ID M0PE04_9EURY Unreviewed; 780 AA.
AC M0PE04;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=DEAD/DEAH box helicase {ECO:0000313|EMBL:EMA67040.1};
GN ORFNames=C468_03243 {ECO:0000313|EMBL:EMA67040.1};
OS Halorubrum kocurii JCM 14978.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Halorubraceae; Halorubrum.
OX NCBI_TaxID=1230456 {ECO:0000313|EMBL:EMA67040.1, ECO:0000313|Proteomes:UP000011546};
RN [1] {ECO:0000313|EMBL:EMA67040.1, ECO:0000313|Proteomes:UP000011546}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 14978 {ECO:0000313|EMBL:EMA67040.1,
RC ECO:0000313|Proteomes:UP000011546};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMA67040.1}.
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DR EMBL; AOJH01000027; EMA67040.1; -; Genomic_DNA.
DR RefSeq; WP_008847408.1; NZ_AOJH01000027.1.
DR AlphaFoldDB; M0PE04; -.
DR STRING; 1230456.C468_03243; -.
DR PATRIC; fig|1230456.3.peg.620; -.
DR OrthoDB; 371946at2157; -.
DR Proteomes; UP000011546; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd18795; SF2_C_Ski2; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.10.3380.10; Sec63 N-terminal domain-like domain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004179; Sec63-dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR47961; DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED; 1.
DR PANTHER; PTHR47961:SF6; DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF14520; HHH_5; 1.
DR Pfam; PF02889; Sec63; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00973; Sec63; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF158702; Sec63 N-terminal domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:EMA67040.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 28..197
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 232..424
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 780 AA; 85690 MW; 903A4A84E7D9F4BA CRC64;
MKVADAVPEF ADAFGFEEFN RMQREALPGI LETDHNVVAS APTASGKTAL AELAICKTLS
EGGTALFVAP LRALTNEKES EWERFEELGY SVYVVSGERD LNPRRAERAD VLVTTPEKAD
SATRKHDSGR YSFITDVDCV VIDEVHLLDS EKRGAVLEVT VSRLRRLQDP RVVALSATMP
NIADVAEWLD APVQTTYEFG DAYRPVDLET GVKTYSHGSN AFADKYRRLY RALDLAEPHV
REDGQALVFV SSRQDTVQAA KKARDEITDR DIPIDSRGDY DFHNEAKELT NDTLRQSVTD
GVGFHHAGLG KEDRDRVEEW FKQGKIKLLF STSTLAWGVN LPARCVVIRD TKYHDPLEGE
TDISPLDVLQ MLGRAGRPGY DDVGYGWVVC DRADADKYRE LLKEGKEIES RLAAELESHL
NAEIAMGTIR GLEDVMEWLE TTFYYVRAES KPDEYEFATL RDRVRDTLES LVDDGFVAAD
DDLAIEPTAL GRLASKYYLR LDTARRFRRL ADRETLTVDS VLETVASAGE FDSVSARSAE
SDAIDRILDG RDTDLEDGHR KVFAILLAGM ADSIPSDLRS DAWVIRQNAL RLLAALAEFL
DRFAGPRAAN LACRVEARVE HGVSREAVAL TAVDGVGSGR AERLADAGLT SPTAVVDAGA
TELENAGMSG SVAERIVDAA RDCPRVDVDW GDFPDAIAVG ENELCEVAVT AVSGSARAGI
RVTVNDVEMT ATTTYLDGEA TVPVGVFGPP DAAELEFVVE VVFPDLPLMP VRATRTVRVE
//
