ID M0PKX6_9EURY Unreviewed; 780 AA.
AC M0PKX6;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=DEAD/DEAH box helicase {ECO:0000313|EMBL:EMA70274.1};
GN ORFNames=C462_11024 {ECO:0000313|EMBL:EMA70274.1};
OS Halorubrum arcis JCM 13916.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Halorubraceae; Halorubrum; Halorubrum distributum group.
OX NCBI_TaxID=1230455 {ECO:0000313|EMBL:EMA70274.1, ECO:0000313|Proteomes:UP000011528};
RN [1] {ECO:0000313|EMBL:EMA70274.1, ECO:0000313|Proteomes:UP000011528}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 13916 {ECO:0000313|EMBL:EMA70274.1,
RC ECO:0000313|Proteomes:UP000011528};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMA70274.1}.
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DR EMBL; AOJJ01000072; EMA70274.1; -; Genomic_DNA.
DR RefSeq; WP_007995914.1; NZ_AOJJ01000072.1.
DR AlphaFoldDB; M0PKX6; -.
DR STRING; 1230455.C462_11024; -.
DR PATRIC; fig|1230455.3.peg.2113; -.
DR Proteomes; UP000011528; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd18795; SF2_C_Ski2; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.10.3380.10; Sec63 N-terminal domain-like domain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004179; Sec63-dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR47961; DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED; 1.
DR PANTHER; PTHR47961:SF6; DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF14520; HHH_5; 1.
DR Pfam; PF02889; Sec63; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00973; Sec63; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF158702; Sec63 N-terminal domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:EMA70274.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 28..197
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 232..424
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 780 AA; 85889 MW; FF8CAE8F1CEBF90E CRC64;
MKVADAVPEF ADAFGFDEFN RMQREALPGI LETDHNVVAS APTASGKTAL AELAICKTLA
AGGTALFIAP LRALTNEKES EWERFEELGY SVYVVSGERD LNPRRAERAD VLVTTPEKAD
SATRKHDSAR YSFITDVDCV VIDEVHLLDS EKRGAVLEVT VSRLRRLQDP RVVALSATMP
NIDDVAEWLD APAETTYAFG DEYRPVDLET GVKTYSHGSN AFADKYRRLY RALDLAEPHV
REDGQALVFV SSRQDTVQAA KKARDEITER DIPIDSRDDY DFHNEAKELT NDTLRQSVTD
GVGFHHAGLG KDDRDRVEEW FKQGKIKFLF STSTLAWGVN LPARCVVIRD TKYHDPLEGE
TDISPLDVLQ MLGRAGRPEY DDVGYGWVVC DRADADKYRK LLRDGKEIES RLAADLESHL
NAEIAMGTIR GLEDVMAWLE TTFYYVRAQS EPEAYDFPTL RDRVRDTLES LVDDGFVAAD
DDLAIEPTGL GRLASKYYLR LDTARRFRRL ADRETLTVDS VLETVASAGE FDSVSARSAE
SDAIDRILDG RDTDLEDGHR KVFAILLAGM ADSIPSDLRS DAWVIRQNAL RLLAALAEFL
DRFAGPRAAN LARRVEARVE HGVSREAVAL TAIEGVGSGR AERLADAGLT SPADVVDAGT
KELENAGMSG SVAERIVEAA RDCPRIDVDW GDFPEAIAVG ENEMCEVAVT AVSGSARAGL
RVTVNDVEMT ATTTYLDGEA TVPVGVFGPP DADELEFVVE VVFPDLPLLP VTATRTVRVE
//
