_09756 {ECO:0000313|EMBL:EMA66786.1};
OS   Halorubrum aidingense JCM 13560.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC   Halorubraceae; Halorubrum.
OX   NCBI_TaxID=1230454 {ECO:0000313|EMBL:EMA66786.1, ECO:0000313|Proteomes:UP000011575};
RN   [1] {ECO:0000313|EMBL:EMA66786.1, ECO:0000313|Proteomes:UP000011575}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 13560 {ECO:0000313|EMBL:EMA66786.1,
RC   ECO:0000313|Proteomes:UP000011575};
RX   PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA   Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA   Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT   "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT   strategies for static and dynamic osmo-response.";
RL   PLoS Genet. 10:E1004784-E1004784(2014).
CC   -!- PATHWAY: tRNA modification; archaeosine-tRNA biosynthesis.
CC       {ECO:0000256|ARBA:ARBA00005030}.
CC   -!- SIMILARITY: Belongs to the archaeosine synthase type 1 family.
CC       {ECO:0000256|ARBA:ARBA00008906}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EMA66786.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AOJI01000025; EMA66786.1; -; Genomic_DNA.
DR   RefSeq; WP_008000762.1; NZ_AOJI01000025.1.
DR   AlphaFoldDB; M0P9S2; -.
DR   STRING; 1230454.C461_09756; -.
DR   PATRIC; fig|1230454.4.peg.1965; -.
DR   OrthoDB; 115061at2157; -.
DR   UniPathway; UPA00393; -.
DR   Proteomes; UP000011575; Unassembled WGS sequence.
DR   GO; GO:0016763; F:pentosyltransferase activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0006400; P:tRNA modification; IEA:InterPro.
DR   CDD; cd21149; PUA_archaeosine_TGT; 1.
DR   Gene3D; 3.10.450.90; ArcTGT, C2 domain; 1.
DR   Gene3D; 2.30.130.10; PUA domain; 1.
DR   Gene3D; 3.20.20.105; Queuine tRNA-ribosyltransferase-like; 1.
DR   Gene3D; 3.40.50.10630; Uracil-DNA glycosylase-like; 1.
DR   InterPro; IPR040777; DUF5591.
DR   InterPro; IPR002478; PUA.
DR   InterPro; IPR015947; PUA-like_sf.
DR   InterPro; IPR036974; PUA_sf.
DR   InterPro; IPR036511; TGT-like_sf.
DR   InterPro; IPR029402; TGT_C2.
DR   InterPro; IPR038250; TGT_C2_sf.
DR   InterPro; IPR002616; tRNA_ribo_trans-like.
DR   InterPro; IPR004521; Uncharacterised_CHP00451.
DR   InterPro; IPR036895; Uracil-DNA_glycosylase-like_sf.
DR   NCBIfam; NF040592; tRNA_mod_ArcS; 1.
DR   NCBIfam; TIGR00451; unchar_dom_2; 1.
DR   PANTHER; PTHR46499:SF2; ARCHAEOSINE SYNTHASE; 1.
DR   PANTHER; PTHR46499; QUEUINE TRNA-RIBOSYLTRANSFERASE; 1.
DR   Pfam; PF17884; DUF5591; 1.
DR   Pfam; PF01472; PUA; 1.
DR   Pfam; PF01702; TGT; 1.
DR   Pfam; PF14810; TGT_C2; 1.
DR   SMART; SM00359; PUA; 1.
DR   SUPFAM; SSF88802; Pre-PUA domain; 1.
DR   SUPFAM; SSF88697; PUA domain-like; 1.
DR   SUPFAM; SSF51713; tRNA-guanine transglycosylase; 1.
DR   SUPFAM; SSF52141; Uracil-DNA glycosylase-like; 1.
DR   PROSITE; PS50890; PUA; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   tRNA processing {ECO:0000256|ARBA:ARBA00022694}.
FT   DOMAIN          532..599
FT                   /note="PUA"
FT                   /evidence="ECO:0000259|SMART:SM00359"
FT   COILED          204..231
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   600 AA;  65871 MW;  C53CB84D022C023C CRC64;
     MTDYFEVHER DGAARLGELR LADPVTTPAL ADPFLEDAGS LWAGDRTVPD GDEDSLTVLP
     HRSFPAGTRE EVRESFAVDH PDVDFPAAAV VDSAGARDAG VDAYVLSDAQ GFVGHGEAFR
     DAIVSAKAAL PADTALVLSG VATPLNVALL AYAGVDLVDA TLARTKGTQG MYLTADAEHF
     LEDLDELPCA CPACAQPRDE FTRADCAEHN VNALRAELRR VRERIRSGRL RDYIEGQTRH
     EQWLTAAFRE FDDQWAYVEE RTPLMRDAEV TAATAETLDR VEIQRFADRV TSRYTNRFTD
     QPLVLVPCSA TKPYSDSQSH RQFHDAIQWR GHTVSMTSPI GVVPQELETT YPAQHYDAVV
     TGDWSEDEIG FVAEVLRRYL ERNDYSRVIA HVPEDGYREI CERVEADPAI DVPFEYTCVD
     HPTTDESLGE LNAALQGEPA YSKREREHNT VRAIADYLLG DGAGDDLFGG PGEADVRTTG
     RYPKLQVWAD DPDAGREGEP GEQLATMVPQ YGTLSFTIEG ARHWVESDAP TKRVEIDAFV
     PHGSVLAPGV VDADDDIRVG DEVVIEGPSA FAIGRAQMSG PEMVDSTRGV ASEVRHVDEK
//